Our body’s electrolytes are certain elements that arevital to life. They affect us in profound ways. Everything from generation of a brain cell’s energy to a nerve cell’s electricity, from our body’s water content to our heart’s rhythm, and more, is dependent on electrolytes like sodium, potassium, calcium, magnesium, and others being in a certain range (and you thought that an electrolyte is something you take to relieve a cramp!). In fact, life as we know it, would not exist without these elements which are an intricate part of our physiology.
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Let’s delve into an even deeper territory to understand why our existence would not have been possible without these electrolytes. These seemingly simple elements are in fact the bridge that connects us to the very birth of our universe. Confused? Well, here is a simple explanation. What we call electrolytes are essential elements (like sodium, potassium, or magnesium) that came into existence during the dawn of the universe.
Electrolytes and the Kidney
Let’s examine electrolytes and their disorders from a much more mundane perspective. Electrolyte abnormalities are very common inkidney diseasestates for one simple reason—it is the kidney that typically has a central role in maintaining normal levels of most electrolytes. Therefore, these abnormalities are a consequence of abnormal kidney function, rather than a cause.
Both low and high levels of electrolytes can be seen when the kidneys malfunction, but can have a multitude of other indirect causes. The finer details of every possible cause and its respective treatment is beyond the scope of this article. However, here is a brief overview of issues related to abnormal sodium levels.
A State of Low Sodium Level, or Hyponatremia
Typically, a sodium level in the blood of less than 135 meq/L is considered abnormal and calledhyponatremia. Two major determinants of the sodium level in the blood are, (a) the amount of sodium in the blood, and (b) the amount of water in the blood. In many disease states, a low sodium level is not a problem of lack of sodium, but in fact anexcess of waterfor the amount of sodium (which ends up effectively diluting the sodium content).
Remember, when we measure sodium level in the blood, it is not theabsoluteamount of sodium, but in fact itsconcentrationthat we look at. Which means the water content of the blood will impact sodium concentration as well. Understanding this concept is essential to realizing why sodium falls in certain disease states, and why the treatment is not always to “eat more salt/sodium.”
Some of the common causes of low sodium levels are as follows (this is not an exhaustive list):
Treatment of Hyponatremia
Once a low sodium level has been confirmed on blood testing, treatment will depend on what is the cause of low sodium, and even how quickly it has developed. For instance, in states of excess water in the body (like congestive heart failure or SIADH), water restriction or strategies geared towards promoting water excretion from the body are instituted. On the other hand, in states where there is an actual deficit of salt/sodium in the body, replacing the sodium in the form of salt tablets or as part of IV fluids is recommended. A rapid correction could be dangerous, especially when hyponatremia has persisted for a while.
A Case of Too High Sodium Level, or Hypernatremia
A blood level of sodium higher than 145 meq/L is referred to as “hypernatremia”. The most common cause of hypernatremia is an elevation in sodium created because of adeficit of water.Hence, disease states associated with dehydration, or increased water loss from the body (like diabetes insipidus) can cause hypernatremia. The average person typically starts to get a strong sensation of thirst when sodium levels begin to go up in the blood. As long as they have access to water, the sodium level should come down. The problem, however, arises if people do not have access to water, or if they lose too much water from the kidneys or the gut, or if they cannot sense thirst (as can happen in elderly patients). Since most hypernatremia states involve dehydration, treatment strategies include administration of water-rich IV fluids or oral intake of water.
Here as some of the common causes of high sodium level in the blood:
What Effect Does High or Low Sodium Have on You?
Symptoms of abnormal sodium levels depend on the severity of the abnormality, and the rapidity of its development. They can range from mild symptoms like a headache to more severe ones like gait abnormalities, cramps, heart rhythm changes, etc. One dreaded complication of excessively low sodium level is the risk ofseizures. Hence, timely treatment is necessary.
4 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Langston C.Managing Fluid and Electrolyte Disorders in Kidney Disease.Vet Clin North Am Small Anim Pract. 2017;47(2):471-490. doi:10.1016/j.cvsm.2016.09.011Hoorn EJ, Zietse R.Diagnosis and Treatment of Hyponatremia: Compilation of the Guidelines.J Am Soc Nephrol. 2017;28(5):1340-1349. doi:10.1681/ASN.2016101139Muhsin SA, Mount DB.Diagnosis and treatment of hypernatremia.Best Pract Res Clin Endocrinol Metab.2016;30(2):189-203. doi:10.1016/j.beem.2016.02.014Halawa I, Andersson T, Tomson T.Hyponatremia and risk of seizures: a retrospective cross-sectional study.Epilepsia. 2011;52(2):410-3. doi:10.1111/j.1528-1167.2010.02939.x
4 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Langston C.Managing Fluid and Electrolyte Disorders in Kidney Disease.Vet Clin North Am Small Anim Pract. 2017;47(2):471-490. doi:10.1016/j.cvsm.2016.09.011Hoorn EJ, Zietse R.Diagnosis and Treatment of Hyponatremia: Compilation of the Guidelines.J Am Soc Nephrol. 2017;28(5):1340-1349. doi:10.1681/ASN.2016101139Muhsin SA, Mount DB.Diagnosis and treatment of hypernatremia.Best Pract Res Clin Endocrinol Metab.2016;30(2):189-203. doi:10.1016/j.beem.2016.02.014Halawa I, Andersson T, Tomson T.Hyponatremia and risk of seizures: a retrospective cross-sectional study.Epilepsia. 2011;52(2):410-3. doi:10.1111/j.1528-1167.2010.02939.x
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Langston C.Managing Fluid and Electrolyte Disorders in Kidney Disease.Vet Clin North Am Small Anim Pract. 2017;47(2):471-490. doi:10.1016/j.cvsm.2016.09.011Hoorn EJ, Zietse R.Diagnosis and Treatment of Hyponatremia: Compilation of the Guidelines.J Am Soc Nephrol. 2017;28(5):1340-1349. doi:10.1681/ASN.2016101139Muhsin SA, Mount DB.Diagnosis and treatment of hypernatremia.Best Pract Res Clin Endocrinol Metab.2016;30(2):189-203. doi:10.1016/j.beem.2016.02.014Halawa I, Andersson T, Tomson T.Hyponatremia and risk of seizures: a retrospective cross-sectional study.Epilepsia. 2011;52(2):410-3. doi:10.1111/j.1528-1167.2010.02939.x
Langston C.Managing Fluid and Electrolyte Disorders in Kidney Disease.Vet Clin North Am Small Anim Pract. 2017;47(2):471-490. doi:10.1016/j.cvsm.2016.09.011
Hoorn EJ, Zietse R.Diagnosis and Treatment of Hyponatremia: Compilation of the Guidelines.J Am Soc Nephrol. 2017;28(5):1340-1349. doi:10.1681/ASN.2016101139
Muhsin SA, Mount DB.Diagnosis and treatment of hypernatremia.Best Pract Res Clin Endocrinol Metab.2016;30(2):189-203. doi:10.1016/j.beem.2016.02.014
Halawa I, Andersson T, Tomson T.Hyponatremia and risk of seizures: a retrospective cross-sectional study.Epilepsia. 2011;52(2):410-3. doi:10.1111/j.1528-1167.2010.02939.x
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