Table of ContentsView AllTable of ContentsTypesBenefitsMagnesium DeficiencyDosingRisks and Side Effects

Table of ContentsView All

View All

Table of Contents

Types

Benefits

Magnesium Deficiency

Dosing

Risks and Side Effects

One ofmagnesium’smost important jobs is making sure your bones are strong: 60% of the magnesium in your body is in your bones and teeth.Some studies have shown that not having enoughmagnesiumcan lead to inflammation, which can increase your risk of chronic diseases.

If you havearthritis, you’re probably already familiar with bone health and inflammation. This article will go over what research says about whether magnesium is helpful for people with arthritis.

Verywell / Laura Porter

Foods Rich in Magnesium

Types of Magnesium for Bone Health

There are many types of magnesium supplements, each with potential benefits. The following forms of magnesium may help reduce arthritic inflammation and pain.

A Word From VerywellMagnesium is a mineral that offers a wide variety of benefits, from relief of muscle cramps and headaches to improvement of mood and sleep.—STELLA BARD, MD, MEDICAL EXPERT BOARD

A Word From Verywell

Magnesium is a mineral that offers a wide variety of benefits, from relief of muscle cramps and headaches to improvement of mood and sleep.—STELLA BARD, MD, MEDICAL EXPERT BOARD

Magnesium is a mineral that offers a wide variety of benefits, from relief of muscle cramps and headaches to improvement of mood and sleep.

—STELLA BARD, MD, MEDICAL EXPERT BOARD

Stella Bard, MD

Magnesium Glycinate

Magnesium Citrate

Few studies have examined the effects of magnesium citrate on bone loss in people with osteoporosis. One study found that high doses of magnesium citrate (1,830 mg per day) can reduce the rate of bone loss in post-menopausal women with osteoporosis.

The results are promising, but more research is needed to determine if high doses of magnesium can be effective for preventing osteoporosis.

Magnesium Malate

Malic acid is known for its ability to reduce fatigue, which is a common symptom in many types of arthritis, especiallyfibromyalgia.

Magnesium Taurate

Which Type of Magnesium Is Good for Migraines?

Benefits of Magnesium for Arthritis

Maintains Joint Cartilage

The progressive breakdown of cartilage (connective tissue that protects joints and bones) is a distinguishing feature of osteoarthritis (OA).

Adequate magnesium levels prevent cartilage breakdown and prevent cytokine storms, which are inflammatory immune responses in which the body attacks its own cells and tissues, including cartilage.

Some researchers believe that magnesium may be so effective at protecting cartilage that the mineral could even be used as a clinical treatment for OA.

Strengthens Bones

Having enough magnesium in your body is necessary for bone density and bone development. This is important since people with certain types of arthritis have a higher risk of bone breaks (fractures).

Some research has shown that magnesium might help lower the risk of arthritis and bone fractures.For example, one study called the “Osteoarthritis Initiative” found that women who meet the recommended daily intake (RDI) for magnesium are approximately 27% less likely to experience fragility fractures in the future.

Reduces Inflammation

Arthritis causes inflammation in the body. Magnesium is known to reduce inflammation. Research has shown that the mineral may help people with inflammatory forms of arthritis.

Rheumatoid arthritis(RA) is an inflammatory and autoimmune disease. It affects the joints in the knees, wrists, and hands. People with RA often have chronic pain.

One study found that women who had higher amounts of magnesium in their diets were less likely to get RA. This could be because magnesium has anti-inflammatory properties.

Eases Muscle Pain

Magnesium supplements are commonly used in clinical practice for easing acute and chronic muscle pain. Specifically, magnesium is thought to relax muscles and nerves and reduce pain intensity.

Magnesium deficiency is closely linked to muscle pain, fatigue, sleep difficulties, and anxiety, all of which are common symptoms of fibromyalgia.A small body of research supports the use of magnesium for fibromyalgia pain.

One such study showed that people with fibromyalgia who took 300 mg of magnesium per day had reduced “tender points” after eight weeks. More research is needed to confirm these results.

Boosts Immune Function

Magnesium is crucial for a healthy immune system, as it improves your white blood cells' ability to find and fight germs. Additionally, low magnesium levels can trigger cytokine storms.

Cytokine storms are thought to play a key role in the development of various autoimmune diseases, including rheumatoid arthritis.

Low Magnesium Intake and Deficiency

Many Americans do not get enough magnesium in their diets. Studies have shown that about 65% of females between the ages of 19 and 30 and 48% of those between the ages of 30 and 50 consume less than the recommended dietary allowance of magnesium.

If you don’t get enough magnesium in your diet, you can become deficient. There are also other factors that can lead to magnesium deficiency, including:

Signs of magnesium deficiency include:

What Happens If You Don’t Get Enough Magnesium?

Dosage of Magnesium for Joint Health

The National Institutes of Health (NIH) sets recommendations for daily intake of different nutrients, including magnesium.

Magnesium Daily Intake RecommendationsAgeMaleFemalePregnancyLactationBirth to 6 Months30 mg30 mg7-12 months75 mg75 mg1-3 years80 mg80 mg4-8 years130 mg130 mg9-13 years240 mg240 mg14-18 years410 mg360 mg400 mg360 mg19-30 years400 mg310 mg350 mg310 mg31-50 + years420 mg320 mg360 mg320 mgThere are no official recommendations for how much magnesium to take specifically to relieve joint pain. But, since around half of Americans consume less than the RDI for magnesium, ensuring you meet the RDI for your age is a great place to start.Risks and Side EffectsIf you havetoo much magnesiumin your blood it’s calledhypermagnesemia. Having too much magnesium in the body can cause side effects.Symptoms of having too much magnesium include:VomitingMuscle weakness, reduced muscle tone (flaccid paralysis)Loss of appetiteNumbnessStrokeKidney diseaseSeizuresHow Magnesium Levels Are TestedSummaryThe body needs magnesium to function. Many parts of the body, from the nerves to the bones, need magnesium to work.One of the things magnesium can do is reduce inflammation. For this reason, it might help some people with certain kinds of arthritis.Magnesium can come from foods and/or supplements. Being deficient in magnesium can cause symptoms, but so can having too much magnesium.12 Foods to Eat If You Have Arthritis

There are no official recommendations for how much magnesium to take specifically to relieve joint pain. But, since around half of Americans consume less than the RDI for magnesium, ensuring you meet the RDI for your age is a great place to start.

If you havetoo much magnesiumin your blood it’s calledhypermagnesemia. Having too much magnesium in the body can cause side effects.

Symptoms of having too much magnesium include:

How Magnesium Levels Are Tested

Summary

The body needs magnesium to function. Many parts of the body, from the nerves to the bones, need magnesium to work.

One of the things magnesium can do is reduce inflammation. For this reason, it might help some people with certain kinds of arthritis.

Magnesium can come from foods and/or supplements. Being deficient in magnesium can cause symptoms, but so can having too much magnesium.

12 Foods to Eat If You Have Arthritis

20 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

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Nielsen FH.Magnesium deficiency and increased inflammation: current perspectives.J Inflamm Res. 2018;11:25-34. doi:10.2147/JIR.S136742

Razak MA, Begum PS, Viswanath B, Rajagopal S.Multifarious beneficial effect of nonessential amino acid, glycine: A review.Oxid Med Cell Longev. 2017 Mar;2017(1):1716701. doi:10.1155/2017/1716701

Oregon State University.Magnesium.

Koriem K, Tharwat H.Malic acid improves behavioral, biochemical, and molecular disturbances in the hypothalamus of stressed rats.J Integr Neurosci. 2023 Jul;22(4):98. doi:10.31083/j.jin2204098

Qiang F.Effect of malate-oligosaccharide solution on antioxidant capacity of endurance athletes.Open Biomed Eng J. 2015 Oct;9(1):326–329. doi:10.2174/1874120701509010326

Schaffer S, Kim HW.Effects and mechanisms of taurine as a therapeutic agent.Biomol Ther (Seoul). 2018 May;26(3):225-241. doi:10.4062/biomolther.2017.251

Li G, Cheng T, Yu X.The impact of trace elements on osteoarthritis.Front Med (Lausanne). 2021 Dec;8(1):771297. doi:10.3389/fmed.2021.771297

National Institutes of Health.Magnesium.

Veronese N, Stubbs B, Solmi M, et al.Dietary magnesium intake and fracture risk: data from a large prospective study.BJN. 2017 Jun;117(11):1570-1576. doi:10.1017/S0007114517001350

Shahi A, Aslani S, Ataollahi M, Mahmoudi M.The role of magnesium in different inflammatory diseases.Inflammopharmacology. 2019 Jun;27(1):649–661. doi:10.1007/s10787-019-00603-7

Centers for Disease Control.Rheumatoid arthritis.

Hu C, Zhu F, Liu L, Zhang M, Chen G.Relationship between dietary magnesium intake andrheumatoid arthritis in US women: a cross-sectional study.BMJ Open. 2020;10(11):e039640. doi:10.1136/bmjopen-2020-039640

Morel V, Pickering ME, Goubayon J, Djobo M, Macian N, Pickering G.Magnesium for pain treatment in 2021? State of the art.Nutrients. 2021 Apr;13(5):1397. doi:10.3390/nu13051397

Boulis M, Boulis M, Clauw D.Magnesium and fibromyalgia: A literature review.JPCCH. 2021;12(1). doi:10.1177/21501327211038433

Saint Luke’s.New research suggests magnesium and vitamin D can help reduce COVID-19 infections.

Marcuzzi A, Melloni E, Zauli G, et al.Autoinflammatory diseases cytokine storms—imbalances of innate and adaptive immunity.Int J Mol Sci. 2021 Oct;22(20):11241. doi:10.3390/ijms222011241

Dalton LM, Ní Fhloinn DM, Gaydadzhieva GT, Mazurkiewicz OM, Leeson H, Wright CP.Magnesium in pregnancy.Nutr Rev. 2016;74(9):549-57. doi:10.1093/nutrit/nuw018.

DiNicolantonio J, O’Keefe J, Wilson W.Subclinical magnesium deficiency: A principal driver of cardiovascular disease and a public health crisis.Open Heart. 2018 Jan;5(1):e000668. doi:10.1136/openhrt-2017-000668

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