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Table of Contents

Overview

How Common

By Ethnicity

By Age and Sex

Causes

Mortality

Screening and Early Detection

Next in Hodgkin Lymphoma Guide

In 2022, it was estimated that about 8,540 people in the United States would be diagnosed withHodgkin lymphomaand more than 900 would die of the disease that year.Hodgkin lymphoma is a cancer of the lymphatic system.The survival rate has increased consistently since 1975.

This article will present facts and statistics you should know about Hodgkin lymphoma.

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Person feeling swollen lymph nodes in neck, which can be a sign of Hodgkin lymphoma

Hodgkin Lymphoma Overview

Hodgkin lymphoma, also called Hodgkin’s disease, is a type of lymphoma.Lymphomais cancer of thelymphatic system, which helps to fight disease and infection.

There are different types of Hodgkin lymphoma. Knowing the specific type is important because this determines the treatment.

Classic Hodgkin lymphoma includes these subtypes:

Nodular lymphocyte-predominant Hodgkin lymphoma is a rare subtype. It is seen in about 5% of people with Hodgkin lymphoma.

How Common Is Hodgkin Lymphoma?

According to the National Cancer Institute, it was predicted that in 2022, there would be approximately 8,540 new cases of Hodgkin lymphoma and about 920 deaths.From 2010 to 2019, the number of diagnoses had decreased each year.Hodgkin lymphoma is diagnosed in about 2.6 out of every 100,000 people.

Although cancer can affect everyone, statistics often are also broken down into race/ethnicity because there can be genetic associations in the condition ordisparitiesin diagnosis and/or survival due to access to health care, systemic racism, and other issues.

The average annual rate of diagnosis of Hodgkin lymphoma per 100,000 people in the United States is:

Although Hodgkin lymphoma can affect both children and adults, it’s most common in two age groups:

The average age of diagnosis is 39.It’s rare in those under 5, but in teens 15 to 19, it’s the most commonly diagnosed cancer.

Overall, more males than females are diagnosed with Hodgkin lymphoma each year. Estimated new cases for 2022 were:

Causes of Hodgkin Lymphoma

Approximately 25% of those with classic Hodgkin lymphoma have lymphoma cells testing positive for EBV.The exact association is not known, though, because while most adults in the United States have been infected with EBV, most adults do not develop Hodgkin lymphoma.

Other risk factors can include:

What Are the Mortality Rates for Hodgkin Lymphoma?

It was predicted that about about 550 males and 370 females would die from Hodgkin lymphoma in 2022. The survival rate has been increasing since 1975 due to better treatments.

Prognosis and five-year survival rates also depend on the stage (how much cancer there is and how far the cancer has spread):

Overall, there is a five-year survival rate for Hodgkin lymphoma of 88% in the United States.

What Is “Survival Rate”?The term “survival rate” is the percentage of people who are still living with a disease (like lymphoma) for a certain amount of time. For cancer, thesurvival rateis usually presented as a five-year survival rate and includes the percentage of people alive five years after diagnosis.The five-year survival rate cannot predict how an individual will respond to treatment, and it does not reflect advancements in treatment made in the past five years.

What Is “Survival Rate”?

The term “survival rate” is the percentage of people who are still living with a disease (like lymphoma) for a certain amount of time. For cancer, thesurvival rateis usually presented as a five-year survival rate and includes the percentage of people alive five years after diagnosis.The five-year survival rate cannot predict how an individual will respond to treatment, and it does not reflect advancements in treatment made in the past five years.

The term “survival rate” is the percentage of people who are still living with a disease (like lymphoma) for a certain amount of time. For cancer, thesurvival rateis usually presented as a five-year survival rate and includes the percentage of people alive five years after diagnosis.

The five-year survival rate cannot predict how an individual will respond to treatment, and it does not reflect advancements in treatment made in the past five years.

There are no general, regular screenings for Hodgkin lymphoma. Many people start experiencing symptoms and then see a healthcare provider to find out the cause.

A complete medical history and physical exam will be done. The healthcare provider will ask questions about symptoms you may be experiencing.

Todiagnose Hodgkin lymphoma, a biopsy of a lymph node must be done.This involves removing alymph node(or part of one) and analyzing it in the lab. Other tests that may be done to determine the stage of disease and other characteristics of the cancer include:

Summary

Hodgkin lymphoma is a cancer of the lymphatic system, which helps the body fight infection and disease. The cause is not definitively known, but the Epstein-Barr virus may be a factor. There have been many improvements in treatment in the last few decades, which has resulted in improved overall survival.

There are no regular screening tools for this cancer. Many times, a person won’t be diagnosed until they start having persistent symptoms and see a healthcare provider.

8 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Munir F, Hardit V, Sheikh IN, et al.Classical Hodgkin Lymphoma: From Past to Future-A Comprehensive Review of Pathophysiology and Therapeutic Advances.Int J Mol Sci. 2023;24(12):10095. Published 2023 Jun 13. doi:10.3390/ijms241210095National Cancer Institute.Lymphoma.Leukemia & Lymphoma Society.Hodgkin lymphoma subtypes.National Cancer Institute.Cancer stat facts: Hodgkin lymphoma.American Cancer Society Cancer Statistics Center.Incidence rates, 2014-2018.American Cancer Society Cancer Statistics Center.Hodgkin lymphoma at a glance.American Cancer Society.Hodgkin lymphoma risk factors.Wang HW, Balakrishna JP, Pittaluga S, Jaffe ES.Diagnosis of Hodgkin lymphoma in the modern era.Br J Haematol. 2019;184(1):45-59. doi:10.1111/bjh.15614

8 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Munir F, Hardit V, Sheikh IN, et al.Classical Hodgkin Lymphoma: From Past to Future-A Comprehensive Review of Pathophysiology and Therapeutic Advances.Int J Mol Sci. 2023;24(12):10095. Published 2023 Jun 13. doi:10.3390/ijms241210095National Cancer Institute.Lymphoma.Leukemia & Lymphoma Society.Hodgkin lymphoma subtypes.National Cancer Institute.Cancer stat facts: Hodgkin lymphoma.American Cancer Society Cancer Statistics Center.Incidence rates, 2014-2018.American Cancer Society Cancer Statistics Center.Hodgkin lymphoma at a glance.American Cancer Society.Hodgkin lymphoma risk factors.Wang HW, Balakrishna JP, Pittaluga S, Jaffe ES.Diagnosis of Hodgkin lymphoma in the modern era.Br J Haematol. 2019;184(1):45-59. doi:10.1111/bjh.15614

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Munir F, Hardit V, Sheikh IN, et al.Classical Hodgkin Lymphoma: From Past to Future-A Comprehensive Review of Pathophysiology and Therapeutic Advances.Int J Mol Sci. 2023;24(12):10095. Published 2023 Jun 13. doi:10.3390/ijms241210095National Cancer Institute.Lymphoma.Leukemia & Lymphoma Society.Hodgkin lymphoma subtypes.National Cancer Institute.Cancer stat facts: Hodgkin lymphoma.American Cancer Society Cancer Statistics Center.Incidence rates, 2014-2018.American Cancer Society Cancer Statistics Center.Hodgkin lymphoma at a glance.American Cancer Society.Hodgkin lymphoma risk factors.Wang HW, Balakrishna JP, Pittaluga S, Jaffe ES.Diagnosis of Hodgkin lymphoma in the modern era.Br J Haematol. 2019;184(1):45-59. doi:10.1111/bjh.15614

Munir F, Hardit V, Sheikh IN, et al.Classical Hodgkin Lymphoma: From Past to Future-A Comprehensive Review of Pathophysiology and Therapeutic Advances.Int J Mol Sci. 2023;24(12):10095. Published 2023 Jun 13. doi:10.3390/ijms241210095

National Cancer Institute.Lymphoma.

Leukemia & Lymphoma Society.Hodgkin lymphoma subtypes.

National Cancer Institute.Cancer stat facts: Hodgkin lymphoma.

American Cancer Society Cancer Statistics Center.Incidence rates, 2014-2018.

American Cancer Society Cancer Statistics Center.Hodgkin lymphoma at a glance.

American Cancer Society.Hodgkin lymphoma risk factors.

Wang HW, Balakrishna JP, Pittaluga S, Jaffe ES.Diagnosis of Hodgkin lymphoma in the modern era.Br J Haematol. 2019;184(1):45-59. doi:10.1111/bjh.15614

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