Table of ContentsView AllTable of ContentsWhat Is Dysbiosis?TypesHealth ProblemsCausesSymptomsDiagnosisImproving Gut Health

Table of ContentsView All

View All

Table of Contents

What Is Dysbiosis?

Types

Health Problems

Causes

Symptoms

Diagnosis

Improving Gut Health

Gutdysbiosisis a state in which there is an imbalance of microorganisms within our gastrointestinal tract. When in balance, these colonies of microorganisms tend to have a favorable effect on our bodies. When there is an imbalance, we may experience unwanted symptoms.

In this article, learn about what gut dysbiosis is, its causes, and the symptoms it can cause. It also covers how to diagnose it and ways to improve gut health.

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gut bacteria

Gut dysbiosis means there is an imbalance of microorganisms in the intestines. Dysbiosis is also known as intestinal or gastrointestinal dysbiosis.

Gut microorganisms, collectively known asgut flora, consist predominantly of various strains of bacteria and, to a lesser extent, include fungi andprotozoa. The gut flora are essential for digestion and immune functioning.A state of dysbiosis, therefore, will result in digestive and other systemic symptoms.

Types of Dysbiosis

There is more than one type of gut dysbiosis. Some people have too much harmful bacteria in their digestive system, while others don’t have enough good bacteria. Gut dysbiosis may also describe an imbalance in the microbe community in your gut or a lack of microbe diversity. There are three main types of gut dysbiosis:

More than one of these types of dysbiosis can co-occur.

Health Problems Stemming From Gut Dysbiosis

Dysbiosis has been identified as playing a possible role in a variety of health problems. What this role might be is not always clear. It is theorized that the balance of gut bacteria can affect the immune system and the health of the lining of the gut (increased intestinal permeability). Health conditions in which dysbiosis might play a part are not exclusively related to digestion and can include:

Gut dysbiosis and weight gain may be related as well. Some studies, for example, have found a link between obesity and certain gut microorganisms.

Causes of Dysbiosis

Some factors that appear to contribute to a state of dysbiosis include:

Symptoms of Dysbiosis

The symptoms of gut dysbiosis may include:

Diagnosing Dysbiosis

Because there are a lot of individual differences between the gut microbiotas of healthy people, there’s no standard way to arrive at a dysbiosis diagnosis. Some healthcare providers may order the following tests:

Because certain conditions like IBS and long-term use of antibiotics are associated with dysbiosis, your healthcare provider will also ask you about your medical history.

In theory, dysbiosis can be cured through improved dietary and lifestyle habits. Adopting a dysbiosis diet might mean eating high-quality proteins from sources like lean meat and fish, increasing your fiber intake, and avoiding sugar, saturated fat, and refined flour.

Lifestyle changes might include engaging inmind/body techniquesfor stress management.Some alternative health practitioners recommend the use ofbone broth, but there is no clinical research to back up this recommendation.

The research on the relationship between gut dysbiosis and our health is still in preliminary stages, although it is rapidly expanding. As of now, there are a few dysbiosis treatment options that have received some research support for improving a state of dysbiosis:

For people with irritable bowel syndrome, a specific antibiotic, Xifaxan (rifaximin), targets dysbiosis in the intestines.

This area of medicine is still in its preliminary stages. Clear information about improving dysbiosis and its effect on health disorders is not yet available. However, this area of inquiry appears to be a promising one.

5 Ways to Reduce Inflammation and Improve Gut Health

Summary

Gut dysbiosis occurs when the balance of bacteria in the gut becomes imbalanced because there is not the ideal number of good or bad bacteria or a combination of the two. It can happen for a variety of reasons, including due to diet, stress, antibiotic use, or as a result of illnesses. Gut dysbiosis presents differently depending on the type and the individual but can include gas, bloating, nausea, bad breath, abdominal pain, diarrhea, and/or constipation.

Gut health can improve with attention to managing stress, diet, and interventions like prebiotics and probiotics in your diet and as supplements. More research is needed to understand how to address gut dysbiosis best.

15 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Belizário JE, Faintuch J, Garay-Malpartida M.Gut microbiome dysbiosis and immunometabolism: New frontiers for treatment of metabolic diseases.Mediators Inflamm. 2018;2018:2037838. doi:10.1155/2018/2037838

DeGruttola AK, Low D, Mizoguchi A, Mizoguchi E.Current understanding of dysbiosis in disease in human and animal models.Inflamm Bowel Dis. 2016;22(5):1137-1150. doi:10.1097/MIB.0000000000000750

Belizário JE, Faintuch J.Microbiome and gut dysbiosis.Exp Suppl. 2018;109:459-476. doi:10.1007/978-3-319-74932-7_13

Zhang L, Hu Y, Xu Y, et al.The correlation between intestinal dysbiosis and the development of ankylosing spondylitis.Microb Pathog. 2019;132:188-192. doi:10.1016/j.micpath.2019.04.038

Lee SY, Lee E, Park YM, Hong SJ.Microbiome in the gut-skin axis in atopic dermatitis.Allergy Asthma Immunol Res. 2018;10(4):354–362. doi:10.4168/aair.2018.10.4.354

Horta-Baas G, Romero-Figueroa MDS, Montiel-Jarquín AJ, Pizano-Zárate ML, García-Mena J, Ramírez-Durán N.Intestinal dysbiosis and rheumatoid arthritis: A link between gut microbiota and the pathogenesis of rheumatoid arthritis.J Immunol Res. 2017;2017:4835189. doi:10.1155/2017/4835189

Engen PA, Green SJ, Voigt RM, Forsyth CB, Keshavarzian A.The gastrointestinal microbiome: Alcohol effects on the composition of intestinal microbiota.Alcohol Res. 2015;37(2):223–236.

Rea K, Dinan TG, Cryan JF.The microbiome: A key regulator of stress and neuroinflammation.Neurobiol Stress. 2016;4:23–33. doi:10.1016/j.ynstr.2016.03.001

Wei L, Singh R, Ro S, Ghoshal UC.Gut microbiota dysbiosis in functional gastrointestinal disorders: Underpinning the symptoms and pathophysiology.JGH Open. 2021;5(9):976-987. doi:10.1002/jgh3.12528

Martinez JE, Kahana DD, Ghuman S, et al.Unhealthy lifestyle and gut dysbiosis: a better understanding of the effects of poor diet and nicotine on the intestinal microbiome.Front Endocrinol. 2021;12:649. doi:10.3389/fendo.2021.667066

Bull, M. & Plummer, N.Part 2: Treatments for chronic gastrointestinal disease and gut dysbiosis.Integrative Medicine: A Clinician’s Journal.2015;14:25–33.

Wang X, Zhang P, Zhang X.Probiotics regulate gut microbiota: an effective method to improve immunity.Molecules. 2021;26(19):6076. doi:10.3390/molecules26196076

Chang C.Short-course therapy for diarrhea-predominant irritable bowel syndrome: understanding the mechanism, impact on gut microbiota, and safety and tolerability of rifaximin.Clin Exp Gastroenterol. 2018;11:335–345. Published 2018 Sep 24. doi:10.2147/CEG.S167031

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