Table of ContentsView AllTable of ContentsWhat Is Gallbladder Disease?What to EatVitamins and SupplementsOther Remedies
Table of ContentsView All
View All
Table of Contents
What Is Gallbladder Disease?
What to Eat
Vitamins and Supplements
Other Remedies
Magnesium, dandelion, and vitamins C and E may all be beneficial in preventing gallbladder disease. However, research evidence is not yet strong enough to suggest the use of any vitamin, mineral, or herb to boost gallbladder health.
There is scientific proof, however, that a well-balanced diet plays a crucial role in the digestive organ’s health. Focusing on fiber and healthy fats—while limiting refined carbohydrates and trans fats—may be an effective way to prevent gallbladder disease.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
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There are many types ofgallbladder disease. However, the most common gallbladder issue isgallstones, which may occur when substances in the bile harden and block the bile ducts.
Types of gallbladder disease include:
Symptoms of gallbladder disease vary and may depend on the diagnosis.
The most common symptom of gallbladder disease is pain. Typically, this pain is intermittent and occurs in the upper right abdomen.
Other gallbladder disease symptoms include:
If you have persistent gallstones or severe gallbladder disease, the most likely treatment may be surgery. Gallbladder removal is typically performed as an outpatient procedure and may be performedlaparoscopically.You can live a normal life without a gallbladder.
In mild cases of gallbladder disease, a healthcare provider may recommend over-the-counter (OTC) or prescription pain medications. Other medications may also treat various symptoms.
More natural treatment approaches are another possible option. For example, diet changes and certain supplements for gallbladder disease may prove helpful.
Your diet plays a critical role in your gallbladder’s health.
Remember that your gallbladder releases bile you need to digest fats. This makes your gallbladder a key player in digestion. Due to this role, what you eat affects your gallbladder and how it functions.
Evidence shows that a well-balanced diet may lower the risk of gallstones and other types of gallbladder disease.
Certain foods, like meats, fried foods, and refined carbohydrates, have been linked to gallstone formation, especially when eaten in excess. High intake ofsaturated fatsmay also make gallstones more likely.
For gallstone prevention and overall gallbladder health:
If necessary, a registered dietitian and nutritionist (RD or RDN) can help you learn how to alter your diet and lifestyle for gallbladder health.
Certain dietary supplements, including vitamins, minerals, and herbs, may prove beneficial for gallbladder disease.
However, no supplement will completely heal your gallbladder on its own. Supplements should only complement other treatment options for any health condition, including gallbladder disease.
Despite anecdotal evidence and various claims, research results are mixed regarding the effectiveness of supplements for gallbladder disease.
Below is a look at the scientific evidence surrounding vitamins, minerals, herbs, and other supplements for gallbladder disease.
Magnesium
Magnesiumis often touted as a remedy for gallstones. However, there is limited scientific evidence to support this claim.
Some studies from the early 2000s supported taking magnesium supplements for gallstones and other gallbladder issues. A 2008 study suggested that men who consumed more magnesium were less likely to have gallstones.
However, since then, researchers have conducted few studies on magnesium for gallbladder health.
A more recent study from 2021 found a potential role for magnesium in the prevention ofgallbladder cancer. In the lab study, degradable magnesium prohibited the growth of gallbladder cancer and even killed cancer cells.
However, at this time, these results have not been duplicated in humans. More research on magnesium for gallbladder disease is necessary.
Dandelion
Dandelion(Taraxacum officinale) is an herb that has been used in folk medicine for a variety of gastrointestinal disorders.
Dandelion is known to contain bioactive substances likebeta-sitosterol, caffeic acid,taraxerol, andpolysaccharidesthat are thought to provide gastrointestinal protective benefits. Studies have found these and other dandelion substances to be beneficial for gallstones.
Proponents claim that dandelion root increases the flow of bile, which may help prevent gallstones and other disorders. However, no solid scientific evidence supports this. More research is necessary.
Vitamin C
As an antioxidant,vitamin Cis often taken to protect against oxidative stress and various health conditions.
There is some evidence thatvitamin C supplementsmay protect against some types of gallbladder disease, but the number of relevant studies supporting this is lacking overall.
A dated observational study found a possible relationship between vitamin C intake and gallstones. In the study of over 2,000 adults, those who reported regular vitamin C consumption had lower rates of gallstones than those who reported low vitamin C consumption. Researchers concluded that vitamin C might protect against gallstones.
A much smaller and more recent study found similar results, concluding that vitamin C supplementation may reduce cholesterol crystallization, and thus, gallstone formation.
A third study found that low levels of vitamin C and other antioxidants may increase the risk of cholecystitis (gallbladder infection).
Stronger, well-designed studies are necessary to determine the role of vitamin C in gallbladder disease. As it stands now, the evidence is too weak to make any definitive recommendation.
Vitamin E
Vitamin Eis a fat-soluble vitamin and antioxidant that may protect you from getting gallstones.
In one study of over 500 adults, researchers hypothesized that vitamin E levels in the blood would be inversely associated with gallstones. Participants agreed to have their blood drawn to assess their vitamin E status. Gallstones were also detected via ultrasound.
The results showed that participants with gallstone disease had lower vitamin E levels compared to those who didn’t have the disease. Likewise, higher vitamin E levels were linked to a lower risk of gallstone disease.
Few other studies of the effects of vitamin E on gallbladder disease exist. Overall, research in this area is limited, and more studies are necessary.
Caffeine
Some research points tocaffeineas a natural remedy for gallstones.
According to one systematic review, coffee consumption is associated with a lower risk of gallstones. Studies have also found that gallstone risk decreases the more coffee you drink.
An observational study looked at how high coffee consumption affects the risk of gallstones. By analyzing over 100,000 members of the general population, researchers were able to conclude that drinking 2 to 6 cups of coffee per day may protect against gallstones.
That other studies on gallbladder disease have found no benefits from caffeine use is worth noting.
Though coffee can be beneficial, remember that consuming too much caffeine can become dangerous. Adults should generally limit themselves to a maximum of 400 milligrams of caffeine per day, which is about 4 or 5 cups of coffee.
Milk Thistle
Milk thistle(Silybum marianum) is a medicinal plant with many purported benefits.
Milk thistle has been used for centuries as a natural treatment for gallstones.Silymarin, one of the main active components in milk thistle, is thought to be responsible for any beneficial effects on gallstones.
However, no available studies explain how milk thistle may protect against gallstones. Well-designed studies are necessary to prove whether milk thistle has any role in gallstone prevention.
Other Ways to Relieve Gallbladder Disease Symptoms
You may be able to relieve certain symptoms of gallbladder disease with some minimally invasive treatments, especially if your disease is mild. However, severe or persistent cases of gallbladder disease may require surgery.
Lifestyle changes may be the first necessary step intreating gallbladder disease. An overall well-balanced diet plus regular physical activity is thought to lower the risk of gallstones. It’s also important to maintain a healthy weight for your body type.
Many people with gallbladder disease experience pain. Fortunately, there are various ways to treat mild to moderate pain.
OTC pain medications are commonly recommended for gallbladder pain. Other options for pain treatment include hot and cold compresses.
Additionally, research is emerging on the use ofacupuncturefor gallbladder disease management. Some studies have shown that acupuncture may relieve symptoms of various types of gallbladder disease, including gallstones andcholecystitis.
Summary
Your gallbladder stores bile, a liquid-like substance your body needs to digest fats. Sometimes, things can go wrong with your gallbladder, leading to gallbladder disease.
In addition to standard care, complementary treatment options are available for gallbladder disease, including lifestyle changes and dietary supplements that may relieve symptoms or prevent the disease.
Overall, more research on the effectiveness of most supplements for gallbladder disease is necessary. Talk with a healthcare provider to learn if supplements are a safe choice for you.
20 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
MedlinePlus.Gallbladder disease.
Johns Hopkins Medicine.Gallbladder disease.
Park Y, Kim D, Lee JS, et al.Association between diet and gallstones of cholesterol and pigment among patients with cholecystectomy: a case-control study in Korea.J Health Popul Nutr. 2017;36(1):39. doi:10.1186/s41043-017-0116-y
National Institute of Diabetes and Digestive and Kidney Diseases.Eating, diet, & nutrition for gallstones.
Tsai CJ, Leitzmann MF, Willett WC, Giovannucci EL.Long-term effect of magnesium consumption on the risk of symptomatic gallstone disease among men.Am J Gastroenterol. 2008;103(2):375-382. doi:10.1111/j.1572-0241.2007.01696.x
Peng H, Fan K, Zan R, et al.Degradable magnesium implants inhibit gallbladder cancer.Acta Biomaterialia. 2021;128:514-522. doi:10.1016/j.actbio.2021.04.051
National Center for Complementary and Integrative Health.Dandelion.
Li Y, Chen Y, Sun-Waterhouse D.The potential of dandelion in the fight against gastrointestinal diseases: a review.J Ethnopharmacol. 2022;293:115272. doi:10.1016/j.jep.2022.115272
Walcher T, Haenle MM, Kron M, et al.Vitamin C supplement use may protect against gallstones: an observational study on a randomly selected population.BMC Gastroenterol. 2009;9:74. doi:10.1186/1471-230X-9-74
del Pozo R, Muñoz M, Dumas A, et al.Effects of vitamin C administration on cholesterol gallstone formation.Rev Med Chil. 2014;142(1):20-26. doi:10.4067/S0034-98872014000100004
Miao C, Xiao L, Xu X, et al.Circulating vitamin levels mediate the causal relationship between gut microbiota and cholecystitis: a two-step bidirectional Mendelian randomization study.Front Nutr. 2023;10:1268893. doi:10.3389/fnut.2023.1268893
Waniek S, di Giuseppe R, Esatbeyoglu T, et al.Association of circulating vitamin E (α- and γ-Tocopherol) levels with gallstone disease.Nutrients. 2018;10(2):133. doi:10.3390/nu10020133
Zhang YP, Li WQ, Sun YL, et al.Systematic review with meta-analysis: coffee consumption and the risk of gallstone disease.Aliment Pharmacol Ther. 2015;42(6):637-648. doi:10.1111/apt.13328
Nordestgaard AT, Stender S, Nordestgaard BG, Tybjaerg-Hansen A.Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study.J Intern Med. 2020;287(1):42-53. doi:10.1111/joim.12970
Larsson SC, Giovannucci EL, Wolk A.Coffee consumption and risk of gallbladder cancer in a prospective study.J Natl Cancer Inst. 2017;109(3):1-3. doi:10.1093/jnci/djw237
U.S. Food and Drug Administration.Spilling the beans: how much caffeine is too much?
Khazaei R, Seidavi A, Bouyeh M.A review on the mechanisms of the effect of silymarin in milk thistle (Silybum marianum) on some laboratory animals.Vet Med Sci. 2022;8(1):289-301. doi:10.1002/vms3.641
Zhong G, Luo Y, Chi Z, et al.Clinical acupuncture therapy for chronic cholecystitis: a protocol for systematic review and meta-analysis.Medicine (Baltimore). 2021;100(10):e24994. doi:10.1097/MD.0000000000024994
Sun N, Zhou YF, Zhou J, et al.The cerebral mechanism underlying the acupoints with specific effect for gallbladder stone disease: protocol for a randomized controlled task-fMRI trial.Trials. 2021;22(1):399. doi:10.1186/s13063-021-05356-9
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