The U.S. News & World Report ranks hospitals based on criteria, such as 30-day mortality, 30-day readmission, and how long patients tend to stay.

1MD Anderson Cancer CenterAurora Fierro / Getty ImagesIn 2024, the U.S. News & World Report chose the University of TexasMD Anderson Cancer Centerin Houston, Texas, as the number one cancer hospital in the United States. This hospital is one of the three original Comprehensive Cancer Centers in the United States. MD Anderson is widely considered to be one of the foremost cancer hospitals in the world.The MD Anderson Center provides care to over 179,000 people annually and employs nearly 25,000.It is also the top-ranked hospital in cancer funding from the National Institutes of Health.

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MD Anderson Cancer CenterAurora Fierro / Getty ImagesIn 2024, the U.S. News & World Report chose the University of TexasMD Anderson Cancer Centerin Houston, Texas, as the number one cancer hospital in the United States. This hospital is one of the three original Comprehensive Cancer Centers in the United States. MD Anderson is widely considered to be one of the foremost cancer hospitals in the world.The MD Anderson Center provides care to over 179,000 people annually and employs nearly 25,000.It is also the top-ranked hospital in cancer funding from the National Institutes of Health.

MD Anderson Cancer Center

Aurora Fierro / Getty Images

The University of Texas MD Anderson Center in Houston, Texas

In 2024, the U.S. News & World Report chose the University of TexasMD Anderson Cancer Centerin Houston, Texas, as the number one cancer hospital in the United States. This hospital is one of the three original Comprehensive Cancer Centers in the United States. MD Anderson is widely considered to be one of the foremost cancer hospitals in the world.

The MD Anderson Center provides care to over 179,000 people annually and employs nearly 25,000.It is also the top-ranked hospital in cancer funding from the National Institutes of Health.

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Memorial Sloan Kettering Cancer Center

The center treats hundreds of subtypes of cancers each year at its many locations in New York State and New Jersey. These include theEvelyn H. Lauder Breast Center, theSidney Kimmel Center for Prostate and Urologic Cancers, and theBendheim Integrative Medicine Center.

3Mayo ClinicThe Mayo Clinicin Rochester, Minnesota, is the original and largest Mayo Clinic campus. It is one of the most well-known hospitals in the world, with a tradition of cutting-edge care.The Mayo Clinic Cancer Center is based on three campuses—Rochester, Minnesota; Phoenix, Arizona; and Jacksonville, Florida. Mayo offers comprehensive oncological treatment to people from more than 140 countries.

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Mayo ClinicThe Mayo Clinicin Rochester, Minnesota, is the original and largest Mayo Clinic campus. It is one of the most well-known hospitals in the world, with a tradition of cutting-edge care.The Mayo Clinic Cancer Center is based on three campuses—Rochester, Minnesota; Phoenix, Arizona; and Jacksonville, Florida. Mayo offers comprehensive oncological treatment to people from more than 140 countries.

Mayo Clinic

The Mayo Clinicin Rochester, Minnesota, is the original and largest Mayo Clinic campus. It is one of the most well-known hospitals in the world, with a tradition of cutting-edge care.

The Mayo Clinic Cancer Center is based on three campuses—Rochester, Minnesota; Phoenix, Arizona; and Jacksonville, Florida. Mayo offers comprehensive oncological treatment to people from more than 140 countries.

4Dana-Farber Cancer InstituteBased in Boston, theDana-Farber Cancer Institutehas long been a leader in cancer research, education, and treatment. Dana-Farber’s sole focus since 1947 has been to provide innovative adult and pediatric cancer care and treatment.TheDana-Farber Brigham Cancer Centeris a collaboration between Dana-Farber Cancer Institute and Brigham and Women’s Hospital to provide state-of-the-art care for women and men with all types of cancer, includingbreast cancer. The center is staffed with leading surgeons, oncologists, and radiation oncologists. Some have pioneered techniques that have become the template for optimalbreast cancer treatment.

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Dana-Farber Cancer InstituteBased in Boston, theDana-Farber Cancer Institutehas long been a leader in cancer research, education, and treatment. Dana-Farber’s sole focus since 1947 has been to provide innovative adult and pediatric cancer care and treatment.TheDana-Farber Brigham Cancer Centeris a collaboration between Dana-Farber Cancer Institute and Brigham and Women’s Hospital to provide state-of-the-art care for women and men with all types of cancer, includingbreast cancer. The center is staffed with leading surgeons, oncologists, and radiation oncologists. Some have pioneered techniques that have become the template for optimalbreast cancer treatment.

Dana-Farber Cancer Institute

Based in Boston, theDana-Farber Cancer Institutehas long been a leader in cancer research, education, and treatment. Dana-Farber’s sole focus since 1947 has been to provide innovative adult and pediatric cancer care and treatment.

TheDana-Farber Brigham Cancer Centeris a collaboration between Dana-Farber Cancer Institute and Brigham and Women’s Hospital to provide state-of-the-art care for women and men with all types of cancer, includingbreast cancer. The center is staffed with leading surgeons, oncologists, and radiation oncologists. Some have pioneered techniques that have become the template for optimalbreast cancer treatment.

5City of Hope Comprehensive Cancer CenterCity of Hope Comprehensive Cancer Center’sDuarte, California, location outside Los Angeles has repeatedly made U.S. News & World Report’s Best Hospitals for Cancer rankings list.City of Hope Duarte is home to 1,000 scientists, 500 physicians, and 10,000 employees.It is especially noted for its high performance in four types of cancer treatment:LungProstateOvarianColonCity of Hope Comprehensive Cancer Center has locations in Southern California.

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City of Hope Comprehensive Cancer CenterCity of Hope Comprehensive Cancer Center’sDuarte, California, location outside Los Angeles has repeatedly made U.S. News & World Report’s Best Hospitals for Cancer rankings list.City of Hope Duarte is home to 1,000 scientists, 500 physicians, and 10,000 employees.It is especially noted for its high performance in four types of cancer treatment:LungProstateOvarianColonCity of Hope Comprehensive Cancer Center has locations in Southern California.

City of Hope Comprehensive Cancer Center

City of Hope Comprehensive Cancer Center’sDuarte, California, location outside Los Angeles has repeatedly made U.S. News & World Report’s Best Hospitals for Cancer rankings list.

City of Hope Duarte is home to 1,000 scientists, 500 physicians, and 10,000 employees.It is especially noted for its high performance in four types of cancer treatment:

City of Hope Comprehensive Cancer Center has locations in Southern California.

6Johns Hopkins HospitalThe Johns Hopkins Hospital in Baltimore, Maryland climbed to sixth place in the 2024-2025 U.S. News Best Hospitals for Cancer rankings.For more than 125 years, the Johns Hopkins Hospital has been at the forefront of disease diagnosis and treatment. As the teaching hospital affiliated with the Johns Hopkins University School of Medicine, it includes theJohns Hopkins Children’s Centerand theSydney Kimmel Comprehensive Cancer Center.

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Johns Hopkins HospitalThe Johns Hopkins Hospital in Baltimore, Maryland climbed to sixth place in the 2024-2025 U.S. News Best Hospitals for Cancer rankings.For more than 125 years, the Johns Hopkins Hospital has been at the forefront of disease diagnosis and treatment. As the teaching hospital affiliated with the Johns Hopkins University School of Medicine, it includes theJohns Hopkins Children’s Centerand theSydney Kimmel Comprehensive Cancer Center.

Johns Hopkins Hospital

The Johns Hopkins Hospital in Baltimore, Maryland climbed to sixth place in the 2024-2025 U.S. News Best Hospitals for Cancer rankings.

For more than 125 years, the Johns Hopkins Hospital has been at the forefront of disease diagnosis and treatment. As the teaching hospital affiliated with the Johns Hopkins University School of Medicine, it includes theJohns Hopkins Children’s Centerand theSydney Kimmel Comprehensive Cancer Center.

7UCSF Health-UCSF Medical CenterThe University of California, San Francisco (UCSF) Medical Center is a research and teaching hospital in San Francisco, California. It is the medical center of the University of California, San Francisco, and is affiliated with the UCSF School of Medicine.In 2015 UCSF opened a new 289-bed hospital serving women, children, and people with cancer in the Mission Bay neighborhood of San Francisco. UCSF hosts three hospitals:UCSF Benioff Children’s Hospital,UCSF Betty Irene Moore Women’s Hospital, andUCSF Bakar Cancer Hospital, and an outpatient facility.

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UCSF Health-UCSF Medical CenterThe University of California, San Francisco (UCSF) Medical Center is a research and teaching hospital in San Francisco, California. It is the medical center of the University of California, San Francisco, and is affiliated with the UCSF School of Medicine.In 2015 UCSF opened a new 289-bed hospital serving women, children, and people with cancer in the Mission Bay neighborhood of San Francisco. UCSF hosts three hospitals:UCSF Benioff Children’s Hospital,UCSF Betty Irene Moore Women’s Hospital, andUCSF Bakar Cancer Hospital, and an outpatient facility.

UCSF Health-UCSF Medical Center

The University of California, San Francisco (UCSF) Medical Center is a research and teaching hospital in San Francisco, California. It is the medical center of the University of California, San Francisco, and is affiliated with the UCSF School of Medicine.

In 2015 UCSF opened a new 289-bed hospital serving women, children, and people with cancer in the Mission Bay neighborhood of San Francisco. UCSF hosts three hospitals:UCSF Benioff Children’s Hospital,UCSF Betty Irene Moore Women’s Hospital, andUCSF Bakar Cancer Hospital, and an outpatient facility.

8Mount Sinai HospitalMount Sinai Hospital, which was founded in 1852, is a tertiary-care teaching facility based in New York. It offers comprehensive cancer care at multiple locations.The hospital hosts theMount Sinai Tisch Cancer Center, which comprises more than 250 cancer specialists, top-tier surgeons, and researchers. The cutting-edge cancer research performed atThe Tisch Cancer Instituteand various clinical trials allows patients to access the most advanced treatments.

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Mount Sinai HospitalMount Sinai Hospital, which was founded in 1852, is a tertiary-care teaching facility based in New York. It offers comprehensive cancer care at multiple locations.The hospital hosts theMount Sinai Tisch Cancer Center, which comprises more than 250 cancer specialists, top-tier surgeons, and researchers. The cutting-edge cancer research performed atThe Tisch Cancer Instituteand various clinical trials allows patients to access the most advanced treatments.

Mount Sinai Hospital

Mount Sinai Hospital, which was founded in 1852, is a tertiary-care teaching facility based in New York. It offers comprehensive cancer care at multiple locations.

The hospital hosts theMount Sinai Tisch Cancer Center, which comprises more than 250 cancer specialists, top-tier surgeons, and researchers. The cutting-edge cancer research performed atThe Tisch Cancer Instituteand various clinical trials allows patients to access the most advanced treatments.

9UCLA Medical CenterTheJonsson Comprehensive Cancer Centerat UCLA Health has been an NCI Comprehensive Cancer Center since 1976.With over 500 scientists and physicians doing research and providing care, and more than 400 active clinical trials for cancer care, this center is a leader in patient care. In 2024, U.S. News & World Report ranked UCLA Health first in quality care across multiple medical specialties in California and Los Angeles.

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UCLA Medical CenterTheJonsson Comprehensive Cancer Centerat UCLA Health has been an NCI Comprehensive Cancer Center since 1976.With over 500 scientists and physicians doing research and providing care, and more than 400 active clinical trials for cancer care, this center is a leader in patient care. In 2024, U.S. News & World Report ranked UCLA Health first in quality care across multiple medical specialties in California and Los Angeles.

UCLA Medical Center

TheJonsson Comprehensive Cancer Centerat UCLA Health has been an NCI Comprehensive Cancer Center since 1976.

With over 500 scientists and physicians doing research and providing care, and more than 400 active clinical trials for cancer care, this center is a leader in patient care. In 2024, U.S. News & World Report ranked UCLA Health first in quality care across multiple medical specialties in California and Los Angeles.

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Penn Medicine’sAbramson Cancer Centerhas been an NCI Comprehensive Cancer Center since 1973. It provides over 81,000 chemotherapy and 66,000 radiation treatments annually and runs nearly 600 active clinical trials.

Comprehensive Cancer Centers

If you or a loved one has been diagnosed with cancer, there are many reasons you may want to get care from a Comprehensive Cancer Center rather than a localoncologypractice or clinic.

It may be that your disease is an uncommon form of cancer, for instance, or one that isresistant to standard therapies. You may also be seeking asecond opinionfrom someone who is a leader in the field, especially for cancers that are rarer or harder to treat.

Whatever your motivation, these top-rated facilities are guaranteed to offer the highest level of care and expertise. Many engage in cutting-edge research and may be able to offer treatments that are either experimental or not yet available in other facilities.

Summary

Some of America’s top cancer hospitals include the University of Texas MD Anderson Cancer Center, the Memorial Sloan Kettering Cancer Center, and the Mayo Clinic.

12 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Olmstead MG, Lessem S, Powell R, et al.Methodology U.S. News & World Report 2023-24 Best Hospitals: Specialty Rankings.U.S. News & World Report; 2023.MD Anderson Cancer Center.Institutional Profile.Mayo Clinic.Mayo Clinic in Rochester, Minnesota.Dana-Farber Cancer Institute.Cancer Treatment: A Look at How It Has Evolved in 70 Years.City of Hope.Duarte Cancer Center.City of Hope.Locations - Duarte Cancer Center.Johns Hopkins Medicine.The Johns Hopkins Hospital.UCSF Health.Mission Bay.MountSinai.org.The Mount Sinai Hospital.UCLA Health.About UCLA Health.Penn Medicine.About the Abramson Cancer Center.National Cancer Institute.NCI-designated cancer centers.Additional ReadingAbudu RM, Cira MK, Pyle DHM, Duncan K.Landscape of global oncology research and training at National Cancer Institute-Designated Cancer Centers: results of the 2018 to 2019 Global Oncology Survey.J Glob Oncol. 2019;5:1–8. doi:10.1200/JGO.19.00308

12 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Olmstead MG, Lessem S, Powell R, et al.Methodology U.S. News & World Report 2023-24 Best Hospitals: Specialty Rankings.U.S. News & World Report; 2023.MD Anderson Cancer Center.Institutional Profile.Mayo Clinic.Mayo Clinic in Rochester, Minnesota.Dana-Farber Cancer Institute.Cancer Treatment: A Look at How It Has Evolved in 70 Years.City of Hope.Duarte Cancer Center.City of Hope.Locations - Duarte Cancer Center.Johns Hopkins Medicine.The Johns Hopkins Hospital.UCSF Health.Mission Bay.MountSinai.org.The Mount Sinai Hospital.UCLA Health.About UCLA Health.Penn Medicine.About the Abramson Cancer Center.National Cancer Institute.NCI-designated cancer centers.Additional ReadingAbudu RM, Cira MK, Pyle DHM, Duncan K.Landscape of global oncology research and training at National Cancer Institute-Designated Cancer Centers: results of the 2018 to 2019 Global Oncology Survey.J Glob Oncol. 2019;5:1–8. doi:10.1200/JGO.19.00308

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Olmstead MG, Lessem S, Powell R, et al.Methodology U.S. News & World Report 2023-24 Best Hospitals: Specialty Rankings.U.S. News & World Report; 2023.MD Anderson Cancer Center.Institutional Profile.Mayo Clinic.Mayo Clinic in Rochester, Minnesota.Dana-Farber Cancer Institute.Cancer Treatment: A Look at How It Has Evolved in 70 Years.City of Hope.Duarte Cancer Center.City of Hope.Locations - Duarte Cancer Center.Johns Hopkins Medicine.The Johns Hopkins Hospital.UCSF Health.Mission Bay.MountSinai.org.The Mount Sinai Hospital.UCLA Health.About UCLA Health.Penn Medicine.About the Abramson Cancer Center.National Cancer Institute.NCI-designated cancer centers.

Olmstead MG, Lessem S, Powell R, et al.Methodology U.S. News & World Report 2023-24 Best Hospitals: Specialty Rankings.U.S. News & World Report; 2023.

MD Anderson Cancer Center.Institutional Profile.

Mayo Clinic.Mayo Clinic in Rochester, Minnesota.

Dana-Farber Cancer Institute.Cancer Treatment: A Look at How It Has Evolved in 70 Years.

City of Hope.Duarte Cancer Center.

City of Hope.Locations - Duarte Cancer Center.

Johns Hopkins Medicine.The Johns Hopkins Hospital.

UCSF Health.Mission Bay.

MountSinai.org.The Mount Sinai Hospital.

UCLA Health.About UCLA Health.

Penn Medicine.About the Abramson Cancer Center.

National Cancer Institute.NCI-designated cancer centers.

Abudu RM, Cira MK, Pyle DHM, Duncan K.Landscape of global oncology research and training at National Cancer Institute-Designated Cancer Centers: results of the 2018 to 2019 Global Oncology Survey.J Glob Oncol. 2019;5:1–8. doi:10.1200/JGO.19.00308

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