Table of ContentsView AllTable of ContentsOverviewUsesSide EffectsPrecautionsDosageToxicityInteractionsSourcesAlternatives
Table of ContentsView All
View All
Table of Contents
Overview
Uses
Side Effects
Precautions
Dosage
Toxicity
Interactions
Sources
Alternatives
Resveratrol, a plant-based substance (polyphenol) found in foods and used in supplements, delivers numerous benefits, including lowering blood sugar, cholesterol, and blood pressure. It may also help slow cancer growth and improve memory.Resveratrol works as an antioxidant that fights inflammation.
Grapes, blueberries, apples, cranberries, and peanuts are some of the top natural sources of resveratrol. Supplements may contain active ingredients from food sources, but most use resveratrol extracted from the root of theJapanese knotweed plant.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
Verywell / Getty Images
What Is Resveratrol?
During the 1990s, researchers began to explore resveratrol extensively upon discovering that moderate red wine consumption appears to have numerous benefits for the heart. Initially, much of the research focused on resveratrol’s activities was related to the heart and inflammation.
It has become clear, however, that resveratrol has many more benefits to offer.
Resveratrol Supplement Benefits
Resveratrol has many potential health benefits due to its antioxidant and anti-inflammatory properties. These include the following:
What Are the Side Effects of Resveratrol?
Resveratrol is considered safe and well-tolerated when taken in recommended doses, but like any supplement, it may cause side effects in some people. Side effects are more common at high doses and may include:
While resveratrol is generally safe, especially when consumed in foods, not everyone should take resveratrol supplements. People with the following conditions should avoid resveratrol supplements:
Dosage: How Much Resveratrol Should I Take?
Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your needs.
The appropriate dosage of resveratrol varies, depending on the specific supplement product and intended use. Studies show that doses up to 5 grams (5,000 milligrams) daily are safe, but side effects are more common with doses above 2.5 grams daily.
Some research suggests that taking smaller doses is better than taking one large dose, as resveratrol is metabolized quickly.
Speak with a healthcare provider before you take resveratrol supplements. They can help you determine the best supplement and dosage based on your needs.
What Happens if I Take Too Much Resveratrol?
There is no established upper limit or recommended intake for resveratrol, and there have been no reports of toxicity or overdose in humans from dietary or supplemental sources. However, studies in rodents have shown that extremely high doses of resveratrol can lead to kidney and liver damage.
If you take very high doses of resveratrol, you may experience side effects or adverse events such as:
Seek medical attention if you suspect you have taken too much resveratrol.
Resveratrol can interact with certain medications, herbs, and supplements, potentially causing adverse effects and changing how these medicines work in your body. Resveratrol may interact with the following:
Supplements and herbs that have similar effects or potential interactions with resveratrol include:
To make an informed decision about resveratrol supplementation, carefully read the product’s ingredient list and nutrition facts panel, which provide information on the types and amounts of ingredients included.
It’s always best to review the supplement label with your healthcare provider so they can help you identify any potential interactions with foods, medications, or other supplements.
Sources of Resveratrol
Resveratrol is found in several dietary sources, including red wine, grapes, berries, and peanuts. The amounts of resveratrol in these sources vary, and research shows that it is not possible to absorb the recommended therapeutic doses of resveratrol through diet alone.Therefore, supplements may be a more reliable way to ensure you get the therapeutic benefits of resveratrol.
Food Sources of Resveratrol
Resveratrol is a natural compound found in various plant-based foods, particularly in the skins of red grapes and berries. Common food sources of resveratrol include:
12 Healthy Purple Foods to Enjoy
Resveratrol Supplements
Resveratrol is available in capsule, tablet, powder, liquid, and gummy forms. Capsules and tablets are the most commonly used and can be taken with water. Liquids may be a good option if you have difficulty swallowing pills or prefer to add resveratrol to your food or drinks.
There is no evidence to suggest that one form of resveratrol is superior to others in terms of efficacy. The supplement’s potency can vary, depending on the amount of resveratrol in the supplement and manufacturer. When shopping for resveratrol supplements, look for a high-quality product from a reputable brand.
Similar Supplements
Similar supplements to resveratrol include:
Like resveratrol, each of these supplements has antioxidant and anti-inflammatory properties that may benefit cardiovascular health, joint health, and cognitive function. Many of these compounds are being studied for their potential anti-cancer effects.
Taking these supplements alongside resveratrol is generally safe, but it is important to be mindful of possible interactions or side effects.
Summary
Resveratrol is a naturally occurring polyphenol compound in grape skins, berries, and peanuts. It is also available as a dietary supplement. Packed with antioxidant, anti-inflammatory, and anticancer compounds, resveratrol may benefit cardiovascular, joint, and metabolic health and improve cognitive function.
If you are considering using resveratrol to support your health, talk to a healthcare provider to determine if it is safe for you, especially if you have any health conditions or are taking medications. When shopping for resveratrol supplements, choose a reputable brand, and follow the recommended dosage guidelines.
32 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Koushki M, Amiri-Dashatan N, Ahmadi N, et al.Resveratrol: A miraculous natural compound for diseases treatment.Food Sci Nutr. 2018;6(8):2473-2490. doi:10.1002/fsn3.855Oregon State University.Resveratrol.Pezzuto J.Resveratrol: Twenty years of growth, development, and controversy.Biomol Ther (Seoul). 2019;27(1):1-14. doi:10.4062/biomolther.2018.176Buljeta I, Pichler A, Šimunović J, Kopjar M.Beneficial effects of red wine polyphenols on human health: comprehensive review.Curr Issues Mol Biol. 2023;45(2):782-798. doi:10.3390/cimb45020052Cheng CK, Luo JY, Lau CW, et al.Pharmacological basis and new insights of resveratrol action in the cardiovascular system.Br J Pharmacol. 2020;177(6):1258-1277. doi:10.1111/bph.14801Gu J, Li Z, Chen H, et al.Neuroprotective effect of trans-resveratrol in mild to moderate Alzheimer’s disease: A randomized, double-blind trial.Neurol Ther. 2021;10(2):905-917. doi:10.1007/s40120-021-00271-2Zhou Q, Wang Y, Han X, et al.Efficacy of resveratrol supplementation on glucose and lipid metabolism: a meta-analysis and systematic review.Front Physiol. 2022;13.Hou CY, Tain YL, Yu HR, Huang LT.The effects of resveratrol in the treatment of metabolic syndrome.Int J Mol Sci. 2019;20(3):535. doi:10.3390/ijms20030535Mahjabeen W, Khan DA, Mirza SA.Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.Complement Ther Med. 2022;66:102819. doi:10.1016/j.ctim.2022.102819Fadlalmola H, Elhusein A, Al-Sayaghi K, et al.Efficacy of resveratrol in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized clinical trials.Pan Afr Med J. 2023 Mar;44(1):134. doi:10.11604/pamj.2023.44.134.32404Marouf BH, Hussain SA, Ali ZS, Ahmmad RS.Resveratrol supplementation reduces pain and inflammation in knee osteoarthritis patients treated with Meloxicam: A randomized placebo-controlled study.J Med Food. 2018;10.1089/jmf.2017.4176. doi:10.1089/jmf.2017.4176Sheng S, Wang X, Liu X, et al.The role of resveratrol on rheumatoid arthritis: From bench to bedside.Front Pharmacol. 2022;13. doi:10.3389/fphar.2022.829677Arabzadeh A, Mortezazadeh T, Aryafar T, Gharepapagh E, Majdaeen M, Farhood B.Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review.Cancer Cell International. 2021;21(1):391. doi:10.1186/s12935-021-02099-0Vajdi M, Azar P, Mahmoodpoor A, et al.A comprehensive insight into the molecular and cellular mechanisms of action of resveratrol on complications of sepsis: A systematic review.Phytother Res. 2023 Sep;37(9):3780-3808. doi:10.1002/ptr.7917Abdollahi S, Vajdi M, Meshkini F, et al.Resveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.Nutr Res. 2023 May;113(1):1-13. doi:10.1016/j.nutres.2023.03.002Zhou DD, Luo M, Huang SY, et al.Effects and mechanisms of resveratrol on aging and age-related diseases.Oxid Med Cell Longev. 2021;2021:9932218. doi:10.1155/2021/9932218Lv C, Zhang Y, Shen L.Preliminary clinical effect evaluation of resveratrol in adults with allergic rhinitis.IAA. 2018;175(4):231-236. doi: 10.1159/000486959Ratz-Łyko A, Arct J.Resveratrol as an active ingredient for cosmetic and dermatological applications: a review.J Cosmet Laser Ther. 2019;21(2):84-90. doi:10.1080/14764172.2018.1469767Abu-Amero KK, Kondkar AA, Chalam KV.Resveratrol and ophthalmic diseases.Nutrients. 2016;8(4):200. doi:10.3390/nu8040200Alesci A, Nicosia N, Fumia A, Giorgianni F, Santini A, Cicero N.Resveratrol and immune cells: A link to improve human health.Molecules. 2022 Jan;27(2):424. doi:10.3390/molecules27020424Salehi B, Mishra AP, Nigam M, et al.Resveratrol: a double-edged sword in health benefits.Biomedicines. 2018;6(3):91. doi:10.3390/biomedicines6030091Susan G. Komen Foundation.Resveratrol.Ramírez-Garza SL, Laveriano-Santos EP, Marhuenda-Muñoz M, et al.Health effects of resveratrol: results from human intervention trials.Nutrients. 2018;10(12):1892. doi:10.3390/nu10121892Shaito A, Posadino AM, Younes N, et al.Potential adverse effects of resveratrol: A literature review.Int J Mol Sci. 2020;21(6):2084. doi:10.3390/ijms21062084Weiskirchen S, Weiskirchen R.Resveratrol: How much wine do you have to drink to stay healthy?Adv Nutr. 2016;7(4):706-718. doi:10.3945/an.115.011627National Institute on Alcohol Abuse and Alcoholism.What is a standard drink?World Health Organization.No level of alcohol consumption is safe for our health.Barbería-Latasa M, Gea A, Martínez-González M.Alcohol, drinking pattern, and chronic disease.Nutrients. 2022 May;14(9):1954. doi:10.3390/nu14091954Inchingolo AD, Inchingolo AM, Malcangi G, et al.Effects of resveratrol, curcumin and quercetin supplementation on bone metabolism-a systematic review.Nutrients. 2022;14(17):3519. doi:10.3390/nu14173519Chan EWC, Wong CW, Tan YH, Foo JPY, Wong SK, Chan HT.Resveratrol and pterostilbene: A comparative overview of their chemistry, biosynthesis, plant sources and pharmacological properties.J App Pharm Sci. 2019;9,(7):124-129. doi: 10.7324/JAPS.2019.90717Amin ARMR, Wang D, Nannapaneni S, Lamichhane R, Chen ZG, Shin DM.Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growthin vivoin head and neck cancer models.Oncol Rep. 2021;45(5):87. doi:10.3892/or.2021.8038McCubrey JA, Lertpiriyapong K, Steelman LS, et al.Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.Aging (Albany NY). 2017;9(6):1477-1536. doi:10.18632/aging.101250
32 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Koushki M, Amiri-Dashatan N, Ahmadi N, et al.Resveratrol: A miraculous natural compound for diseases treatment.Food Sci Nutr. 2018;6(8):2473-2490. doi:10.1002/fsn3.855Oregon State University.Resveratrol.Pezzuto J.Resveratrol: Twenty years of growth, development, and controversy.Biomol Ther (Seoul). 2019;27(1):1-14. doi:10.4062/biomolther.2018.176Buljeta I, Pichler A, Šimunović J, Kopjar M.Beneficial effects of red wine polyphenols on human health: comprehensive review.Curr Issues Mol Biol. 2023;45(2):782-798. doi:10.3390/cimb45020052Cheng CK, Luo JY, Lau CW, et al.Pharmacological basis and new insights of resveratrol action in the cardiovascular system.Br J Pharmacol. 2020;177(6):1258-1277. doi:10.1111/bph.14801Gu J, Li Z, Chen H, et al.Neuroprotective effect of trans-resveratrol in mild to moderate Alzheimer’s disease: A randomized, double-blind trial.Neurol Ther. 2021;10(2):905-917. doi:10.1007/s40120-021-00271-2Zhou Q, Wang Y, Han X, et al.Efficacy of resveratrol supplementation on glucose and lipid metabolism: a meta-analysis and systematic review.Front Physiol. 2022;13.Hou CY, Tain YL, Yu HR, Huang LT.The effects of resveratrol in the treatment of metabolic syndrome.Int J Mol Sci. 2019;20(3):535. doi:10.3390/ijms20030535Mahjabeen W, Khan DA, Mirza SA.Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.Complement Ther Med. 2022;66:102819. doi:10.1016/j.ctim.2022.102819Fadlalmola H, Elhusein A, Al-Sayaghi K, et al.Efficacy of resveratrol in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized clinical trials.Pan Afr Med J. 2023 Mar;44(1):134. doi:10.11604/pamj.2023.44.134.32404Marouf BH, Hussain SA, Ali ZS, Ahmmad RS.Resveratrol supplementation reduces pain and inflammation in knee osteoarthritis patients treated with Meloxicam: A randomized placebo-controlled study.J Med Food. 2018;10.1089/jmf.2017.4176. doi:10.1089/jmf.2017.4176Sheng S, Wang X, Liu X, et al.The role of resveratrol on rheumatoid arthritis: From bench to bedside.Front Pharmacol. 2022;13. doi:10.3389/fphar.2022.829677Arabzadeh A, Mortezazadeh T, Aryafar T, Gharepapagh E, Majdaeen M, Farhood B.Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review.Cancer Cell International. 2021;21(1):391. doi:10.1186/s12935-021-02099-0Vajdi M, Azar P, Mahmoodpoor A, et al.A comprehensive insight into the molecular and cellular mechanisms of action of resveratrol on complications of sepsis: A systematic review.Phytother Res. 2023 Sep;37(9):3780-3808. doi:10.1002/ptr.7917Abdollahi S, Vajdi M, Meshkini F, et al.Resveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.Nutr Res. 2023 May;113(1):1-13. doi:10.1016/j.nutres.2023.03.002Zhou DD, Luo M, Huang SY, et al.Effects and mechanisms of resveratrol on aging and age-related diseases.Oxid Med Cell Longev. 2021;2021:9932218. doi:10.1155/2021/9932218Lv C, Zhang Y, Shen L.Preliminary clinical effect evaluation of resveratrol in adults with allergic rhinitis.IAA. 2018;175(4):231-236. doi: 10.1159/000486959Ratz-Łyko A, Arct J.Resveratrol as an active ingredient for cosmetic and dermatological applications: a review.J Cosmet Laser Ther. 2019;21(2):84-90. doi:10.1080/14764172.2018.1469767Abu-Amero KK, Kondkar AA, Chalam KV.Resveratrol and ophthalmic diseases.Nutrients. 2016;8(4):200. doi:10.3390/nu8040200Alesci A, Nicosia N, Fumia A, Giorgianni F, Santini A, Cicero N.Resveratrol and immune cells: A link to improve human health.Molecules. 2022 Jan;27(2):424. doi:10.3390/molecules27020424Salehi B, Mishra AP, Nigam M, et al.Resveratrol: a double-edged sword in health benefits.Biomedicines. 2018;6(3):91. doi:10.3390/biomedicines6030091Susan G. Komen Foundation.Resveratrol.Ramírez-Garza SL, Laveriano-Santos EP, Marhuenda-Muñoz M, et al.Health effects of resveratrol: results from human intervention trials.Nutrients. 2018;10(12):1892. doi:10.3390/nu10121892Shaito A, Posadino AM, Younes N, et al.Potential adverse effects of resveratrol: A literature review.Int J Mol Sci. 2020;21(6):2084. doi:10.3390/ijms21062084Weiskirchen S, Weiskirchen R.Resveratrol: How much wine do you have to drink to stay healthy?Adv Nutr. 2016;7(4):706-718. doi:10.3945/an.115.011627National Institute on Alcohol Abuse and Alcoholism.What is a standard drink?World Health Organization.No level of alcohol consumption is safe for our health.Barbería-Latasa M, Gea A, Martínez-González M.Alcohol, drinking pattern, and chronic disease.Nutrients. 2022 May;14(9):1954. doi:10.3390/nu14091954Inchingolo AD, Inchingolo AM, Malcangi G, et al.Effects of resveratrol, curcumin and quercetin supplementation on bone metabolism-a systematic review.Nutrients. 2022;14(17):3519. doi:10.3390/nu14173519Chan EWC, Wong CW, Tan YH, Foo JPY, Wong SK, Chan HT.Resveratrol and pterostilbene: A comparative overview of their chemistry, biosynthesis, plant sources and pharmacological properties.J App Pharm Sci. 2019;9,(7):124-129. doi: 10.7324/JAPS.2019.90717Amin ARMR, Wang D, Nannapaneni S, Lamichhane R, Chen ZG, Shin DM.Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growthin vivoin head and neck cancer models.Oncol Rep. 2021;45(5):87. doi:10.3892/or.2021.8038McCubrey JA, Lertpiriyapong K, Steelman LS, et al.Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.Aging (Albany NY). 2017;9(6):1477-1536. doi:10.18632/aging.101250
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Koushki M, Amiri-Dashatan N, Ahmadi N, et al.Resveratrol: A miraculous natural compound for diseases treatment.Food Sci Nutr. 2018;6(8):2473-2490. doi:10.1002/fsn3.855Oregon State University.Resveratrol.Pezzuto J.Resveratrol: Twenty years of growth, development, and controversy.Biomol Ther (Seoul). 2019;27(1):1-14. doi:10.4062/biomolther.2018.176Buljeta I, Pichler A, Šimunović J, Kopjar M.Beneficial effects of red wine polyphenols on human health: comprehensive review.Curr Issues Mol Biol. 2023;45(2):782-798. doi:10.3390/cimb45020052Cheng CK, Luo JY, Lau CW, et al.Pharmacological basis and new insights of resveratrol action in the cardiovascular system.Br J Pharmacol. 2020;177(6):1258-1277. doi:10.1111/bph.14801Gu J, Li Z, Chen H, et al.Neuroprotective effect of trans-resveratrol in mild to moderate Alzheimer’s disease: A randomized, double-blind trial.Neurol Ther. 2021;10(2):905-917. doi:10.1007/s40120-021-00271-2Zhou Q, Wang Y, Han X, et al.Efficacy of resveratrol supplementation on glucose and lipid metabolism: a meta-analysis and systematic review.Front Physiol. 2022;13.Hou CY, Tain YL, Yu HR, Huang LT.The effects of resveratrol in the treatment of metabolic syndrome.Int J Mol Sci. 2019;20(3):535. doi:10.3390/ijms20030535Mahjabeen W, Khan DA, Mirza SA.Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.Complement Ther Med. 2022;66:102819. doi:10.1016/j.ctim.2022.102819Fadlalmola H, Elhusein A, Al-Sayaghi K, et al.Efficacy of resveratrol in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized clinical trials.Pan Afr Med J. 2023 Mar;44(1):134. doi:10.11604/pamj.2023.44.134.32404Marouf BH, Hussain SA, Ali ZS, Ahmmad RS.Resveratrol supplementation reduces pain and inflammation in knee osteoarthritis patients treated with Meloxicam: A randomized placebo-controlled study.J Med Food. 2018;10.1089/jmf.2017.4176. doi:10.1089/jmf.2017.4176Sheng S, Wang X, Liu X, et al.The role of resveratrol on rheumatoid arthritis: From bench to bedside.Front Pharmacol. 2022;13. doi:10.3389/fphar.2022.829677Arabzadeh A, Mortezazadeh T, Aryafar T, Gharepapagh E, Majdaeen M, Farhood B.Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review.Cancer Cell International. 2021;21(1):391. doi:10.1186/s12935-021-02099-0Vajdi M, Azar P, Mahmoodpoor A, et al.A comprehensive insight into the molecular and cellular mechanisms of action of resveratrol on complications of sepsis: A systematic review.Phytother Res. 2023 Sep;37(9):3780-3808. doi:10.1002/ptr.7917Abdollahi S, Vajdi M, Meshkini F, et al.Resveratrol may mildly improve renal function in the general adult population: A systematic review and meta-analysis of randomized controlled clinical trials.Nutr Res. 2023 May;113(1):1-13. doi:10.1016/j.nutres.2023.03.002Zhou DD, Luo M, Huang SY, et al.Effects and mechanisms of resveratrol on aging and age-related diseases.Oxid Med Cell Longev. 2021;2021:9932218. doi:10.1155/2021/9932218Lv C, Zhang Y, Shen L.Preliminary clinical effect evaluation of resveratrol in adults with allergic rhinitis.IAA. 2018;175(4):231-236. doi: 10.1159/000486959Ratz-Łyko A, Arct J.Resveratrol as an active ingredient for cosmetic and dermatological applications: a review.J Cosmet Laser Ther. 2019;21(2):84-90. doi:10.1080/14764172.2018.1469767Abu-Amero KK, Kondkar AA, Chalam KV.Resveratrol and ophthalmic diseases.Nutrients. 2016;8(4):200. doi:10.3390/nu8040200Alesci A, Nicosia N, Fumia A, Giorgianni F, Santini A, Cicero N.Resveratrol and immune cells: A link to improve human health.Molecules. 2022 Jan;27(2):424. doi:10.3390/molecules27020424Salehi B, Mishra AP, Nigam M, et al.Resveratrol: a double-edged sword in health benefits.Biomedicines. 2018;6(3):91. doi:10.3390/biomedicines6030091Susan G. Komen Foundation.Resveratrol.Ramírez-Garza SL, Laveriano-Santos EP, Marhuenda-Muñoz M, et al.Health effects of resveratrol: results from human intervention trials.Nutrients. 2018;10(12):1892. doi:10.3390/nu10121892Shaito A, Posadino AM, Younes N, et al.Potential adverse effects of resveratrol: A literature review.Int J Mol Sci. 2020;21(6):2084. doi:10.3390/ijms21062084Weiskirchen S, Weiskirchen R.Resveratrol: How much wine do you have to drink to stay healthy?Adv Nutr. 2016;7(4):706-718. doi:10.3945/an.115.011627National Institute on Alcohol Abuse and Alcoholism.What is a standard drink?World Health Organization.No level of alcohol consumption is safe for our health.Barbería-Latasa M, Gea A, Martínez-González M.Alcohol, drinking pattern, and chronic disease.Nutrients. 2022 May;14(9):1954. doi:10.3390/nu14091954Inchingolo AD, Inchingolo AM, Malcangi G, et al.Effects of resveratrol, curcumin and quercetin supplementation on bone metabolism-a systematic review.Nutrients. 2022;14(17):3519. doi:10.3390/nu14173519Chan EWC, Wong CW, Tan YH, Foo JPY, Wong SK, Chan HT.Resveratrol and pterostilbene: A comparative overview of their chemistry, biosynthesis, plant sources and pharmacological properties.J App Pharm Sci. 2019;9,(7):124-129. doi: 10.7324/JAPS.2019.90717Amin ARMR, Wang D, Nannapaneni S, Lamichhane R, Chen ZG, Shin DM.Combination of resveratrol and green tea epigallocatechin gallate induces synergistic apoptosis and inhibits tumor growthin vivoin head and neck cancer models.Oncol Rep. 2021;45(5):87. doi:10.3892/or.2021.8038McCubrey JA, Lertpiriyapong K, Steelman LS, et al.Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs.Aging (Albany NY). 2017;9(6):1477-1536. doi:10.18632/aging.101250
Koushki M, Amiri-Dashatan N, Ahmadi N, et al.Resveratrol: A miraculous natural compound for diseases treatment.Food Sci Nutr. 2018;6(8):2473-2490. doi:10.1002/fsn3.855
Oregon State University.Resveratrol.
Pezzuto J.Resveratrol: Twenty years of growth, development, and controversy.Biomol Ther (Seoul). 2019;27(1):1-14. doi:10.4062/biomolther.2018.176
Buljeta I, Pichler A, Šimunović J, Kopjar M.Beneficial effects of red wine polyphenols on human health: comprehensive review.Curr Issues Mol Biol. 2023;45(2):782-798. doi:10.3390/cimb45020052
Cheng CK, Luo JY, Lau CW, et al.Pharmacological basis and new insights of resveratrol action in the cardiovascular system.Br J Pharmacol. 2020;177(6):1258-1277. doi:10.1111/bph.14801
Gu J, Li Z, Chen H, et al.Neuroprotective effect of trans-resveratrol in mild to moderate Alzheimer’s disease: A randomized, double-blind trial.Neurol Ther. 2021;10(2):905-917. doi:10.1007/s40120-021-00271-2
Zhou Q, Wang Y, Han X, et al.Efficacy of resveratrol supplementation on glucose and lipid metabolism: a meta-analysis and systematic review.Front Physiol. 2022;13.
Hou CY, Tain YL, Yu HR, Huang LT.The effects of resveratrol in the treatment of metabolic syndrome.Int J Mol Sci. 2019;20(3):535. doi:10.3390/ijms20030535
Mahjabeen W, Khan DA, Mirza SA.Role of resveratrol supplementation in regulation of glucose hemostasis, inflammation and oxidative stress in patients with diabetes mellitus type 2: A randomized, placebo-controlled trial.Complement Ther Med. 2022;66:102819. doi:10.1016/j.ctim.2022.102819
Fadlalmola H, Elhusein A, Al-Sayaghi K, et al.Efficacy of resveratrol in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized clinical trials.Pan Afr Med J. 2023 Mar;44(1):134. doi:10.11604/pamj.2023.44.134.32404
Marouf BH, Hussain SA, Ali ZS, Ahmmad RS.Resveratrol supplementation reduces pain and inflammation in knee osteoarthritis patients treated with Meloxicam: A randomized placebo-controlled study.J Med Food. 2018;10.1089/jmf.2017.4176. doi:10.1089/jmf.2017.4176
Sheng S, Wang X, Liu X, et al.The role of resveratrol on rheumatoid arthritis: From bench to bedside.Front Pharmacol. 2022;13. doi:10.3389/fphar.2022.829677
Arabzadeh A, Mortezazadeh T, Aryafar T, Gharepapagh E, Majdaeen M, Farhood B.Therapeutic potentials of resveratrol in combination with radiotherapy and chemotherapy during glioblastoma treatment: a mechanistic review.Cancer Cell International. 2021;21(1):391. doi:10.1186/s12935-021-02099-0
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