Aging is an inevitable result of living, andwrinklesare a sign of aging. Collagen in the dermis is made up of fibers of protein that, along with elastin, give strength, support, and resilience to the skin. Collagen production starts to slow down as early as a person’s 30s.
The strands break up and decrease in number and elongate. This, along with hyperactive facial muscles, sun damage, and years of tobacco use all contribute to wrinkle formation.
There’s nothing wrong with wrinkles, and some people view their wrinkles as evidence of a full life. They don’t mind wrinkles and don’t want to spend money or time smoothing them out. Other people, however, desire torid themselves of wrinkles.
PhotoAlto / Frederic Cirou / Getty Images

In addition to certain lifestyle modifications, like avoiding sun exposure and smoking cessation, there are numerous non-invasive treatments for wrinkles, including laser, chemical peeling, tissue filler injections, and botulinum toxin injections (Botox, Daxxify, Dysport, Jeuveau, Letybo, and Xeomin).
Xeomin vs. Botox: Which Is Right for You?
Injection with botulinum works best with dynamic wrinkles or wrinkles that appear after the formation of facial expressions like a smile or a frown.
Conversely, static wrinkles remain while your face is relaxed and are best treated with a combination of botulinum toxin and dermal fillers. Static wrinkles are also treated commonly with chemical peels, microdermabrasion, radiofrequency micro-needling, and laser resurfacing.
1:286 Tips for Preventing Wrinkles
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6 Tips for Preventing Wrinkles
1Glabellar LinesMotortion / Getty ImagesThe glabella is a patch of skin between the eyebrows and above the nose. Treatment of glabellar lines is the most common cosmetic use of botulinum toxin.2Crow’s-FeetVeronique Beranger / Getty ImagesCrow’s-feet(also called periorbital lines or lateral canthal lines) are wrinkles that branch from the outer corners of the eyes while smiling. Of note, crow’s-feet that are staticthus occur in both the presence and absence of smiling.Crow’s-feet are the second most frequent types of wrinkles treated with Botox Cosmetic, which works beautifully with the dynamic wrinkles in this area.3Forehead WrinklesFrederick Bass / Getty ImagesThe relatively large facial muscle that overlies the forehead is called the frontalis muscle. When the frontalis muscle contracts, the brow raises and forehead lines appear.4Bunny LinesNico Kai / Getty ImagesBunny lines occur on the bridge of the nose. They can become more prominent after botulinum toxin treatment for glabellar lines or crow’s feet. Thus, people who have Botox treatment for glabellar lines or crow’s feet often return for treatment of bunny lines, too.5Lipstick LinesSimon Winnall / Getty ImagesPerioral or lipstick lines are vertical wrinkles above the upper lip. The formation of lipstick lines is likely multifactorial andphotoaging, hereditary factors, puckering, and smoking all contribute.6Marionette LinesWestend61/Getty ImagesMarionette lines are vertical wrinkles that originate at the corners of the mouth and branch downwards towards the chin. (These lines resemble the borders of the jaw segment of a marionette.) Marionette lines are usually treated withdermal fillersor a facelift.7Chin DimplingTim Flach/Getty ImagesChin dimpling gives the chin an orange-peel (peau d’orange) appearance. As with the treatment of marionette lines, smoothing chin dimples often requires both botulinum toxin and dermal fillers.How to Choose a Facial Filler
1Glabellar LinesMotortion / Getty ImagesThe glabella is a patch of skin between the eyebrows and above the nose. Treatment of glabellar lines is the most common cosmetic use of botulinum toxin.
1
Glabellar LinesMotortion / Getty ImagesThe glabella is a patch of skin between the eyebrows and above the nose. Treatment of glabellar lines is the most common cosmetic use of botulinum toxin.
Glabellar Lines
Motortion / Getty Images

The glabella is a patch of skin between the eyebrows and above the nose. Treatment of glabellar lines is the most common cosmetic use of botulinum toxin.
2Crow’s-FeetVeronique Beranger / Getty ImagesCrow’s-feet(also called periorbital lines or lateral canthal lines) are wrinkles that branch from the outer corners of the eyes while smiling. Of note, crow’s-feet that are staticthus occur in both the presence and absence of smiling.Crow’s-feet are the second most frequent types of wrinkles treated with Botox Cosmetic, which works beautifully with the dynamic wrinkles in this area.
2
Crow’s-FeetVeronique Beranger / Getty ImagesCrow’s-feet(also called periorbital lines or lateral canthal lines) are wrinkles that branch from the outer corners of the eyes while smiling. Of note, crow’s-feet that are staticthus occur in both the presence and absence of smiling.Crow’s-feet are the second most frequent types of wrinkles treated with Botox Cosmetic, which works beautifully with the dynamic wrinkles in this area.
Crow’s-Feet
Veronique Beranger / Getty Images

Crow’s-feet(also called periorbital lines or lateral canthal lines) are wrinkles that branch from the outer corners of the eyes while smiling. Of note, crow’s-feet that are staticthus occur in both the presence and absence of smiling.
Crow’s-feet are the second most frequent types of wrinkles treated with Botox Cosmetic, which works beautifully with the dynamic wrinkles in this area.
3Forehead WrinklesFrederick Bass / Getty ImagesThe relatively large facial muscle that overlies the forehead is called the frontalis muscle. When the frontalis muscle contracts, the brow raises and forehead lines appear.
3
Forehead WrinklesFrederick Bass / Getty ImagesThe relatively large facial muscle that overlies the forehead is called the frontalis muscle. When the frontalis muscle contracts, the brow raises and forehead lines appear.
Forehead Wrinkles
Frederick Bass / Getty Images

The relatively large facial muscle that overlies the forehead is called the frontalis muscle. When the frontalis muscle contracts, the brow raises and forehead lines appear.
4Bunny LinesNico Kai / Getty ImagesBunny lines occur on the bridge of the nose. They can become more prominent after botulinum toxin treatment for glabellar lines or crow’s feet. Thus, people who have Botox treatment for glabellar lines or crow’s feet often return for treatment of bunny lines, too.
4
Bunny LinesNico Kai / Getty ImagesBunny lines occur on the bridge of the nose. They can become more prominent after botulinum toxin treatment for glabellar lines or crow’s feet. Thus, people who have Botox treatment for glabellar lines or crow’s feet often return for treatment of bunny lines, too.
Bunny Lines
Nico Kai / Getty Images

Bunny lines occur on the bridge of the nose. They can become more prominent after botulinum toxin treatment for glabellar lines or crow’s feet. Thus, people who have Botox treatment for glabellar lines or crow’s feet often return for treatment of bunny lines, too.
5Lipstick LinesSimon Winnall / Getty ImagesPerioral or lipstick lines are vertical wrinkles above the upper lip. The formation of lipstick lines is likely multifactorial andphotoaging, hereditary factors, puckering, and smoking all contribute.
5
Lipstick LinesSimon Winnall / Getty ImagesPerioral or lipstick lines are vertical wrinkles above the upper lip. The formation of lipstick lines is likely multifactorial andphotoaging, hereditary factors, puckering, and smoking all contribute.
Lipstick Lines
Simon Winnall / Getty Images

Perioral or lipstick lines are vertical wrinkles above the upper lip. The formation of lipstick lines is likely multifactorial andphotoaging, hereditary factors, puckering, and smoking all contribute.
6Marionette LinesWestend61/Getty ImagesMarionette lines are vertical wrinkles that originate at the corners of the mouth and branch downwards towards the chin. (These lines resemble the borders of the jaw segment of a marionette.) Marionette lines are usually treated withdermal fillersor a facelift.
6
Marionette LinesWestend61/Getty ImagesMarionette lines are vertical wrinkles that originate at the corners of the mouth and branch downwards towards the chin. (These lines resemble the borders of the jaw segment of a marionette.) Marionette lines are usually treated withdermal fillersor a facelift.
Marionette Lines
Westend61/Getty Images

Marionette lines are vertical wrinkles that originate at the corners of the mouth and branch downwards towards the chin. (These lines resemble the borders of the jaw segment of a marionette.) Marionette lines are usually treated withdermal fillersor a facelift.
7Chin DimplingTim Flach/Getty ImagesChin dimpling gives the chin an orange-peel (peau d’orange) appearance. As with the treatment of marionette lines, smoothing chin dimples often requires both botulinum toxin and dermal fillers.How to Choose a Facial Filler
7
Chin DimplingTim Flach/Getty ImagesChin dimpling gives the chin an orange-peel (peau d’orange) appearance. As with the treatment of marionette lines, smoothing chin dimples often requires both botulinum toxin and dermal fillers.How to Choose a Facial Filler
Chin Dimpling
Tim Flach/Getty Images

Chin dimpling gives the chin an orange-peel (peau d’orange) appearance. As with the treatment of marionette lines, smoothing chin dimples often requires both botulinum toxin and dermal fillers.
How to Choose a Facial Filler
A Word From VerywellMost people who receive botulinum toxin injections are pretty happy with the results and go on to purchase more injections. However, treatment with such agents is a temporary measure with lines returning after about four to six months.Furthermore, as with all medical treatments, treatment with Botox carries its own risks of adverse effects (mostly short-lived) including swelling, muscle weakness, and pain. For instance, Nicole Kidman famously toldLa Republica, “I did try Botox, unfortunately, but I got out of it and now I can finally move my face again.“If you’re interested in Botox, please make an appointment with a specialist for an evaluation and to discuss your options.
A Word From Verywell
Most people who receive botulinum toxin injections are pretty happy with the results and go on to purchase more injections. However, treatment with such agents is a temporary measure with lines returning after about four to six months.
Furthermore, as with all medical treatments, treatment with Botox carries its own risks of adverse effects (mostly short-lived) including swelling, muscle weakness, and pain. For instance, Nicole Kidman famously toldLa Republica, “I did try Botox, unfortunately, but I got out of it and now I can finally move my face again.”
If you’re interested in Botox, please make an appointment with a specialist for an evaluation and to discuss your options.
2 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Small R.Botulinum toxin injection for facial wrinkles.Am Fam Physician. 2014;90(3):168-75.De boulle K, Fagien S, Sommer B, Glogau R.Treating glabellar lines with botulinum toxin type A-hemagglutinin complex: a review of the science, the clinical data, and patient satisfaction.Clin Interv Aging. 2010;5:101-18. doi:10.2147/cia.s9338Additional ReadingCamargo CPires, Costa CS, Gemperli R, Tatini MDC, Bulsara MK, Riera R.Botulinum toxin for facial wrinkles.Cochrane Database of Systematic Reviews2014;9:CD011301. doi:10.1002/14651858.CD011301Dorizas A, Krueger N, Sadick NS.Aesthetic uses of the botulinum toxin.Dermatol Clin. 2014;32(1):23-36. doi:10.1016/j.det.2013.09.009
2 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Small R.Botulinum toxin injection for facial wrinkles.Am Fam Physician. 2014;90(3):168-75.De boulle K, Fagien S, Sommer B, Glogau R.Treating glabellar lines with botulinum toxin type A-hemagglutinin complex: a review of the science, the clinical data, and patient satisfaction.Clin Interv Aging. 2010;5:101-18. doi:10.2147/cia.s9338Additional ReadingCamargo CPires, Costa CS, Gemperli R, Tatini MDC, Bulsara MK, Riera R.Botulinum toxin for facial wrinkles.Cochrane Database of Systematic Reviews2014;9:CD011301. doi:10.1002/14651858.CD011301Dorizas A, Krueger N, Sadick NS.Aesthetic uses of the botulinum toxin.Dermatol Clin. 2014;32(1):23-36. doi:10.1016/j.det.2013.09.009
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Small R.Botulinum toxin injection for facial wrinkles.Am Fam Physician. 2014;90(3):168-75.De boulle K, Fagien S, Sommer B, Glogau R.Treating glabellar lines with botulinum toxin type A-hemagglutinin complex: a review of the science, the clinical data, and patient satisfaction.Clin Interv Aging. 2010;5:101-18. doi:10.2147/cia.s9338
Small R.Botulinum toxin injection for facial wrinkles.Am Fam Physician. 2014;90(3):168-75.
De boulle K, Fagien S, Sommer B, Glogau R.Treating glabellar lines with botulinum toxin type A-hemagglutinin complex: a review of the science, the clinical data, and patient satisfaction.Clin Interv Aging. 2010;5:101-18. doi:10.2147/cia.s9338
Camargo CPires, Costa CS, Gemperli R, Tatini MDC, Bulsara MK, Riera R.Botulinum toxin for facial wrinkles.Cochrane Database of Systematic Reviews2014;9:CD011301. doi:10.1002/14651858.CD011301Dorizas A, Krueger N, Sadick NS.Aesthetic uses of the botulinum toxin.Dermatol Clin. 2014;32(1):23-36. doi:10.1016/j.det.2013.09.009
Camargo CPires, Costa CS, Gemperli R, Tatini MDC, Bulsara MK, Riera R.Botulinum toxin for facial wrinkles.Cochrane Database of Systematic Reviews2014;9:CD011301. doi:10.1002/14651858.CD011301
Dorizas A, Krueger N, Sadick NS.Aesthetic uses of the botulinum toxin.Dermatol Clin. 2014;32(1):23-36. doi:10.1016/j.det.2013.09.009
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