Key TakeawaysRegeneron is the name of the company that has developed an antibody cocktail that is aimed at treating COVID-19.The antibody cocktail is not yet available to the general public.Though previously reported, Regeneron does not include stem cells.While there have been promising results, it is still too soon to know whether or not Regeneron will be approved to treat COVID-19.
Key Takeaways
Regeneron is the name of the company that has developed an antibody cocktail that is aimed at treating COVID-19.The antibody cocktail is not yet available to the general public.Though previously reported, Regeneron does not include stem cells.While there have been promising results, it is still too soon to know whether or not Regeneron will be approved to treat COVID-19.
While some reports have stated Regeneron’s antibody cocktail contains embryonic stem cells and human fetal tissue, directly conflicting with the President’s pro-life platform, Soma Mandal, MD, a board-certified internist at Summit Medical Group in Berkeley Heights, New Jersey, says that’s not the case.
“The drug’s potency was tested in a lab using HEK 293T cells,” Mandal tells Verywell. “This is a cell line which was originally derived from the kidney tissue of a fetus aborted in the Netherlands in the 1970s. The cells were used in the testing of the antibody; however, there is no fetal tissue in the final product.”
Mandal explains that because they are so adaptable, stem cells are often used to test new drugs for safety and effectiveness.
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According to astatementfrom George D. Yancopoulos, MD, PhD, President and Chief Scientific Officer of Regeneron, early data from 275 non-hospitalized COVID-19 patients shows that REGN-COV2 “rapidly reduced viral load and associated symptoms.”
Yancopoulos says the drug appears most helpful for patients unable to clear the virus on their own.
“The greatest treatment benefit was in patients who had not mounted their own effective immune response, suggesting that REGN-COV2 could provide a therapeutic substitute for the naturally-occurring immune response,” he says.
What the Regeneron Antibody Cocktail IsNot
In a White House video on October 7, President Trump said that while “they call [REGN-COV2] therapeutic, to me it wasn’t therapeutic, it just made me better…I call that a cure.”
Experts warn against using such language, noting that while treatments and vaccines are being developed, COVID-19 has no cure.
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“[It’s] still too early to determine the success of the Regeneron antibody cocktail, despite the fact that President Trump received it,” Mandal says. “The real evidence of the drug’s effectiveness will come from larger randomized clinical trials which are ongoing.”
Johannes agrees, adding that monoclonal antibodies have been successful at treating conditions like autoimmune diseases, various cancers, and asthma.
“Despite our optimism for the efficacy and safety of monoclonal antibodies to treat COVID-19, it is imperative that we prove that this approach is truly effective and safe with these randomized controlled trials,” he says.
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What’s Next For Regeneron?
“If a EUA is granted, the government has committed to making these doses available to the American people at no cost,” she says. “At this time, there are doses available for approximately 50,000 patients; doses for 300,000 patients are expected to be available within the next few months.”
The information in this article is current as of the date listed, which means newer information may be available when you read this. For the most recent updates on COVID-19, visit ourcoronavirus news page.
1 SourceVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Regeneron.Regeneron’s REGN-COV2 Antibody Cocktail Reduced Viral Levels and Improved Symptoms in Non-hospitalized COVID-19 Patients. September 29, 2020.
1 Source
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Regeneron.Regeneron’s REGN-COV2 Antibody Cocktail Reduced Viral Levels and Improved Symptoms in Non-hospitalized COVID-19 Patients. September 29, 2020.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Regeneron.Regeneron’s REGN-COV2 Antibody Cocktail Reduced Viral Levels and Improved Symptoms in Non-hospitalized COVID-19 Patients. September 29, 2020.
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