Table of ContentsView AllTable of ContentsLife Expectancy TodayHow to Live LongerBarriers to LongevityAging With HIVLate DiagnosesAvoiding ComplicationsHow to Find Support

Table of ContentsView All

View All

Table of Contents

Life Expectancy Today

How to Live Longer

Barriers to Longevity

Aging With HIV

Late Diagnoses

Avoiding Complications

How to Find Support

People with HIV can expect to live a near-normal life expectancy if diagnosed and treated early. With advances inantiretroviral therapy, people living with HIV can expect to live longer and healthier than ever before if treatment is started at the time of diagnosis and taken as prescribed.

With that said, many factors can take back those gains and shorten a person’s life expectancy. Some you can change, such as smoking and injecting drugs, and some you can’t, like race and gender.

At the same time, non-HIV-related conditions like diabetes, heart disease, and cancer are more common in people with HIV. This makes it all the more important to reduce your risk for those diseases in order to live a longer, more healthy life.

An illustration with information about life expectancy of people living with hiv

Changes in Life Expectancy With HIV

Whenhighly active antiretroviral therapy (HAART)was first introduced in 1996, the average life expectancy of a 20-year-old newly infected with HIV was 10 years from the time of diagnosis.This new drug strategy—which involved the combination of multiple drugs of different classes—proved so effective that death rates rapidly dropped and life expectancies rapidly increased.

According to a 2013 study from the North American AIDS Cohort Collaboration on Research and Design, a 20-year-old starting HIV therapy could expect to live to their early 70s.

That figure was confirmed in a 2023 review published inLancet HIVin which the average life expectancy was reported to be anywhere from 70.8 years to 74.6 years for a 20-year-old newly diagnosed with HIV in North America and Europe.

With the life expectancy of the general U.S. population hovering at 77 years, this means that people treated early for HIV can enjoy near-normal lifespans. Some individuals can expect to live even longer.

How to Increase Life Expectancy

There are four things you can do to live a long, healthy life if recently diagnosed with HIV:

Delayed Treatment Reduces Longevity

Factors That Affect Life Expectancy

Despite advances in diagnosis and treatment, there are factors that can increase or decrease the life expectancy of people living with HIV. They include:

How HIV Affects You as You Age

With age, health concerns about HIV extend beyond just HIV-related illnesses. Even if HIV treatment is successful, the risk of non-HIV-associated diseases is exponentially greater than that of the general population.

So serious are these concerns that a person living with HIV today is far more likely todie prematurelyof a non-HIV-related illness than an HIV-related one.

That said, HIV infection may increase your risk of:

Drug-Induced Kidney and Bone DiseaseIt is important to note that certain antiretroviral drugs are associated with an increased risk of kidney dysfunction and osteoporosis. Chief among these is tenofovir found in the drugsTruvada, Descovy, Viread, Complera, Stribild, Atripla, Delstrigo, Symfi, and Symfi Lo.It is for this reason that people on tenofovir need to have their blood routinely checked withkidney function tests.Males 50 and older, postmenopausal females, and people at high risk of falls should undergo abone scanand discontinue tenofovir use if bone loss is significant.

Drug-Induced Kidney and Bone Disease

It is important to note that certain antiretroviral drugs are associated with an increased risk of kidney dysfunction and osteoporosis. Chief among these is tenofovir found in the drugsTruvada, Descovy, Viread, Complera, Stribild, Atripla, Delstrigo, Symfi, and Symfi Lo.It is for this reason that people on tenofovir need to have their blood routinely checked withkidney function tests.Males 50 and older, postmenopausal females, and people at high risk of falls should undergo abone scanand discontinue tenofovir use if bone loss is significant.

It is important to note that certain antiretroviral drugs are associated with an increased risk of kidney dysfunction and osteoporosis. Chief among these is tenofovir found in the drugsTruvada, Descovy, Viread, Complera, Stribild, Atripla, Delstrigo, Symfi, and Symfi Lo.

It is for this reason that people on tenofovir need to have their blood routinely checked withkidney function tests.Males 50 and older, postmenopausal females, and people at high risk of falls should undergo abone scanand discontinue tenofovir use if bone loss is significant.

Quality of Life

Even with newer drugs offering fewer side effects and simpler dosing schedules, people living with HIV still face significant challenges over the long term.

Even with excellent adherence, antiretroviral therapy can eventually fail and require a whole new set of drugs, some of which may be less tolerable. The cost of ongoing care and treatment can cause financial burdens and undue stress.

Moreover, the impact of stigma—which affects 82% of people living with HIV—can lead to social isolation that reduces not only the quality of life but also the ability to adhere to treatment.

Dealing with these concerns is seen to be just as important as getting a viral load to undetectable levels.

HIV Diagnosis in Older Adults

Older adults are more likely than younger adults to be diagnosed with HIV in the late stages of the disease,often when theimmune system is compromisedand the CD4 count is below 200 (theclinical definition of AIDS). For many in this situation, the diagnosis is made only after a person has had their first major opportunistic infection.

The problem with this is that older age and a low CD4 count at the time of diagnosis decrease the odds of restoring your CD4 count to normal levels. This, in turn, can affect your long-term survival.

Because HIV is often symptom-free until severe illness occurs, the U.S. Preventive Services Task Force recommends the once-off testing of HIV for all Americans ages 15 to 65 as part of a routine medical visit.

Testing is especially crucial if you haverisk factors for HIV, such as a history of multiple sex partners, condomless sex, or injection drug use.

Late Diagnoses in Older AdultsAccording to a 2023 report from the Centers for Disease Control and Prevention, 34% of people aged 55 and older already had late-stage HIV infection (AIDS) at the time of their diagnosis.

Late Diagnoses in Older Adults

According to a 2023 report from the Centers for Disease Control and Prevention, 34% of people aged 55 and older already had late-stage HIV infection (AIDS) at the time of their diagnosis.

Reducing the Risk of Developing AIDS

The best way to avoid a diagnosis of AIDS is to start antiretroviral therapy. This involves two or more drugs used in combination that block stages in the virus' life cycle. By doing so, the virus cannot make copies of itself, and the viral population can be reduced to undetectable levels where it can do the body little harm.

Most antiretroviral therapies come in pill form. Many are fixed-dose combination drugs that combine multiple antiretrovirals, reducing your dose to as little as one pill per day.

Dosing has even been made simpler with the introduction ofCabenuva, an antiretroviral therapy requiring two injections in the buttocks every two months.

Even if your diagnosis is delayed, it still benefits your health and longevity to start treatment immediately. If your CD4 count is low, your healthcare provider can prescribeprophylactic (preventive) drugsthat help reduce the risk of different opportunistic infections.

How Long Can I Live Without Treatment?According to a 2021 study in theJournal of the International AIDS Society,the average life expectancy for an untreated 24-year-old with HIV is 12.5 years, and 7.2 years for an untreated 45-year-old with HIV.Once AIDS is diagnosed, an untreated person will live for approximately three years.Fortunately, with appropriate treatment, a person with HIV may never develop AIDS or severe HIV-related complications.

How Long Can I Live Without Treatment?

According to a 2021 study in theJournal of the International AIDS Society,the average life expectancy for an untreated 24-year-old with HIV is 12.5 years, and 7.2 years for an untreated 45-year-old with HIV.Once AIDS is diagnosed, an untreated person will live for approximately three years.Fortunately, with appropriate treatment, a person with HIV may never develop AIDS or severe HIV-related complications.

According to a 2021 study in theJournal of the International AIDS Society,the average life expectancy for an untreated 24-year-old with HIV is 12.5 years, and 7.2 years for an untreated 45-year-old with HIV.Once AIDS is diagnosed, an untreated person will live for approximately three years.

Fortunately, with appropriate treatment, a person with HIV may never develop AIDS or severe HIV-related complications.

How to Get Support

Ensuring the longest possible life with HIV requires a commitment to therapy. This means taking your pills every day, making sure your prescriptions are refilled, and staying linked to consistent medical care.

These include:

It also helps to build a network of friends and confidants to support you or to join anHIV support groupavailable online or in person.

Summary

Studies show that people living with HIV today can expect to live a near-normal life expectancy if treatment is started early and taken every day as prescribed. Even so, some factors can undermine a person’s ability to do so.

Poverty, stigma, and racism can stand in a person’s way of accessing care and treatment. Other behaviors like smoking and injecting drug use are directly linked to a loss of life years.

Delayed treatment also reduces life expectancy because the immune system is less likely to recover, leaving the body vulnerable to infection.

Starting treatment early, staying on treatment, seeing your healthcare provider regularly, and maintaining a healthy lifestyle contribute to living a long life with HIV.

26 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Marcus JL, Chao CR, Leyden WA, et al.Narrowing the gap in life expectancy between HIV-infected and HIV-uninfected individuals with access to care.JAIDS.2016;73(1):39-46. doi:10.1097/QAI.0000000000001014

The Antiretroviral Therapy Cohort Collaboration.Survival of HIV-positive patients starting antiretroviral therapy between 1996 and 2013: a collaborative analysis of cohort studies.Lancet HIV.2017 Aug;4(8):e349–56. doi:10.1016/S2352-3018(17)30066-8

Samji H, Cescon A, Hogg RS, et al.Closing the gap: Increases in life expectancy among treated HIV-positive individuals in the United States and Canada.PLoS ONE. 2013;8(12):e81355. doi:10.1371/journal.pone.0081355

Trickey A, Sabin CA, Burkholder G, et al.Life expectancy after 2015 of adults with HIV on long-term antiretroviral therapy in Europe and North America: a collaborative analysis of cohort studies.Lancet HIV.2023 May;10(5):e295–e307. doi:10.1016/S2352-3018(23)00028-0

National Center for Health Statistics.Life expectancy.

Ulloa AC, Puskas C, Yip B, et al.Retention in care and mortality trends among patients receiving comprehensive care for HIV infection: a retrospective cohort study.CMAJ Open.2019 Apr-Jun;7(2):E236–E245. doi:10.9778/cmajo.20180136

Helleberg M, Afzal S, Kronborg G, et al.Mortality attributable to smoking among HIV-1–infected individuals: a nationwide, population-based cohort study.Clin Infect Dis.2013;56(5):727-734. doi:10.1093/cid/cis933

Mohammadi-Moein HR, Maracy MR. Tayeri K.Life expectancy after HIV diagnosis based on data from the counseling center for behavioral diseases.J Res Med Sci.2013 Dec;18(12):1040–1045.

Wang SC, Maher B.Substance use disorder, intravenous injection, and HIV infection: a review.Cell Transplant.2019 Dec;28(12): 1465–1471. doi:10.1177/0963689719878380

May MT, Gompels M, Delpech V, et al.Impact on life expectancy of HIV-1 positive individuals of CD4+ cell count and viral load response to antiretroviral therapy.AIDS. 2014;28(8):1193-202. doi:10.1097/QAD.0000000000000243

Kalichman SC, Hernandez D, Kegler C, Cheery C, Kalichman MO, Grebler T.Dimensions of poverty and health outcomes among people living with HIV infection: limited resources and competing needs.J Community Health.2015 Aug;40(4):702–708. doi:10.1007/s10900-014-9988-6

Edmond A, Breskin A, Cole S, et al.Poverty, deprivation, and mortality risk among women with HIV in the United States.Epidemiology.2021 Nov 1;32(6):877–885. doi:10.1097/EDE.0000000000001409

Borrell M, Fernandez I, Etcheverrry F, et al.High rates of long‐term progression in HIV‐1‐positive elite controllers.J Int AIDS Soc.2021 Feb;24(2):e25675. doi:10.1002/jia2.25675

De Coninck, Hussain-Alkhateeb L, Bratt G, et al.Non-AIDS mortality Is higher among successfully treated people living with HIV compared with matched HIV-negative control persons: a 15-Year follow-up cohort study in Sweden.AIDS Patient Care STDS.2018 Aug 1;32(8):297–305. doi:10.1089/apc.2018.0015

HIV.gov.What are some other health conditions associated with HIV?

Saylor D, Dickens AM Sacktor N, et al.HIV-associated neurocognitive disorder — pathogenesis and prospects for treatment.Nat Rev Neurol.2016 Apr;12(4):234–248. doi:10.1038/nrneurol.2016.27

Brown TT, Hoy J Borderi M, et al.Recommendations for evaluation and management of bone disease in HIV.Clin Infect Dis.2015 Apr 15;60(8):1242–1251. doi:10.1093/cid/civ010

Murungi A, et al.Experience of living with HIV: diagnosis & disclosure - findings from the Positive Perspective Study. IAS Conference on HIV Science; 23-26 July 201y; Paris, France. Abstract: WEPED1423

HIV.gov.Aging with HIV.

U.S. Preventive Services Task Force.Final recommendation statement: human immunodeficiency virus (HIV) infection: screening.

Centers for Disease Control and Prevention.National HIV prevention and care outcomes.

HIVinfo.NIH.gov.HIV treatment: the basics.

U.S. .S. Food and Drug Administration.FDA approves first extended-release, injectable drug regimen for adults living with HIV.

Glaubius R, Kothegal N, Birhanu S, et al.Disease progression and mortality with untreated HIV infection: evidence synthesis of HIV seroconverter cohorts, antiretroviral treatment clinical cohorts and population-based survey data.J Int AIDS Soc. 2021 Sep;24 Suppl 5(Suppl 5):e25784. doi:10.1002/jia2.2578

HIV.gov.What are HIV and AIDS?

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