How Much Vitamin C Do You Need Per Day for Immunity and Wellness?

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Table of Contents

Vitamin C Goals

Who Needs Vitamin C?

Can You Get Too Much?

Food vs. Supplements

Foods High in It

Choosing Supplements

Other Benefits

Vitamin C is a water-soluble vitamin needed for essential body processes. The human body does not make or store vitamin C, and it eliminates any excess in the urine. You must get enough vitamin C daily from food or supplements.

You need to get enough vitamin C to support your immune health and other body functions. However, most people do not needvitamin C supplementationbecause they get enough in food and drinks.

The amount of vitamin C you need will depend on your age and the amount of vitamin C you can get from your diet.

The National Institutes of Health (NIH) recommends the following doses of vitamin C daily:

Within the NIH ranges, males need higher amounts of vitamin C. If you are pregnant or lactating, you will also need higher amounts. If you are pregnant, it is not a good idea to take vitamin C supplements without first talking to a healthcare provider.

People who smoke have higher vitamin C needs. The NIH recommends an additional 35 mg of the vitamin if you are a smoker.

How Much Vitamin C Do You Need for Specific Goals?

Vitamin C is known for boosting immunity and reducingoxidative stress(an imbalance between antioxidants and damaging free radicals in cells). It also has other health benefits.

Boosting Immunity

One of the main reasons for taking vitamin C supplements is to boost immunity, as vitamin C can be vital to various areas of the immune system.

Ways in which vitamin C canboost the immune systeminclude:

Low levels of vitamin C are linked to poor health outcomes. Research shows that low vitamin C can put people at risk forinflammatory conditions.

Reducing Cancer Risk

Some research suggests that vitamin C intake in foods may reduce the risk of some cancer types. A 2021Antioxidantsreview finds that consuming vitamin C from foods could potentially decrease the risk of pancreatic, breast, and pulmonary cancers. Still, more research is needed to confirm such findings.

The same report also suggests that vitamin C, already used as acomplementary cancer therapy, can be administered in high doses to treat certain cancers. Research on safety and efficacy in this area is ongoing.

The National Cancer Institute (NCI) reports some healthcare practitioners already use intravenous (IV) vitamin C to treat cancer,fatigue, and infections.According to the NCI, IV administration of vitamin C in doses of over 500 mg produces a higher blood concentration of ascorbate (a biologically active form of vitamin C) than oral supplementation.

Lowering Risk for Metabolic Syndrome

Vitamin C may help lower your risk for conditions associated withmetabolic syndrome.Metabolic syndrome is a cluster of three or more conditions that increase the risk of heart attack, stroke, and diabetes. These conditions include high blood pressure, high blood sugar,abdominal obesity, high triglyceride levels, and low high-density lipoprotein (HDL) cholesterol (considered “good” cholesterol).

Research on vitamin C supplementation has shown reduced risk and improved conditions.The dosing for such studies falls between 100 mg and 150 mg.

Improving Cardiovascular Health

According to a 2020 review, Vitamin C has positive effects oncardiovascular healthand blood flow.While the effects of vitamin C on heart health are promising, the authors note that more research is needed to confirm whether vitamin C alone can prevent cardiovascular disease.

Most clinical studies recommend 500 to 1,000 mg of vitamin C daily for heart health.The NIH’s daily recommendations are much lower, at 75 mg to 90 mg.

Managing Blood Pressure

Studies have found that vitamin C may help to lower blood pressure in both people with hypertension (high blood pressure) and people without the condition.

One 2024 study aimed to evaluate the effect of a vitamin C supplement (130 mg) with a beverage containing 278.7 mg of flavonoids.

Reducing Uric Acid

A 2021 study found a strong link between vitamin C supplementation and decreased uric acid levels.In this study, a 500 mg daily vitamin C intake reduced uric acid levels.

While the researchers found the findings promising, they did not feel there was enough evidence to recommend vitamin C supplementation as a method of gout prevention or treatment.

Preventing Iron Deficiency

If you have aniron deficiency, your body does not have enough iron to produce the hemoglobin inred blood cellsthat carries oxygen to your organs and tissues. Vitamin C can improve iron absorption.

One 2020 clinical trial examined the effect of oral iron supplements and iron supplements in combination with vitamin C on treatingiron deficiency anemia. It found that combining iron and vitamin C improvedhemoglobinlevels much better than treating with iron alone.

The dosing in this study was 100 mg iron and 200 mg vitamin C.

Promoting Eye Health

Some research suggests that vitamin C may reduce the risk ofage-related macular degeneration(AMD). According to the American Academy of Ophthalmology, 500 mg of vitamin C, combined with vitamin E, zinc, copper, lutein, and zeaxanthin, may decrease the risk for AMD.

The Health Benefits of Vitamin C

Who Might Especially Benefit From Vitamin C?

Research shows that some people may benefit from a higher vitamin C intake. This includes:

Additional health factors can affect a person’s vitamin C status.These include:

How To Boost Your Vitamin D Levels During Cold and Flu Season

Can You Get Too Much Vitamin C?

Vitamin Ctoxicityis rare.The most common side effect of high vitamin C is gastrointestinal (GI) distress.

GI symptoms from too much vitamin C include diarrhea, abdominal pain, nausea, and vomiting. High amounts of vitamin C may also cause headaches. If you experience these symptoms after a high vitamin C dose, cutting back or stopping supplementation can help you feel better.

How Much Is Too Much?

If you take more than 2,000 mg of vitamin C at once, you will most likely experience digestive symptoms.GI side effects and headaches are commonly seen in people who take high doses of vitamin C supplements.

Food vs. Supplements: Which Source Is Better?

Many foods contain vitamin C, especially fruits and vegetables. You can get the recommended amounts of vitamin C from food if you are eating a balanced diet.

For most people, getting their vitamin C from food is better than taking supplements.If you are getting enough vitamin C from your diet, you likely will not need to supplement.

The Best Time to Take Vitamin C Supplements, According to Science

Top Foods Packed With Vitamin C

All fruits and vegetables contain vitamin C. Raw fruits and vegetables are the best sources of vitamin C.Cooking vitamin-rich foods or storing them for long periods can reduce their amount of vitamin C.

Fruits with the highest amounts of vitamin C include:

Vegetables from the highest amounts of vitamin C include:

Various cereals, foods, and beverages are fortified with vitamin C. This means that vitamin C has been added to them. Check product labels to see which foods and beverages are vitamin C fortified.

27 High Vitamin C Foods

What to Look for in a Vitamin C Supplement

When purchasing vitamin C supplements, consider their quality, price, form, and packaging:

What Is Airless Delivery?Airless delivery in medicine refers to a system in which drug formulations are not in contact with air.This protects them from oxygen, light, moisture, and dirt and ensures stability and shelf life.

What Is Airless Delivery?

Airless delivery in medicine refers to a system in which drug formulations are not in contact with air.This protects them from oxygen, light, moisture, and dirt and ensures stability and shelf life.

How Do I Choose a Supplement?

Other Vitamin C Health Benefits

Some unproven claims include:

Summary

Vitamin C is a water-soluble vitamin found in certain foods and supplements. It has various health benefits, including boosting the immune system, lowering blood pressure, protecting against gout attacks, improving iron absorption, and reducing the risk of chronic diseases.

The amount of vitamin C you need will depend on your age and how much you can get from your diet. Supplements are a great and simple way to boost your intake if you are not getting enough vitamin C from your diet. Toxicity and overdose from vitamin C are rare but possible with doses higher than 2,000 mg.

The best way to get enough vitamin C is through your diet. The best food sources of vitamin C are fruits and vegetables. If you are getting enough vitamin C from your diet, you do not need to supplement.

27 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Office of Dietary Supplements.Vitamin C - fact sheet for health professionals.Office of Dietary Supplements.Vitamin C - consumer.Cerullo G, Negro M, Parimbelli M, et al.The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19.Front Immunol. 2020;11:574029. doi:10.3389/fimmu.2020.574029Huijskens MJ, Walczak M, Koller N, et al.Technical advance: ascorbic acid induces the development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells.J Leukoc Biol. 2014;96(6):1165-1175. doi:10.1189/jlb.1TA0214-121RRCarr AC, Maggini S.Vitamin C and immune function.Nutrients. 2017;9(11):1211. doi:10.3390/nu9111211Pullar J, Carr A, Vissers M.The roles of vitamin C in skin health.Nutrients. 2017;9(8):866. doi:10.3390/nu9080866Crook J, Horgas A, Yoon SJ, Grundmann O, Johnson-Mallard V.Insufficient vitamin C levels among adults in the United States: Results from the NHANES Surveys, 2003-2006. Nutrients. 2021;13(11):3910. Published 2021 Oct 30. doi:10.3390/nu13113910Villagran M, Ferreira J, Martorell M, Mardones L.The role of vitamin C in cancer prevention and therapy: a literature review.Antioxidants (Basel). 2021;10(12):1894. doi:10.3390/antiox10121894National Cancer Institute.Intravenous vitamin C (PDQ®)–health professional version.Wong SK, Chin KY, Ima-Nirwana S. Vitamin C:A review on its role in the management of metabolic syndrome.Int J Med Sci. 2020;17(11):1625-1638. doi:10.7150/ijms.47103Johns Hopkins Medicine.Metabolic syndrome.Morelli MB, Gambardella J, Castellanos V, Trimarco V, Santulli G.Vitamin C and cardiovascular disease: an update.Antioxidants (Basel). 2020;9(12):1227. doi:10.3390/antiox9121227Moser MA, Chun OK.Vitamin C and heart health: a review based on findings from epidemiologic studies. Int J Mol Sci. 2016;17(8):1328. doi:10.3390/ijms17081328Du W, Zhang S, Yang J, Fan H.Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.Asia Pac J Clin Nutr. 2024;33(4):503-514. doi:10.6133/apjcn.202412_33(4).0005Brzezińska O, Styrzyński F, Makowska J, Walczak K.Role of vitamin C in prophylaxis and treatment of gout—a literature review.Nutrients. 2021;13(2):701. doi:10.3390%2Fnu13020701Li N, Zhao G, Wu W, et al.The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: A randomized clinical trial.JAMA Netw Open. 2020;3(11):e2023644. Published 2020 Nov 2. doi:10.1001/jamanetworkopen.2020.23644American Academy of Ophthalmology.Vitamins for AMD,Lim JC, Caballero Arredondo M, Braakhuis AJ, Donaldson PJ.Vitamin C and the lens: new insights into delaying the onset of cataract.Nutrients. 2020;12(10):3142. doi:10.3390/nu12103142Carr AC, Rowe S.Factors affecting vitamin C status and prevalence of deficiency: a global health perspective.Nutrients. 2020;12(7):1963. doi:10.3390/nu12071963Aversa R, Petrescu RVV, Apicella A, Petrescu FIT.We are addicted to vitamins C and E-a review.Am. J. Eng. Appl. Sci. 2016;9(4):1003-1018. doi:10.3844/ajeassp.2016.1003.1018Lentjes MAH.The balance between food and dietary supplements in the general population.Proc Nutr Soc. 2019;78(1):97-109. doi:10.1017/S0029665118002525MedlinePlus.Vitamin C.My Food Data.Top 10 foods highest in vitamin C.Food and Drug Administration.Current Good Manufacturing Practices (CGMPs) for food and dietary supplements.Godoy HT, Amaya-Farfan J, Rodriguez-Amaya DB.Degradation of vitamins. Chemical changes during processing and storage of foods. 2021:329-383. doi:10.1016/b978-0-12-817380-0.00008-7Vargason AM, Anselmo AC, Mitragotri S.The evolution of commercial drug delivery technologies.Nat Biomed Eng. 2021;5(9):951-967. doi:10.1038/s41551-021-00698-Ghanwat G, Patil AJ, Patil J, Kshirsagar M, Sontakke A, Ayachit RK.Effect of Vitamin C supplementation on blood lead level, oxidative stress and antioxidant status of battery manufacturing workers of Western Maharashtra, India.J Clin Diagn Res. 2016;10(4):BC08-BC11. doi:10.7860/JCDR/2016/15968.7528

27 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Office of Dietary Supplements.Vitamin C - fact sheet for health professionals.Office of Dietary Supplements.Vitamin C - consumer.Cerullo G, Negro M, Parimbelli M, et al.The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19.Front Immunol. 2020;11:574029. doi:10.3389/fimmu.2020.574029Huijskens MJ, Walczak M, Koller N, et al.Technical advance: ascorbic acid induces the development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells.J Leukoc Biol. 2014;96(6):1165-1175. doi:10.1189/jlb.1TA0214-121RRCarr AC, Maggini S.Vitamin C and immune function.Nutrients. 2017;9(11):1211. doi:10.3390/nu9111211Pullar J, Carr A, Vissers M.The roles of vitamin C in skin health.Nutrients. 2017;9(8):866. doi:10.3390/nu9080866Crook J, Horgas A, Yoon SJ, Grundmann O, Johnson-Mallard V.Insufficient vitamin C levels among adults in the United States: Results from the NHANES Surveys, 2003-2006. Nutrients. 2021;13(11):3910. Published 2021 Oct 30. doi:10.3390/nu13113910Villagran M, Ferreira J, Martorell M, Mardones L.The role of vitamin C in cancer prevention and therapy: a literature review.Antioxidants (Basel). 2021;10(12):1894. doi:10.3390/antiox10121894National Cancer Institute.Intravenous vitamin C (PDQ®)–health professional version.Wong SK, Chin KY, Ima-Nirwana S. Vitamin C:A review on its role in the management of metabolic syndrome.Int J Med Sci. 2020;17(11):1625-1638. doi:10.7150/ijms.47103Johns Hopkins Medicine.Metabolic syndrome.Morelli MB, Gambardella J, Castellanos V, Trimarco V, Santulli G.Vitamin C and cardiovascular disease: an update.Antioxidants (Basel). 2020;9(12):1227. doi:10.3390/antiox9121227Moser MA, Chun OK.Vitamin C and heart health: a review based on findings from epidemiologic studies. Int J Mol Sci. 2016;17(8):1328. doi:10.3390/ijms17081328Du W, Zhang S, Yang J, Fan H.Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.Asia Pac J Clin Nutr. 2024;33(4):503-514. doi:10.6133/apjcn.202412_33(4).0005Brzezińska O, Styrzyński F, Makowska J, Walczak K.Role of vitamin C in prophylaxis and treatment of gout—a literature review.Nutrients. 2021;13(2):701. doi:10.3390%2Fnu13020701Li N, Zhao G, Wu W, et al.The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: A randomized clinical trial.JAMA Netw Open. 2020;3(11):e2023644. Published 2020 Nov 2. doi:10.1001/jamanetworkopen.2020.23644American Academy of Ophthalmology.Vitamins for AMD,Lim JC, Caballero Arredondo M, Braakhuis AJ, Donaldson PJ.Vitamin C and the lens: new insights into delaying the onset of cataract.Nutrients. 2020;12(10):3142. doi:10.3390/nu12103142Carr AC, Rowe S.Factors affecting vitamin C status and prevalence of deficiency: a global health perspective.Nutrients. 2020;12(7):1963. doi:10.3390/nu12071963Aversa R, Petrescu RVV, Apicella A, Petrescu FIT.We are addicted to vitamins C and E-a review.Am. J. Eng. Appl. Sci. 2016;9(4):1003-1018. doi:10.3844/ajeassp.2016.1003.1018Lentjes MAH.The balance between food and dietary supplements in the general population.Proc Nutr Soc. 2019;78(1):97-109. doi:10.1017/S0029665118002525MedlinePlus.Vitamin C.My Food Data.Top 10 foods highest in vitamin C.Food and Drug Administration.Current Good Manufacturing Practices (CGMPs) for food and dietary supplements.Godoy HT, Amaya-Farfan J, Rodriguez-Amaya DB.Degradation of vitamins. Chemical changes during processing and storage of foods. 2021:329-383. doi:10.1016/b978-0-12-817380-0.00008-7Vargason AM, Anselmo AC, Mitragotri S.The evolution of commercial drug delivery technologies.Nat Biomed Eng. 2021;5(9):951-967. doi:10.1038/s41551-021-00698-Ghanwat G, Patil AJ, Patil J, Kshirsagar M, Sontakke A, Ayachit RK.Effect of Vitamin C supplementation on blood lead level, oxidative stress and antioxidant status of battery manufacturing workers of Western Maharashtra, India.J Clin Diagn Res. 2016;10(4):BC08-BC11. doi:10.7860/JCDR/2016/15968.7528

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Office of Dietary Supplements.Vitamin C - fact sheet for health professionals.Office of Dietary Supplements.Vitamin C - consumer.Cerullo G, Negro M, Parimbelli M, et al.The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19.Front Immunol. 2020;11:574029. doi:10.3389/fimmu.2020.574029Huijskens MJ, Walczak M, Koller N, et al.Technical advance: ascorbic acid induces the development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells.J Leukoc Biol. 2014;96(6):1165-1175. doi:10.1189/jlb.1TA0214-121RRCarr AC, Maggini S.Vitamin C and immune function.Nutrients. 2017;9(11):1211. doi:10.3390/nu9111211Pullar J, Carr A, Vissers M.The roles of vitamin C in skin health.Nutrients. 2017;9(8):866. doi:10.3390/nu9080866Crook J, Horgas A, Yoon SJ, Grundmann O, Johnson-Mallard V.Insufficient vitamin C levels among adults in the United States: Results from the NHANES Surveys, 2003-2006. Nutrients. 2021;13(11):3910. Published 2021 Oct 30. doi:10.3390/nu13113910Villagran M, Ferreira J, Martorell M, Mardones L.The role of vitamin C in cancer prevention and therapy: a literature review.Antioxidants (Basel). 2021;10(12):1894. doi:10.3390/antiox10121894National Cancer Institute.Intravenous vitamin C (PDQ®)–health professional version.Wong SK, Chin KY, Ima-Nirwana S. Vitamin C:A review on its role in the management of metabolic syndrome.Int J Med Sci. 2020;17(11):1625-1638. doi:10.7150/ijms.47103Johns Hopkins Medicine.Metabolic syndrome.Morelli MB, Gambardella J, Castellanos V, Trimarco V, Santulli G.Vitamin C and cardiovascular disease: an update.Antioxidants (Basel). 2020;9(12):1227. doi:10.3390/antiox9121227Moser MA, Chun OK.Vitamin C and heart health: a review based on findings from epidemiologic studies. Int J Mol Sci. 2016;17(8):1328. doi:10.3390/ijms17081328Du W, Zhang S, Yang J, Fan H.Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.Asia Pac J Clin Nutr. 2024;33(4):503-514. doi:10.6133/apjcn.202412_33(4).0005Brzezińska O, Styrzyński F, Makowska J, Walczak K.Role of vitamin C in prophylaxis and treatment of gout—a literature review.Nutrients. 2021;13(2):701. doi:10.3390%2Fnu13020701Li N, Zhao G, Wu W, et al.The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: A randomized clinical trial.JAMA Netw Open. 2020;3(11):e2023644. Published 2020 Nov 2. doi:10.1001/jamanetworkopen.2020.23644American Academy of Ophthalmology.Vitamins for AMD,Lim JC, Caballero Arredondo M, Braakhuis AJ, Donaldson PJ.Vitamin C and the lens: new insights into delaying the onset of cataract.Nutrients. 2020;12(10):3142. doi:10.3390/nu12103142Carr AC, Rowe S.Factors affecting vitamin C status and prevalence of deficiency: a global health perspective.Nutrients. 2020;12(7):1963. doi:10.3390/nu12071963Aversa R, Petrescu RVV, Apicella A, Petrescu FIT.We are addicted to vitamins C and E-a review.Am. J. Eng. Appl. Sci. 2016;9(4):1003-1018. doi:10.3844/ajeassp.2016.1003.1018Lentjes MAH.The balance between food and dietary supplements in the general population.Proc Nutr Soc. 2019;78(1):97-109. doi:10.1017/S0029665118002525MedlinePlus.Vitamin C.My Food Data.Top 10 foods highest in vitamin C.Food and Drug Administration.Current Good Manufacturing Practices (CGMPs) for food and dietary supplements.Godoy HT, Amaya-Farfan J, Rodriguez-Amaya DB.Degradation of vitamins. Chemical changes during processing and storage of foods. 2021:329-383. doi:10.1016/b978-0-12-817380-0.00008-7Vargason AM, Anselmo AC, Mitragotri S.The evolution of commercial drug delivery technologies.Nat Biomed Eng. 2021;5(9):951-967. doi:10.1038/s41551-021-00698-Ghanwat G, Patil AJ, Patil J, Kshirsagar M, Sontakke A, Ayachit RK.Effect of Vitamin C supplementation on blood lead level, oxidative stress and antioxidant status of battery manufacturing workers of Western Maharashtra, India.J Clin Diagn Res. 2016;10(4):BC08-BC11. doi:10.7860/JCDR/2016/15968.7528

Office of Dietary Supplements.Vitamin C - fact sheet for health professionals.

Office of Dietary Supplements.Vitamin C - consumer.

Cerullo G, Negro M, Parimbelli M, et al.The long history of vitamin C: from prevention of the common cold to potential aid in the treatment of COVID-19.Front Immunol. 2020;11:574029. doi:10.3389/fimmu.2020.574029

Huijskens MJ, Walczak M, Koller N, et al.Technical advance: ascorbic acid induces the development of double-positive T cells from human hematopoietic stem cells in the absence of stromal cells.J Leukoc Biol. 2014;96(6):1165-1175. doi:10.1189/jlb.1TA0214-121RR

Carr AC, Maggini S.Vitamin C and immune function.Nutrients. 2017;9(11):1211. doi:10.3390/nu9111211

Pullar J, Carr A, Vissers M.The roles of vitamin C in skin health.Nutrients. 2017;9(8):866. doi:10.3390/nu9080866

Crook J, Horgas A, Yoon SJ, Grundmann O, Johnson-Mallard V.Insufficient vitamin C levels among adults in the United States: Results from the NHANES Surveys, 2003-2006. Nutrients. 2021;13(11):3910. Published 2021 Oct 30. doi:10.3390/nu13113910

Villagran M, Ferreira J, Martorell M, Mardones L.The role of vitamin C in cancer prevention and therapy: a literature review.Antioxidants (Basel). 2021;10(12):1894. doi:10.3390/antiox10121894

National Cancer Institute.Intravenous vitamin C (PDQ®)–health professional version.

Wong SK, Chin KY, Ima-Nirwana S. Vitamin C:A review on its role in the management of metabolic syndrome.Int J Med Sci. 2020;17(11):1625-1638. doi:10.7150/ijms.47103

Johns Hopkins Medicine.Metabolic syndrome.

Morelli MB, Gambardella J, Castellanos V, Trimarco V, Santulli G.Vitamin C and cardiovascular disease: an update.Antioxidants (Basel). 2020;9(12):1227. doi:10.3390/antiox9121227

Moser MA, Chun OK.Vitamin C and heart health: a review based on findings from epidemiologic studies. Int J Mol Sci. 2016;17(8):1328. doi:10.3390/ijms17081328

Du W, Zhang S, Yang J, Fan H.Effect of vitamin C and hawthorn beverage formula on blood pressure and oxidative stress in heat-exposed workers: a cluster-randomized controlled trial.Asia Pac J Clin Nutr. 2024;33(4):503-514. doi:10.6133/apjcn.202412_33(4).0005

Brzezińska O, Styrzyński F, Makowska J, Walczak K.Role of vitamin C in prophylaxis and treatment of gout—a literature review.Nutrients. 2021;13(2):701. doi:10.3390%2Fnu13020701

Li N, Zhao G, Wu W, et al.The efficacy and safety of vitamin C for iron supplementation in adult patients with iron deficiency anemia: A randomized clinical trial.JAMA Netw Open. 2020;3(11):e2023644. Published 2020 Nov 2. doi:10.1001/jamanetworkopen.2020.23644

American Academy of Ophthalmology.Vitamins for AMD,

Lim JC, Caballero Arredondo M, Braakhuis AJ, Donaldson PJ.Vitamin C and the lens: new insights into delaying the onset of cataract.Nutrients. 2020;12(10):3142. doi:10.3390/nu12103142

Carr AC, Rowe S.Factors affecting vitamin C status and prevalence of deficiency: a global health perspective.Nutrients. 2020;12(7):1963. doi:10.3390/nu12071963

Aversa R, Petrescu RVV, Apicella A, Petrescu FIT.We are addicted to vitamins C and E-a review.Am. J. Eng. Appl. Sci. 2016;9(4):1003-1018. doi:10.3844/ajeassp.2016.1003.1018

Lentjes MAH.The balance between food and dietary supplements in the general population.Proc Nutr Soc. 2019;78(1):97-109. doi:10.1017/S0029665118002525

MedlinePlus.Vitamin C.

My Food Data.Top 10 foods highest in vitamin C.

Food and Drug Administration.Current Good Manufacturing Practices (CGMPs) for food and dietary supplements.

Godoy HT, Amaya-Farfan J, Rodriguez-Amaya DB.Degradation of vitamins. Chemical changes during processing and storage of foods. 2021:329-383. doi:10.1016/b978-0-12-817380-0.00008-7

Vargason AM, Anselmo AC, Mitragotri S.The evolution of commercial drug delivery technologies.Nat Biomed Eng. 2021;5(9):951-967. doi:10.1038/s41551-021-00698-

Ghanwat G, Patil AJ, Patil J, Kshirsagar M, Sontakke A, Ayachit RK.Effect of Vitamin C supplementation on blood lead level, oxidative stress and antioxidant status of battery manufacturing workers of Western Maharashtra, India.J Clin Diagn Res. 2016;10(4):BC08-BC11. doi:10.7860/JCDR/2016/15968.7528

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