Table of ContentsView AllTable of ContentsCommon Risk FactorsGeneticsLifestyle Risk Factors
Table of ContentsView All
View All
Table of Contents
Common Risk Factors
Genetics
Lifestyle Risk Factors
There is no known cause ofliposarcoma. Researchers have discovered certain risk factors that may increase a person’s chances of developing this type of cancer, including genetics and previous exposure to radiation or toxic chemicals.
This article will review the risk factors associated with liposarcoma and what you can do to reduce your risk.

A risk factor is anything that increases the likelihood of developing a disease. There are no known causes of liposarcoma, but some risk factors have been identified for liposarcoma, including:
There are some inherited genetic conditions that are known to increase a person’s predisposition for developing cancer. Some of these conditions can increase the risk of liposarcoma, including:
If you or anyone in your family has one of these conditions, it may be worth having a conversation with your healthcare provider. They can give you information aboutgenetic testing, what you can do to reduce your cancer risk, and how to set up routine screenings to aid in catching any cancer that may develop as early as possible.
Lifestyle factors, including diet, exercise, and smoking, have not been associated with an increased risk of developing liposarcoma.However, adopting healthy habits such as limiting alcohol, avoiding tobacco products, staying physically fit, and eating well are measures that have shown promise in reducing a person’s overall cancer risk.
Will Cancer Ever Be Cured?
Summary
There is no definitive cause of liposarcoma. Certain risk factors, including being male, having prior exposure to radiation (such as during treatment for an earlier cancer), occupational exposure to industrial chemicals (particularly vinyl chloride), and having a familial cancer syndrome, may raise your likelihood of developing liposarcoma.
A Word From Verywell
If you have beendiagnosed with liposarcoma, you may be wondering how this happened to you. Know that there is nothing you could have done to avoid this very rare cancer. It was beyond your control, but you are not alone, and you can get through this with a strong support system around you.
If you know that you have a predisposition to cancer due to a genetic condition, make sure to have a conversation with your healthcare provider regarding your options and how you can lower your risk. Your healthcare provider can help you create a plan and a screening protocol that is right for you.
5 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Cleveland Clinic.Liposarcoma.Bock S, Hoffmann DG, Jiang Y, Chen H, Il’yasova D.Increasing incidence of liposarcoma: a population-based study of national surveillance databases, 2001-2016.Int J Environ Res Public Health. 2020;17(8):2710. doi:10.3390/ijerph17082710American Cancer Society.Risk factors for soft tissue sarcomas.National Cancer Institute.Adult soft tissue sarcoma treatment (PDQ)—health professional version.Lewandowska AM, Rudzki M, Rudzki S, Lewandowski T, Laskowska B.Environmental risk factors for cancer - review paper.Ann Agric Environ Med. 2019;26(1):1-7. doi:10.26444/aaem/94299
5 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Cleveland Clinic.Liposarcoma.Bock S, Hoffmann DG, Jiang Y, Chen H, Il’yasova D.Increasing incidence of liposarcoma: a population-based study of national surveillance databases, 2001-2016.Int J Environ Res Public Health. 2020;17(8):2710. doi:10.3390/ijerph17082710American Cancer Society.Risk factors for soft tissue sarcomas.National Cancer Institute.Adult soft tissue sarcoma treatment (PDQ)—health professional version.Lewandowska AM, Rudzki M, Rudzki S, Lewandowski T, Laskowska B.Environmental risk factors for cancer - review paper.Ann Agric Environ Med. 2019;26(1):1-7. doi:10.26444/aaem/94299
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Cleveland Clinic.Liposarcoma.Bock S, Hoffmann DG, Jiang Y, Chen H, Il’yasova D.Increasing incidence of liposarcoma: a population-based study of national surveillance databases, 2001-2016.Int J Environ Res Public Health. 2020;17(8):2710. doi:10.3390/ijerph17082710American Cancer Society.Risk factors for soft tissue sarcomas.National Cancer Institute.Adult soft tissue sarcoma treatment (PDQ)—health professional version.Lewandowska AM, Rudzki M, Rudzki S, Lewandowski T, Laskowska B.Environmental risk factors for cancer - review paper.Ann Agric Environ Med. 2019;26(1):1-7. doi:10.26444/aaem/94299
Cleveland Clinic.Liposarcoma.
Bock S, Hoffmann DG, Jiang Y, Chen H, Il’yasova D.Increasing incidence of liposarcoma: a population-based study of national surveillance databases, 2001-2016.Int J Environ Res Public Health. 2020;17(8):2710. doi:10.3390/ijerph17082710
American Cancer Society.Risk factors for soft tissue sarcomas.
National Cancer Institute.Adult soft tissue sarcoma treatment (PDQ)—health professional version.
Lewandowska AM, Rudzki M, Rudzki S, Lewandowski T, Laskowska B.Environmental risk factors for cancer - review paper.Ann Agric Environ Med. 2019;26(1):1-7. doi:10.26444/aaem/94299
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