Table of ContentsView AllTable of ContentsTreatmentsLength of TreatmentManaging Post-Thrombotic SyndromeHabits for Better CirculationComplementary
Table of ContentsView All
View All
Table of Contents
Treatments
Length of Treatment
Managing Post-Thrombotic Syndrome
Habits for Better Circulation
Complementary
Deep vein thrombosis(DVT) occurs when ablood clotforms in a deep vein, typically in the legs. Treating a DVT is crucial, as the clot can break loose from the affected vein, move through the bloodstream to the heart, and lodge itself within the lung’s main artery. This complication—what’s known aspulmonary embolism—can be fatal.
Blood-thinning medications calledanticoagulantsare essential for preventing pulmonary embolism after a DVT diagnosis. Other therapies like taking a clot-dissolving drug or placing a device near the heart to trap blood clots are considered in select clinical scenarios.
This article will explore the treatment of DVT and the management ofpost-thrombotic syndrome, a common DVT complication. Supportive remedies, like early ambulation andcompression stockings, will also be briefly reviewed.
Oliver Helbig / Getty Images
Important NoteHome or natural therapies like compression stockings are intended to be supportive and not therapeutic when it comes to DVT care. Medical treatment is vital to treating DVT and helping prevent pulmonary embolism, among other complications.
Important Note
Home or natural therapies like compression stockings are intended to be supportive and not therapeutic when it comes to DVT care. Medical treatment is vital to treating DVT and helping prevent pulmonary embolism, among other complications.
Treatments for Blood Clots in Legs
The cornerstone of treatment for deep vein thrombosis is taking an anticoagulant, also known as a blood thinner.
In select cases, other options may be considered, namely administering a powerful “clot-busting” drug (thrombolytic) or placing a filter near the heart to help trap clots traveling up from the legs.
Anticoagulants
Anticoagulants do not dissolve blood clots. Instead, they impair clot formation, giving the body’s “fibrinolytic system” time to lyse or degrade the clot.
The primary reason for taking an anticoagulant for a DVT is to prevent pulmonary embolism.Other goals include:
Anticoagulant agents to treat DVT include:
Selecting an anticoagulant regimen depends on several factors, including:
12 Commonly Prescribed Blood Thinners
Thrombolytics
Thrombolytics can be administered in two ways:
The drawback with thrombolytics is that they carry a risk of significant bleeding. They are reserved for high-risk cases, like extensive proximal (upper leg vein) blood clots or people withphlegmasia cerulea dolens(PCD).
PCD is a severe complication of DVT associated with extreme leg swelling, pain, and a bluish-purplish skin discoloration. It results from a massive blood clot that blocks blood flow through the affected leg.
IVC Filter
An IVC filter is a small wire device placed in theinferior vena cavato trap traveling blood clots and prevent pulmonary embolism.
What Is the Inferior Vena Cava?The inferior vena cava is a large abdominal vein that returns oxygen-poor blood from the lower half of the body to the heart.
What Is the Inferior Vena Cava?
The inferior vena cava is a large abdominal vein that returns oxygen-poor blood from the lower half of the body to the heart.
IVC filters do not prevent the formation of new clots and are not nearly as effective as anticoagulation in preventing pulmonary embolism. That said, sometimes they are the next best and only option.
An interventionalradiologistusually performs this procedure as an outpatient. This minimally invasive procedure involves guiding a catheter with a collapsed filter mounted on it through a cut in the groin or neck.
Once in place, the filter opens (imagine an umbrella), and the catheter is withdrawn. The filter anchors itself to the wall of the IVC to trap blood clots before they reach the heart while still allowing blood to flow freely.
Indications for IVC filter placement include:
What Is Deep Vein Thrombosis?
How Long to Keep Treating a Blood Clot in Legs
Anticoagulation is started immediately after a DVT is detected unless there is a clear contraindication, such as active or high risk of bleeding.
The specific duration of anticoagulation depends on a person’s risk of developing another blood clot. That said, anticoagulation is generally given for a minimum of three months. In some cases, it’s continued for six to 12 months or even indefinitely.
Providers use various tools to help predict blood clot recurrence risk. A person’s risk of major bleeding is also factored into the decision regarding treatment duration.
Post-thrombotic syndrome is the most frequent complication of DVT, manifesting in 20% to 50% of people within two years of being diagnosed.
Typical symptoms include:
The key to preventing post-thrombotic syndrome is to take your anticoagulant therapy precisely as instructed and to follow closely with your provider.
If post-thrombotic syndrome does develop, management strategies include the following:
Sometimes, a venous-return assist device—a compression pump worn on the calf to optimize blood flow—may be considered.
Various surgical procedures likestenting(placing a tube in the vein to improve blood flow) can also be performed on people with severe symptoms.
Habits to Promote Better Circulation
Early walking after being anticoagulated for a blood clot in the leg is strongly encouraged to prevent post-thrombotic syndrome, increase quality of life, and decrease leg pain and swelling.
Elastic graduated compression stockings are also sometimes worn for up to two years after being diagnosed with a DVT. However, keep in mind the research supporting their benefit in preventing post-thrombotic syndrome is mixed.
Besides preventing post-thrombotic syndrome, early ambulation and wearing compression stockings during situations that pose a high risk for developing leg blood clots (e.g., after surgery and during air travel, respectively) can also help prevent DVTs.
Other lifestyle habits to helpprevent DVTsinclude:
Certain medications are also linked to a higher DVT risk—for example,birth control pillsandhormone replacement therapy(estrogen or estrogen and progesterone).
Speak With Your Healthcare ProviderIf you have a personal or family history of DVTs or clotting disorder, be proactive and speak with your prescribing healthcare provider before taking any new medication to ensure it is safe and appropriate for your care.
Speak With Your Healthcare Provider
If you have a personal or family history of DVTs or clotting disorder, be proactive and speak with your prescribing healthcare provider before taking any new medication to ensure it is safe and appropriate for your care.
An Overview of Birth Control and the Risk for Blood Clots
Complementary Role of Food in Dissolving Leg Blood Clots
Certain herbs and supplements—for example,turmeric,ginseng, andvitamin E— are known to have blood-thinning properties, although their ability to help prevent blood clots remains unknown.
Moreover, these and other herbs or supplements can interact with medications, including blood thinners, so they should only ever be taken under the guidance of a healthcare provider.
Ultimately, natural remedies should never substitute medical care for a blood clot in the leg.
Summary
A deep vein thrombosis (DVT) is a blood clot found in a vein, usually within the leg. The primary concern with a DVT is a potentially life-threatening complication called a pulmonary embolism (when the blood clot travels through the bloodstream to a major lung artery).
Taking an anticoagulant (blood-thinner) is the mainstay treatment for DVT. Anticoagulants can help prevent pulmonary embolism, new clots from forming, and other long-term DVT complications like post-thrombotic syndrome.
In select cases (e.g., a person cannot take an anticoagulant due to active bleeding), a small device called an IVC filter is placed near the heart to prevent blood clots from traveling to the lungs. Less commonly, a clot-busting drug called a thrombolytic may be administered.
Supportive or home remedies play a complementary role in treating DVTs, namely early ambulation after starting anticoagulation. Lifestyle habits like wearing compression stockings during extended travel, maintaining a healthy weight, smoking cessation, and staying active can also help prevent DVTs.
A healthcare provider must evaluate all suspected blood clots. If a DVT in the leg is diagnosed, anticoagulation is vital to preventing it from traveling to the heart and potentially causing death.
14 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Watson L, Broderick C, Armon MP.Thrombolysis for acute deep vein thrombosis.Cochrane Database Syst Rev. 2016;11(11):CD002783. doi:10.1002/14651858.CD002783.pub4Chiasakul T, Bauer KA.Thrombolytic therapy in acute venous thromboembolism.Hematology Am Soc Hematol Educ Program. 2020;2020(1):612-618. doi:10.1182/hematology.2020000148Stone J, Hangge P, Albadawi H, et al.Deep vein thrombosis: pathogenesis, diagnosis, and medical management.Cardiovasc Diagn Ther. 2017;7(Suppl 3):S276-S284. doi:10.21037/cdt.2017.09.01Lip GYH.Overview of the treatment of proximal and distal lower extremity deep vein thrombosis. In: UpToDate, Mandel J, Douketis JD (Eds).Chaochankit W, Akaraborworn O.Phlegmasia cerulea dolens with compartment syndrome.Ann Vasc Dis. 2018;11(3):355-357. doi:10.3400/avd.cr.18-00030DeYoung E, Minocha J.Inferior vena cava filters: guidelines, best practice, and expanding indications.Semin Intervent Radiol. 2016;33(2):65-70. doi:10.1055/s-0036-1581088Malhotra A, Kishore S, Trost D, Madoff DC, Winokur RS.Inferior vena cava filters and prevention of recurrent pulmonary embolism.Semin Intervent Radiol. 2018;35(2):105-107. doi:10.1055/s-0038-1642038Kahn SR, Galanaud JP, Vedantham S, Ginsberg JS.Guidance for the prevention and treatment of the post-thrombotic syndrome.J Thromb Thrombolysis. 2016;41(1):144-53. doi:10.1007/s11239-015-1312-5Makedonov I, Kahn SR, Galanaud JP.Prevention and management of the post-thrombotic syndrome.J Clin Med. 2020;9(4):923. doi:10.3390/jcm9040923Rook B, van Rijn MJE, Jansma EP, van Montfrans C.Effect of exercise after a deep venous thrombosis: a systematic review.J Eur Acad Dermatol Venereol. 2024;38(2):289-301. doi:10.1111/jdv.19523Clarke MJ, Broderick C, Hopewell S, Juszczak E, Eisinga A.Compression stockings for preventing deep vein thrombosis in airline passengers.Cochrane Database Syst Rev. 2021;4(4):CD004002. doi:10.1002/14651858.CD004002.pub4Yuan S, Bruzelius M, Damrauer SM, et al.Anti-inflammatory diet and venous thromboembolism: two prospective cohort studies.Nutr Metab Cardiovasc Dis. 2021;31(10):2831-2838. doi:10.1016/j.numecd.2021.06.021Nicholson M, Chan N, Bhagirath V, Ginsberg J.Prevention of venous thromboembolism in 2020 and beyond.J Clin Med. 2020;9(8):2467. doi:10.3390/jcm9082467Keihanian F, Saeidinia A, Bagheri RK, Johnston TP, Sahebkar A.Curcumin, hemostasis, thrombosis, and coagulation.J Cell Physiol. 2018;233(6):4497-4511. doi:10.1002/jcp.26249
14 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Watson L, Broderick C, Armon MP.Thrombolysis for acute deep vein thrombosis.Cochrane Database Syst Rev. 2016;11(11):CD002783. doi:10.1002/14651858.CD002783.pub4Chiasakul T, Bauer KA.Thrombolytic therapy in acute venous thromboembolism.Hematology Am Soc Hematol Educ Program. 2020;2020(1):612-618. doi:10.1182/hematology.2020000148Stone J, Hangge P, Albadawi H, et al.Deep vein thrombosis: pathogenesis, diagnosis, and medical management.Cardiovasc Diagn Ther. 2017;7(Suppl 3):S276-S284. doi:10.21037/cdt.2017.09.01Lip GYH.Overview of the treatment of proximal and distal lower extremity deep vein thrombosis. In: UpToDate, Mandel J, Douketis JD (Eds).Chaochankit W, Akaraborworn O.Phlegmasia cerulea dolens with compartment syndrome.Ann Vasc Dis. 2018;11(3):355-357. doi:10.3400/avd.cr.18-00030DeYoung E, Minocha J.Inferior vena cava filters: guidelines, best practice, and expanding indications.Semin Intervent Radiol. 2016;33(2):65-70. doi:10.1055/s-0036-1581088Malhotra A, Kishore S, Trost D, Madoff DC, Winokur RS.Inferior vena cava filters and prevention of recurrent pulmonary embolism.Semin Intervent Radiol. 2018;35(2):105-107. doi:10.1055/s-0038-1642038Kahn SR, Galanaud JP, Vedantham S, Ginsberg JS.Guidance for the prevention and treatment of the post-thrombotic syndrome.J Thromb Thrombolysis. 2016;41(1):144-53. doi:10.1007/s11239-015-1312-5Makedonov I, Kahn SR, Galanaud JP.Prevention and management of the post-thrombotic syndrome.J Clin Med. 2020;9(4):923. doi:10.3390/jcm9040923Rook B, van Rijn MJE, Jansma EP, van Montfrans C.Effect of exercise after a deep venous thrombosis: a systematic review.J Eur Acad Dermatol Venereol. 2024;38(2):289-301. doi:10.1111/jdv.19523Clarke MJ, Broderick C, Hopewell S, Juszczak E, Eisinga A.Compression stockings for preventing deep vein thrombosis in airline passengers.Cochrane Database Syst Rev. 2021;4(4):CD004002. doi:10.1002/14651858.CD004002.pub4Yuan S, Bruzelius M, Damrauer SM, et al.Anti-inflammatory diet and venous thromboembolism: two prospective cohort studies.Nutr Metab Cardiovasc Dis. 2021;31(10):2831-2838. doi:10.1016/j.numecd.2021.06.021Nicholson M, Chan N, Bhagirath V, Ginsberg J.Prevention of venous thromboembolism in 2020 and beyond.J Clin Med. 2020;9(8):2467. doi:10.3390/jcm9082467Keihanian F, Saeidinia A, Bagheri RK, Johnston TP, Sahebkar A.Curcumin, hemostasis, thrombosis, and coagulation.J Cell Physiol. 2018;233(6):4497-4511. doi:10.1002/jcp.26249
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Watson L, Broderick C, Armon MP.Thrombolysis for acute deep vein thrombosis.Cochrane Database Syst Rev. 2016;11(11):CD002783. doi:10.1002/14651858.CD002783.pub4Chiasakul T, Bauer KA.Thrombolytic therapy in acute venous thromboembolism.Hematology Am Soc Hematol Educ Program. 2020;2020(1):612-618. doi:10.1182/hematology.2020000148Stone J, Hangge P, Albadawi H, et al.Deep vein thrombosis: pathogenesis, diagnosis, and medical management.Cardiovasc Diagn Ther. 2017;7(Suppl 3):S276-S284. doi:10.21037/cdt.2017.09.01Lip GYH.Overview of the treatment of proximal and distal lower extremity deep vein thrombosis. In: UpToDate, Mandel J, Douketis JD (Eds).Chaochankit W, Akaraborworn O.Phlegmasia cerulea dolens with compartment syndrome.Ann Vasc Dis. 2018;11(3):355-357. doi:10.3400/avd.cr.18-00030DeYoung E, Minocha J.Inferior vena cava filters: guidelines, best practice, and expanding indications.Semin Intervent Radiol. 2016;33(2):65-70. doi:10.1055/s-0036-1581088Malhotra A, Kishore S, Trost D, Madoff DC, Winokur RS.Inferior vena cava filters and prevention of recurrent pulmonary embolism.Semin Intervent Radiol. 2018;35(2):105-107. doi:10.1055/s-0038-1642038Kahn SR, Galanaud JP, Vedantham S, Ginsberg JS.Guidance for the prevention and treatment of the post-thrombotic syndrome.J Thromb Thrombolysis. 2016;41(1):144-53. doi:10.1007/s11239-015-1312-5Makedonov I, Kahn SR, Galanaud JP.Prevention and management of the post-thrombotic syndrome.J Clin Med. 2020;9(4):923. doi:10.3390/jcm9040923Rook B, van Rijn MJE, Jansma EP, van Montfrans C.Effect of exercise after a deep venous thrombosis: a systematic review.J Eur Acad Dermatol Venereol. 2024;38(2):289-301. doi:10.1111/jdv.19523Clarke MJ, Broderick C, Hopewell S, Juszczak E, Eisinga A.Compression stockings for preventing deep vein thrombosis in airline passengers.Cochrane Database Syst Rev. 2021;4(4):CD004002. doi:10.1002/14651858.CD004002.pub4Yuan S, Bruzelius M, Damrauer SM, et al.Anti-inflammatory diet and venous thromboembolism: two prospective cohort studies.Nutr Metab Cardiovasc Dis. 2021;31(10):2831-2838. doi:10.1016/j.numecd.2021.06.021Nicholson M, Chan N, Bhagirath V, Ginsberg J.Prevention of venous thromboembolism in 2020 and beyond.J Clin Med. 2020;9(8):2467. doi:10.3390/jcm9082467Keihanian F, Saeidinia A, Bagheri RK, Johnston TP, Sahebkar A.Curcumin, hemostasis, thrombosis, and coagulation.J Cell Physiol. 2018;233(6):4497-4511. doi:10.1002/jcp.26249
Watson L, Broderick C, Armon MP.Thrombolysis for acute deep vein thrombosis.Cochrane Database Syst Rev. 2016;11(11):CD002783. doi:10.1002/14651858.CD002783.pub4
Chiasakul T, Bauer KA.Thrombolytic therapy in acute venous thromboembolism.Hematology Am Soc Hematol Educ Program. 2020;2020(1):612-618. doi:10.1182/hematology.2020000148
Stone J, Hangge P, Albadawi H, et al.Deep vein thrombosis: pathogenesis, diagnosis, and medical management.Cardiovasc Diagn Ther. 2017;7(Suppl 3):S276-S284. doi:10.21037/cdt.2017.09.01
Lip GYH.Overview of the treatment of proximal and distal lower extremity deep vein thrombosis. In: UpToDate, Mandel J, Douketis JD (Eds).
Chaochankit W, Akaraborworn O.Phlegmasia cerulea dolens with compartment syndrome.Ann Vasc Dis. 2018;11(3):355-357. doi:10.3400/avd.cr.18-00030
DeYoung E, Minocha J.Inferior vena cava filters: guidelines, best practice, and expanding indications.Semin Intervent Radiol. 2016;33(2):65-70. doi:10.1055/s-0036-1581088
Malhotra A, Kishore S, Trost D, Madoff DC, Winokur RS.Inferior vena cava filters and prevention of recurrent pulmonary embolism.Semin Intervent Radiol. 2018;35(2):105-107. doi:10.1055/s-0038-1642038
Kahn SR, Galanaud JP, Vedantham S, Ginsberg JS.Guidance for the prevention and treatment of the post-thrombotic syndrome.J Thromb Thrombolysis. 2016;41(1):144-53. doi:10.1007/s11239-015-1312-5
Makedonov I, Kahn SR, Galanaud JP.Prevention and management of the post-thrombotic syndrome.J Clin Med. 2020;9(4):923. doi:10.3390/jcm9040923
Rook B, van Rijn MJE, Jansma EP, van Montfrans C.Effect of exercise after a deep venous thrombosis: a systematic review.J Eur Acad Dermatol Venereol. 2024;38(2):289-301. doi:10.1111/jdv.19523
Clarke MJ, Broderick C, Hopewell S, Juszczak E, Eisinga A.Compression stockings for preventing deep vein thrombosis in airline passengers.Cochrane Database Syst Rev. 2021;4(4):CD004002. doi:10.1002/14651858.CD004002.pub4
Yuan S, Bruzelius M, Damrauer SM, et al.Anti-inflammatory diet and venous thromboembolism: two prospective cohort studies.Nutr Metab Cardiovasc Dis. 2021;31(10):2831-2838. doi:10.1016/j.numecd.2021.06.021
Nicholson M, Chan N, Bhagirath V, Ginsberg J.Prevention of venous thromboembolism in 2020 and beyond.J Clin Med. 2020;9(8):2467. doi:10.3390/jcm9082467
Keihanian F, Saeidinia A, Bagheri RK, Johnston TP, Sahebkar A.Curcumin, hemostasis, thrombosis, and coagulation.J Cell Physiol. 2018;233(6):4497-4511. doi:10.1002/jcp.26249
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