Premenstrual syndrome (PMS) affects most menstruating people to some extent at some time during their reproductive years. While most people think of PMS as only causing mood changes, symptoms can range from mental to physical. Common symptoms of PMS include mood changes, depression, irritable behavior, food cravings, bloating,breast tenderness, fatigue, cramping, acne, and headaches.
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Reducing the effects of PMS depends on what kind of symptoms you have. If your symptoms are purely physical—bloating, breast tenderness, fatigue—medications that address the mental health symptoms of PMS are unlikely to help. If you experience both physical and mental symptoms, you might want to target and treat each symptom separately or try a treatment that can help a variety of symptoms.
Treating Mood Changes
Some people have a more severe form of PMS known aspremenstrual dysphoric disorder(PMDD). PMDD can cause severe changes in mood that can make it difficult to function normally in the days preceding menstruation. Physical symptoms, like the ones experienced in PMS, may accompany mood changes
If you have severe mood swings, your doctor might prescribe you Sarafem, an FDA-approved medication for PMDD. Sarafem is a renamed and chemically equivalent version of Prozac, a selective serotonin reuptake inhibitor (SSRI). These are not the only SSRIs that can help treat depression, anxiety, and mood changes related to PMDD or PMS. Your doctor may prescribe you a different SSRI.

PMDD vs. PMS: When Physical and Mental Symptoms Aren’t Normal
Treating Multiple Symptoms of PMS
Oral contraceptives are known to be effective in treating PMS and PMDD.
Regular exercise can also decrease premenstrual syndrome symptoms, plus, it is an excellent way to reduce stress and lower your risk of other conditions such as heart disease andcancer.
Dietary changes that may help reduce the symptoms of PMS include following a low-fat vegetarian diet, or reducing your intake of sugar, dairy, red meat, alcohol, and caffeine—all known to be inflammatory foods. Instead, increase your consumption of complex carbohydrates, leafy green vegetables, fruits, and whole grains.
Supplements, Vitamins, and Over the Counter Medications
Over-the-counter treatments that may help include ibuprofen, naproxen, and other drugs specifically made for relieving premenstrual symptoms. Aspirin is not the best choice because of its potential to increase the length and severity of menstrual bleeding.
2 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Kwan I, Onwude JL.Premenstrual syndrome.BMJ Clin Evid. 2015;2015:0806.Kiryanova V, Mcallister BB, Dyck RH.Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature.Dev Neurosci. 2013;35(6):437-9. doi:10.1159/000355709Additional ReadingEase PMS Symptoms. Healthywomen.gov.
2 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Kwan I, Onwude JL.Premenstrual syndrome.BMJ Clin Evid. 2015;2015:0806.Kiryanova V, Mcallister BB, Dyck RH.Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature.Dev Neurosci. 2013;35(6):437-9. doi:10.1159/000355709Additional ReadingEase PMS Symptoms. Healthywomen.gov.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Kwan I, Onwude JL.Premenstrual syndrome.BMJ Clin Evid. 2015;2015:0806.Kiryanova V, Mcallister BB, Dyck RH.Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature.Dev Neurosci. 2013;35(6):437-9. doi:10.1159/000355709
Kwan I, Onwude JL.Premenstrual syndrome.BMJ Clin Evid. 2015;2015:0806.
Kiryanova V, Mcallister BB, Dyck RH.Long-term outcomes of developmental exposure to fluoxetine: a review of the animal literature.Dev Neurosci. 2013;35(6):437-9. doi:10.1159/000355709
Ease PMS Symptoms. Healthywomen.gov.
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