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Back in 1999, researchers appearing in theAmerican Journal of Obstetrics and Gynecologyrecommended the addition of androgen (testosterone) to estrogen for all women undergoing surgical menopause.
Today, it’s still a treatment that healthcare providers offer to women struggling with the natural effects of menopause. And some research has shown that testosterone can, in fact, provide the following benefits to women:
But though androgen therapy has been around since 1936, many women are still wary about it. In the past, there have been reports of side effects such as hoarseness or other voice changes, or the development of facial hair, acne, or hypersexuality. And longterm safety information on testosterone/androgen therapy is lacking.Then came the results of the Women’s Health Initiative, a multi-year study on the long-term use of hormones to prevent chronic diseases such as cognitive decline orcardiovascular disease. One study from as recently as 2002 found that combination progesterone and estrogen therapy caused an increased risk for invasive breast cancer, which is likely to be the reason the FDA has been slow in approving other hormones like testosterone for women.
Symptoms of Testosterone Deficiency
Still, healthcare providers continue to prescribe its usage off-label, and the pharmaceutical industry certainly hasn’t discouraged them from doing so. Among the symptoms they cite are:
If you have been experiencing any of these symptoms over a long span of time, and it has been causing you personal distress, you should certainly talk to your gynecologist or primary care healthcare provider. If they can’t help, they may be able to refer you to another medical practitioner who specializes in female sexual functioning, or to another sexuality professional.
Luckily, there are so many options these days. And the North American Menopause Society has even put together a free app called MenoPro that looks at a woman’s health history and offers guidance for what women can do.
In the end, the best thing you can do is due diligence. Do your own research. Talk to your healthcare provider. Consider all of the risks and benefits.
And then choose the option that’s best for you.
4 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Sarrel PM.Psychosexual effects of menopause: Role of androgens.American Journal of Obstetrics and Gynecology. 1999;180(3). doi:10.1016/s0002-9378(99)70727-1.Achilli C, Pundir J, Ramanathan P, Sabatini L, Hamoda H, Panay N.Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis.Fertil Steril.2017;107(2):475-482.e15.Wierman ME, Arlt W, Basson R, et al.Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline.J Clin Endocrinol Metab. 2014;99(10):3489-510. doi:10.1210/jc.2014-2260Writing Group For The Womens Health Initiative Investigators.Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Womens Health Initiative Randomized Controlled Trial.JAMA: The Journal of the American Medical Association. 2002;288(3):321-333. doi:10.1001/jama.288.3.321
4 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Sarrel PM.Psychosexual effects of menopause: Role of androgens.American Journal of Obstetrics and Gynecology. 1999;180(3). doi:10.1016/s0002-9378(99)70727-1.Achilli C, Pundir J, Ramanathan P, Sabatini L, Hamoda H, Panay N.Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis.Fertil Steril.2017;107(2):475-482.e15.Wierman ME, Arlt W, Basson R, et al.Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline.J Clin Endocrinol Metab. 2014;99(10):3489-510. doi:10.1210/jc.2014-2260Writing Group For The Womens Health Initiative Investigators.Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Womens Health Initiative Randomized Controlled Trial.JAMA: The Journal of the American Medical Association. 2002;288(3):321-333. doi:10.1001/jama.288.3.321
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Sarrel PM.Psychosexual effects of menopause: Role of androgens.American Journal of Obstetrics and Gynecology. 1999;180(3). doi:10.1016/s0002-9378(99)70727-1.Achilli C, Pundir J, Ramanathan P, Sabatini L, Hamoda H, Panay N.Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis.Fertil Steril.2017;107(2):475-482.e15.Wierman ME, Arlt W, Basson R, et al.Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline.J Clin Endocrinol Metab. 2014;99(10):3489-510. doi:10.1210/jc.2014-2260Writing Group For The Womens Health Initiative Investigators.Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Womens Health Initiative Randomized Controlled Trial.JAMA: The Journal of the American Medical Association. 2002;288(3):321-333. doi:10.1001/jama.288.3.321
Sarrel PM.Psychosexual effects of menopause: Role of androgens.American Journal of Obstetrics and Gynecology. 1999;180(3). doi:10.1016/s0002-9378(99)70727-1.
Achilli C, Pundir J, Ramanathan P, Sabatini L, Hamoda H, Panay N.Efficacy and safety of transdermal testosterone in postmenopausal women with hypoactive sexual desire disorder: a systematic review and meta-analysis.Fertil Steril.2017;107(2):475-482.e15.
Wierman ME, Arlt W, Basson R, et al.Androgen therapy in women: a reappraisal: an Endocrine Society clinical practice guideline.J Clin Endocrinol Metab. 2014;99(10):3489-510. doi:10.1210/jc.2014-2260
Writing Group For The Womens Health Initiative Investigators.Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: Principal Results From the Womens Health Initiative Randomized Controlled Trial.JAMA: The Journal of the American Medical Association. 2002;288(3):321-333. doi:10.1001/jama.288.3.321
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