Table of ContentsView AllTable of ContentsScheduleBenefitsHesitancyIngredientsAdult VaccineOngoing ScreeningFrequently Asked Questions
Table of ContentsView All
View All
Table of Contents
Schedule
Benefits
Hesitancy
Ingredients
Adult Vaccine
Ongoing Screening
Frequently Asked Questions
HPV infections usually go undetected because they don’t always present symptoms and tend to go away on their own. Some types of HPV can causegenital warts, while others can become more serious and lead to cancer of thecervix,vulva,vagina,penis, anus, or back of the throat.
BURGER / PHANIE / Getty Images
A Note on Gender and Sex TerminologyVerywell Health acknowledges thatsex and gender are related concepts, but they are not the same. To reflect our sources accurately, this article uses terms like “female,” “male,” “woman,” and “man” as the sources use them.
A Note on Gender and Sex Terminology
Verywell Health acknowledges thatsex and gender are related concepts, but they are not the same. To reflect our sources accurately, this article uses terms like “female,” “male,” “woman,” and “man” as the sources use them.
HPV Vaccine Schedule
There are three different HPV vaccine types currently licensed in the United States:
Currently,Gardasil 9 is the only one available for use.
Understanding Human Papillomavirus (HPV) Infection Symptoms
When to Get Vaccinated
According to the CDC, the ideal age range to receive the HPV vaccine is between 11 and 12 years old. However, adolescents as young as 9 years old and adults up to age 45 may be candidates for the vaccine.
A person’s age and immune status may determine how many doses of the vaccine they receive.
Age Range for Two Doses
A two-dose regimen is recommended for people ages 9 to 14. The first dose must be initiated before a person turns 15 to fall under the two-dose schedule.
Research shows that children in the 9-14 age range who receive two doses of the vaccine at least six months apart have equal or greater protection than people over the age of 15 who receive three doses.
Two Dose ScheduleDose 1: Administered sometime between the ages of 9 to 14Dose 2: Administered six to 12 months after the first dose
Two Dose Schedule
Dose 1: Administered sometime between the ages of 9 to 14Dose 2: Administered six to 12 months after the first dose
Age Range for Three Doses
People who get the first dose of the HPV vaccine after their 15th birthday require three doses. The three dose regimen is recommended for people ages 15 to 26 and for individuals ages 9 to 14 who have a compromisedimmune system.
Three Dose ScheduleDose 1: Administered sometime between the ages of 15 to 26Dose 2: Administered one to two months after the first doseDose 3: Administered six months after the first dose
Three Dose Schedule
Dose 1: Administered sometime between the ages of 15 to 26Dose 2: Administered one to two months after the first doseDose 3: Administered six months after the first dose
What the HPV Vaccine Does If You’re Already Infected
Benefits of HPV Vaccine Protection
HPV can lead tocervical cancerand other cancers of the vagina, vulva, penis, anus, and throat.Vaccination is one of the best tools available to help protect against these cancers.
The HPV vaccine has been available since 2006, and ongoing monitoring has shown the vaccine to be safe and effective.
HPV Vaccination in BoysHistorically, HPV vaccination efforts have been focused on young women and girls since their risk for developing HPV-related cancers is 10 times higher than males. Men relied on herd immunity from women being vaccinated against HPV as their primary method of prevention. Those efforts have shifted as HPV vaccines among both men and women continue to provide long-lasting protection in both sexes.As of 2011, the CDC recommends administration of theHPV vaccine to young men and boysaccording to a similar schedule as that for women.
HPV Vaccination in Boys
Historically, HPV vaccination efforts have been focused on young women and girls since their risk for developing HPV-related cancers is 10 times higher than males. Men relied on herd immunity from women being vaccinated against HPV as their primary method of prevention. Those efforts have shifted as HPV vaccines among both men and women continue to provide long-lasting protection in both sexes.As of 2011, the CDC recommends administration of theHPV vaccine to young men and boysaccording to a similar schedule as that for women.
Side Effects
Most vaccines do come with side effects, and the HPV vaccine is no exception.
However, side effects of the Gardasil-9 shot are typically mild and the incidence of serious adverse reactions is uncommon. In fact, a study of nearly 1 million girls who had received their HPV vaccine found no serious adverse effects such as neurological or autoimmune responses.
Possible Side EffectsPossible side effects of the HPV vaccine include:Pain, redness, or swelling at the injection siteFeverDizziness or faintingNauseaHeadacheFatigueMuscle or joint painThese side effects usually resolve a day or two after the injection.
Possible Side Effects
Possible side effects of the HPV vaccine include:Pain, redness, or swelling at the injection siteFeverDizziness or faintingNauseaHeadacheFatigueMuscle or joint painThese side effects usually resolve a day or two after the injection.
Possible side effects of the HPV vaccine include:
These side effects usually resolve a day or two after the injection.
Parent Hesitancy
Parental education and engagement with the HPV vaccine for their children is crucial, yet knowledge of HPV and its relationship to cancer isn’t widely known.
A separate 2020 survey that evaluated parents' intentions to start and complete the HPV vaccination series found that parents of 58% of unvaccinated adolescents in the U.S. had no plans to initiate the series.
A total of 22.8% of respondents listed safety concerns as the most common reason why they did not intend to initiate the vaccine series. Of the survey respondents who were not planning to complete the series, 22.2% noted the lack of receiving a healthcare provider recommendation for subsequent doses.
Talking about your child’s sexual health can be uncomfortable, but having the discussion with their healthcare provider could determine the possibility of a cancer diagnosis later in your child’s life.
HPV Vaccine Ingredients
The ingredients in Gardasil 9 include:
Is There an HPV Vaccine for Adults?
TheHPV vaccine is not recommended for people over the age of 26. This is because the vaccine is more likely to benefit younger people, before they have already been exposed to HPV.
However, adults between the ages of 27 and 45 can talk to their healthcare provider to learn if they could benefit from receiving the vaccine.
If it’s determined that an adult over the age of 26 could benefit from the HPV vaccine, they should follow the three-dose regimen.
Ongoing Screening for HPV
The provider uses a tool called a speculum, which is placed in the vagina to visualize the cervix. Your provider will use an instrument to collect cells from the cervix. The pap smear looks to see if the collected cells are normal, and HPV testing specifically looks to see if HPV is present in the sample.
Regular inspection for genital warts is another way to screen for HPV. If you think you may have genital warts, talk to your healthcare provider about treatment options.
Summary
Initiating the HPV vaccine series during adolescence is the most effective way to prevent HPV-related cancers later in life. The CDC recommends that young people receive the two-dose vaccine at age 11 or 12, though anytime between the ages of 9 to 14 is acceptable.
If a person hasn’t been vaccinated before they turn 15, it’s recommended that they receive the three-dose vaccine series sometime between the ages of 15 and 26. People older than 26 can still receive the vaccine if their healthcare provider determines it is appropriate for them.
Ongoing monitoring over time has shown that HPV vaccine is safe, effective, and unlikely to cause side effects.
A Word From Verywell
The HPV vaccine is an effective tool to help prevent HPV-related cancers. Getting your child vaccinated during adolescence is the best way to protect them from the risks of HPV before they are even exposed. Talk to your healthcare provider about the benefits of HPV vaccination.
Learn MoreWhat to Know About HPV Vaccines
The first round of Gardasil was recalled out of an abundance of caution after it was found that a select number of vials may have contained small glass particles.
The HPV vaccine protects against the types of HPV that cause cancer. It is possible to get other types of HPV after being vaccinated, but the risk for serious illness as a result of that infection is significantly reduced.
Yes, to ensure adequate protection against HPV, three doses of the HPV vaccine are necessary in people who begin the regimen after they turn 15.
The ideal timeframe for HPV vaccine administration is before a person becomes sexually active. By age 26, most people have been exposed to HPV and therefore do not benefit from the vaccine. Every person is different, so talk to your healthcare provider if you feel that you could benefit from the HPV vaccine.
12 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Centers for Disease Control and Prevention.Reasons to get vaccinated.NIH National Cancer Institute.Human papillomavirus (HPV) vaccines.Centers for Disease Control and Prevention. HPV vaccine recommendations.Cheng L, Wang Y, Du J.Human papillomavirus vaccines: an updated review.Vaccines. 2020;8(3):391. doi:10.3390/vaccines8030391Centers for Disease Control and Prevention.Recommendations on the use of the quadrivalent human papillomavirus vaccine in males - Advisory Committee on Immunization Practices (ACIP) 2011).MMWR Morb Mortal Week Rep.2011;60(5):1705-1708.Centers for Disease Control and Prevention.Hepatitis B vaccine safety.Suk R, Montealegre JR, Nemutlu GS, et al.Public knowledge of human papillomavirus and receipt of vaccination recommendations.JAMA Pediatr. 2019;173(11):1099-1102. doi:10.1001/jamapediatrics.2019.3105Sonawane K, Zhu Y, Montealegre JR, et al.Parental intent to initiate and complete the human papillomavirus vaccine series in the US: findings from a nationwide cross-sectional survey.Lancet Public Health. 2020;5(9):e484-e492. doi:10.1016/ S2468-2667(20)30139-0Merck.Gardasil 9: frequently asked questions.Centers for Disease Control and Prevention.Screening for cervical cancer.Centers for Disease Control and Prevention.Human papillomavirus (HPV) vaccine safety.Centers for Disease Control and Prevention.HPV vaccine safety and effectiveness.
12 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Centers for Disease Control and Prevention.Reasons to get vaccinated.NIH National Cancer Institute.Human papillomavirus (HPV) vaccines.Centers for Disease Control and Prevention. HPV vaccine recommendations.Cheng L, Wang Y, Du J.Human papillomavirus vaccines: an updated review.Vaccines. 2020;8(3):391. doi:10.3390/vaccines8030391Centers for Disease Control and Prevention.Recommendations on the use of the quadrivalent human papillomavirus vaccine in males - Advisory Committee on Immunization Practices (ACIP) 2011).MMWR Morb Mortal Week Rep.2011;60(5):1705-1708.Centers for Disease Control and Prevention.Hepatitis B vaccine safety.Suk R, Montealegre JR, Nemutlu GS, et al.Public knowledge of human papillomavirus and receipt of vaccination recommendations.JAMA Pediatr. 2019;173(11):1099-1102. doi:10.1001/jamapediatrics.2019.3105Sonawane K, Zhu Y, Montealegre JR, et al.Parental intent to initiate and complete the human papillomavirus vaccine series in the US: findings from a nationwide cross-sectional survey.Lancet Public Health. 2020;5(9):e484-e492. doi:10.1016/ S2468-2667(20)30139-0Merck.Gardasil 9: frequently asked questions.Centers for Disease Control and Prevention.Screening for cervical cancer.Centers for Disease Control and Prevention.Human papillomavirus (HPV) vaccine safety.Centers for Disease Control and Prevention.HPV vaccine safety and effectiveness.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Centers for Disease Control and Prevention.Reasons to get vaccinated.NIH National Cancer Institute.Human papillomavirus (HPV) vaccines.Centers for Disease Control and Prevention. HPV vaccine recommendations.Cheng L, Wang Y, Du J.Human papillomavirus vaccines: an updated review.Vaccines. 2020;8(3):391. doi:10.3390/vaccines8030391Centers for Disease Control and Prevention.Recommendations on the use of the quadrivalent human papillomavirus vaccine in males - Advisory Committee on Immunization Practices (ACIP) 2011).MMWR Morb Mortal Week Rep.2011;60(5):1705-1708.Centers for Disease Control and Prevention.Hepatitis B vaccine safety.Suk R, Montealegre JR, Nemutlu GS, et al.Public knowledge of human papillomavirus and receipt of vaccination recommendations.JAMA Pediatr. 2019;173(11):1099-1102. doi:10.1001/jamapediatrics.2019.3105Sonawane K, Zhu Y, Montealegre JR, et al.Parental intent to initiate and complete the human papillomavirus vaccine series in the US: findings from a nationwide cross-sectional survey.Lancet Public Health. 2020;5(9):e484-e492. doi:10.1016/ S2468-2667(20)30139-0Merck.Gardasil 9: frequently asked questions.Centers for Disease Control and Prevention.Screening for cervical cancer.Centers for Disease Control and Prevention.Human papillomavirus (HPV) vaccine safety.Centers for Disease Control and Prevention.HPV vaccine safety and effectiveness.
Centers for Disease Control and Prevention.Reasons to get vaccinated.
NIH National Cancer Institute.Human papillomavirus (HPV) vaccines.
Centers for Disease Control and Prevention. HPV vaccine recommendations.
Cheng L, Wang Y, Du J.Human papillomavirus vaccines: an updated review.Vaccines. 2020;8(3):391. doi:10.3390/vaccines8030391
Centers for Disease Control and Prevention.Recommendations on the use of the quadrivalent human papillomavirus vaccine in males - Advisory Committee on Immunization Practices (ACIP) 2011).MMWR Morb Mortal Week Rep.2011;60(5):1705-1708.
Centers for Disease Control and Prevention.Hepatitis B vaccine safety.
Suk R, Montealegre JR, Nemutlu GS, et al.Public knowledge of human papillomavirus and receipt of vaccination recommendations.JAMA Pediatr. 2019;173(11):1099-1102. doi:10.1001/jamapediatrics.2019.3105
Sonawane K, Zhu Y, Montealegre JR, et al.Parental intent to initiate and complete the human papillomavirus vaccine series in the US: findings from a nationwide cross-sectional survey.Lancet Public Health. 2020;5(9):e484-e492. doi:10.1016/ S2468-2667(20)30139-0
Merck.Gardasil 9: frequently asked questions.
Centers for Disease Control and Prevention.Screening for cervical cancer.
Centers for Disease Control and Prevention.Human papillomavirus (HPV) vaccine safety.
Centers for Disease Control and Prevention.HPV vaccine safety and effectiveness.
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