Table of ContentsView AllTable of ContentsFibromyalgia Leg PainNeuropathyRestless Legs SyndromeITB SyndromeMyofascial Pain SyndromeAutoimmune DiseasesFrequently Asked Questions

Table of ContentsView All

View All

Table of Contents

Fibromyalgia Leg Pain

Neuropathy

Restless Legs Syndrome

ITB Syndrome

Myofascial Pain Syndrome

Autoimmune Diseases

Frequently Asked Questions

Fibromyalgiacan cause pain anywhere, includingleg pain. Some common overlapping conditions can cause or contribute to leg pain, as well. This can make it hard to recognize pain from other sources rather than writing them off as just part of fibromyalgia.

This article explores causes of leg pain that may be related to fibromyalgia or that may come from a different condition, the symptoms to watch for, and how different types of leg pain are treated.

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A physical therapist works on a patient’s leg

Fibromyalgia causesabnormal pain typesthat can strike the legs. These include:

Leg pain from these causes may feel like fibromyalgia pains in the rest of your body or it may have a different quality.

If your leg pain is from fibromyalgia, your healthcare provider will NOT find physical abnormalities such as joint wear and tear, a lot of inflammation, heat, or redness. X-rays and imaging studies will show what looks like healthy bones and tissues.

That doesn’t mean the pain isn’t real—it is. However, it’s in the nerves themselves and not the tissues.This makes fibromyalgia different from other pain conditions such asrheumatoid arthritisandlupus.

Treating Fibromyalgia Leg Pain

Leg pain from fibromyalgia should go away when your fibromyalgia is properly treated. Treatment options include:

It takes time and experimentation to come up with the right combination of treatments for you.

Neuropathyis pain from nerve damage. Some studies suggest fibromyalgia may involve certain types of nerve damage.Also,diabetesis common in people with fibromyalgia and can cause neuropathy.

Symptoms of neuropathy include:

To diagnose neuropathy in your legs, your healthcare provider may use:

Treating Neuropathy

Common treatments for neuropathy include:

Neuropathy can’t be cured, but it can often be well managed.

The sensations are often described as throbbing, creeping, or pulling. In many people, these sensations aren’t painful. However, in fibromyalgia, the brain interprets all unpleasant sensations as painful.

Some people with RLS also have uncontrollable leg movements, such as jerking, while asleep or awake and relaxing.

No diagnostic tests can identify RLS so it’s typically diagnosed based on your symptoms and tests to rule out other possible causes.

Treating Restless Legs Syndrome

In those cases, treating the underlying condition may alleviate RLS.

Other treatment options include:

The iliotibial band (ITB) is a strong band of tissue that runs from hip to knee. When it’s aggravated, you may developITB syndrome(or “runner’s knee”).

The pain of ITB syndrome usually starts on the outside of your knee. It may spread up the thigh clear to the hip, as well. It may be especially noticeable when you go up or down stairs.

It’s unknown whether ITB syndrome is more common in people with fibromyalgia. However, studies show fibromyalgia involves lax connective tissues and hypermobile joints,which may make conditions like ITB syndrome more likely.

Healthcare providers often diagnose ITB syndrome based on symptoms and a physical exam. If they’re not sure what’s causing the pain, they may order imaging tests, too.

Treating ITB Syndrome

Treatment strategies for ITB syndrome include:

If these measures don’t alleviate your knee pain, your healthcare provider may recommend surgery that can help.

Myofascial pain syndrome(MPS) involvestrigger points—taut areas in connective tissues that radiate pain to other areas. Trigger points in the legs are common. Many people with fibromyalgia also have MPS.

Symptoms of MPS include:

MPS doesn’t have a diagnostic test. It’s diagnosed based on:

Comparing Fibromyalgia and MPS

Treating Myofascial Pain Syndrome

Inautoimmune diseases, your immune system mistakenly identifies a healthy part of your body as a threat, such as a virus or bacterium. It then creates specialized cells called antibodies that attack and try to destroy that particular part.

Contemporary research suggests fibromyalgia may be an autoimmune disease.Whether it is or not, it’s established that some autoimmune diseases, such as rheumatoid arthritis, make you more likely to develop fibromyalgia.

That was once thought to be a one-way relationship. Now, though, newer research suggests fibromyalgia may predispose you to autoimmunity.

Dozens of different autoimmune diseases exist, all with different targets. Autoimmune diseases that could cause leg pain include:

Blood tests for antibodies are often used to diagnose autoimmune diseases. Other tests vary depending on what your healthcare provider suspects.

Sjögren’s Disease in Fibromyalgia

Treating Autoimmune Disease

Treatment depends on which autoimmune disease you have.

However, the most common treatment is immunosuppressants or immunomodulators, (medications that suppress or change immune system activity). By calming the immune system, these drugs scale back the attack on your body.

Common immunosuppressants/immunomodulators include:

Other treatments may replace something the body can no longer produce on its own, such asthyroid hormonesorinsulin, or help manage symptoms.

Summary

Treatment depends on your diagnosis. It may include medications, physical therapy, lifestyle changes, and CAM treatments.

A Word From Verywell

Leg pain can affect your mobility and have a big impact on daily life. Don’t think you just have to live with it—talk to your healthcare provider about what might be causing it. If it’s not “just” another fibromyalgia symptom, you may be able to treat it successfully.

Frequently Asked QuestionsFibromyalgia causes pain throughout the body, so leg pain is a common symptom.If pain is only in your legs, however, it’s not fibromyalgia. By definition, fibromyalgia pain is widespread, meaning it’s on both sides of the body and above and below the waist.It’s impossible to predict how long any fibromyalgia symptom will last. It’s a chronic (long-lasting) condition, but symptoms fluctuate over time and change with treatment.A common description of fibromyalgia pain is “a migraine all over your body.” Pain may be sharp, dull, burning, achy, “zingy,” pins-and-needles, constant, intermittent, or any combination of those. It may also move around the body or generally stay in the same places.

Fibromyalgia causes pain throughout the body, so leg pain is a common symptom.If pain is only in your legs, however, it’s not fibromyalgia. By definition, fibromyalgia pain is widespread, meaning it’s on both sides of the body and above and below the waist.

Fibromyalgia causes pain throughout the body, so leg pain is a common symptom.

If pain is only in your legs, however, it’s not fibromyalgia. By definition, fibromyalgia pain is widespread, meaning it’s on both sides of the body and above and below the waist.

It’s impossible to predict how long any fibromyalgia symptom will last. It’s a chronic (long-lasting) condition, but symptoms fluctuate over time and change with treatment.

A common description of fibromyalgia pain is “a migraine all over your body.” Pain may be sharp, dull, burning, achy, “zingy,” pins-and-needles, constant, intermittent, or any combination of those. It may also move around the body or generally stay in the same places.

32 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Maugars Y, Berthelot JM, Le Goff B, Darrieutort-Laffite C.Fibromyalgia and associated disorders: From pain to chronic suffering, from subjective hypersensitivity to hypersensitivity syndrome.Front Med (Lausanne). 2021;8:666914. Published 2021 Jul 14. doi:10.3389/fmed.2021.666914Häuser W, Fitzcharles MA.Facts and myths pertaining to fibromyalgia.Dialogues Clin Neurosci. 2018;20(1):53-62. doi:10.31887/DCNS.2018.20.1/whauserMartínez-Lavín M.Dorsal root ganglia: fibromyalgia pain factory?.Clin Rheumatol. 2021;40(2):783-787. doi:10.1007/s10067-020-05528-zAmerican College of Rheumatology.Fibromyalgia.National Institutes of Health, National Center for Complementary and Integrative Health.Fibromyalgia: In depth.Cameron EC, Hemingway SL.Cannabinoids for fibromyalgia pain: a critical review of recent studies (2015-2019).J Cannabis Res. 2020;2(1):19. Published 2020 May 29. doi:10.1186/s42238-020-00024-2Boehnke KF, Gagnier JJ, Matallana L, Williams DA.Substituting cannabidiol for opioids and pain medications among individuals with fibromyalgia: A large online survey.J Pain. 2021;22(11):1418-1428. doi:10.1016/j.jpain.2021.04.011Martínez-Lavín M.Fibromyalgia and small fiber neuropathy: the plot thickens!.Clin Rheumatol. 2018;37(12):3167-3171. doi:10.1007/s10067-018-4300-2Maffei ME.Fibromyalgia: Recent advances in diagnosis, classification, pharmacotherapy and alternative remedies.Int J Mol Sci. 2020;21(21):7877. Published 2020 Oct 23. doi:10.3390/ijms21217877Australian Government, Department of Health and Aged Care: HealthDirect.Nerve pain (neuralgia).Johns Hopkins Medicine.Peripheral neuropathy.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Staud R, Godfrey MM, Robinson ME.Fibromyalgia patients are not only hypersensitive to painful stimuli but also to acoustic stimuli.J Pain. 2021;22(8):914-925. doi:10.1016/j.jpain.2021.02.009National Institutes of Health, U.S. National Library of Medicine: MedlinePlus.Restless legs syndrome.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Cedars Sinai.Iliotibial band syndrome.Eccles JA, Thompson B, Themelis K, et al.Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study.Clin Med (Lond). 2021;21(1):53-58. doi:10.7861/clinmed.2020-0743Vulfsons S, Minerbi A.The case for comorbid myofascial pain-A qualitative review.Int J Environ Res Public Health. 2020;17(14):5188. Published 2020 Jul 17. doi:10.3390/ijerph17145188American Society of Anesthesiologists: Made for This Moment.Myofascial pain syndrome.Tracey KJ.From human to mouse and back offers hope for patients with fibromyalgia.J Clin Invest. 2021;131(13):e150382. doi:10.1172/JCI150382Roodenrijs NMT, van der Goes MC, Welsing PMJ, et al.Difficult-to-treat rheumatoid arthritis: contributing factors and burden of disease.Rheumatology (Oxford). 2021;60(8):3778-3788. doi:10.1093/rheumatology/keaa860Gau SY, Leong PY, Lin CL, Tsou HK, Wei JC.Higher risk for Sjögren’s syndrome in patients with fibromyalgia: A nationwide population-based cohort study.Front Immunol. 2021;12:640618. Published 2021 Apr 12. doi:10.3389/fimmu.2021.640618Arthritis Foundation.Rheumatoid arthritis: Causes, symptoms, treatments and more.Centers for Disease Control and Prevention.Symptoms of lupus.MS Society.Pain.Versus Arthritis.What is ankylosing spondylitis?Versus Arthritis.What is myositis?Arthritis Foundation.Sjögren’s syndrome.U.S. Department of Health & Human Services, Office on Women’s Health.Autoimmune diseases.American Academy of Allergy, Asthma & Immunology.Immunosuppressive medication for the treatment of autoimmune disease.Arthritis Foundation.Fibromyalgia.Bartley EJ, Robinson ME, Staud R.Pain and fatigue variability patterns distinguish subgroups of fibromyalgia patients.J Pain. 2018;19(4):372-381. doi:10.1016/j.jpain.2017.11.014

32 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Maugars Y, Berthelot JM, Le Goff B, Darrieutort-Laffite C.Fibromyalgia and associated disorders: From pain to chronic suffering, from subjective hypersensitivity to hypersensitivity syndrome.Front Med (Lausanne). 2021;8:666914. Published 2021 Jul 14. doi:10.3389/fmed.2021.666914Häuser W, Fitzcharles MA.Facts and myths pertaining to fibromyalgia.Dialogues Clin Neurosci. 2018;20(1):53-62. doi:10.31887/DCNS.2018.20.1/whauserMartínez-Lavín M.Dorsal root ganglia: fibromyalgia pain factory?.Clin Rheumatol. 2021;40(2):783-787. doi:10.1007/s10067-020-05528-zAmerican College of Rheumatology.Fibromyalgia.National Institutes of Health, National Center for Complementary and Integrative Health.Fibromyalgia: In depth.Cameron EC, Hemingway SL.Cannabinoids for fibromyalgia pain: a critical review of recent studies (2015-2019).J Cannabis Res. 2020;2(1):19. Published 2020 May 29. doi:10.1186/s42238-020-00024-2Boehnke KF, Gagnier JJ, Matallana L, Williams DA.Substituting cannabidiol for opioids and pain medications among individuals with fibromyalgia: A large online survey.J Pain. 2021;22(11):1418-1428. doi:10.1016/j.jpain.2021.04.011Martínez-Lavín M.Fibromyalgia and small fiber neuropathy: the plot thickens!.Clin Rheumatol. 2018;37(12):3167-3171. doi:10.1007/s10067-018-4300-2Maffei ME.Fibromyalgia: Recent advances in diagnosis, classification, pharmacotherapy and alternative remedies.Int J Mol Sci. 2020;21(21):7877. Published 2020 Oct 23. doi:10.3390/ijms21217877Australian Government, Department of Health and Aged Care: HealthDirect.Nerve pain (neuralgia).Johns Hopkins Medicine.Peripheral neuropathy.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Staud R, Godfrey MM, Robinson ME.Fibromyalgia patients are not only hypersensitive to painful stimuli but also to acoustic stimuli.J Pain. 2021;22(8):914-925. doi:10.1016/j.jpain.2021.02.009National Institutes of Health, U.S. National Library of Medicine: MedlinePlus.Restless legs syndrome.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Cedars Sinai.Iliotibial band syndrome.Eccles JA, Thompson B, Themelis K, et al.Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study.Clin Med (Lond). 2021;21(1):53-58. doi:10.7861/clinmed.2020-0743Vulfsons S, Minerbi A.The case for comorbid myofascial pain-A qualitative review.Int J Environ Res Public Health. 2020;17(14):5188. Published 2020 Jul 17. doi:10.3390/ijerph17145188American Society of Anesthesiologists: Made for This Moment.Myofascial pain syndrome.Tracey KJ.From human to mouse and back offers hope for patients with fibromyalgia.J Clin Invest. 2021;131(13):e150382. doi:10.1172/JCI150382Roodenrijs NMT, van der Goes MC, Welsing PMJ, et al.Difficult-to-treat rheumatoid arthritis: contributing factors and burden of disease.Rheumatology (Oxford). 2021;60(8):3778-3788. doi:10.1093/rheumatology/keaa860Gau SY, Leong PY, Lin CL, Tsou HK, Wei JC.Higher risk for Sjögren’s syndrome in patients with fibromyalgia: A nationwide population-based cohort study.Front Immunol. 2021;12:640618. Published 2021 Apr 12. doi:10.3389/fimmu.2021.640618Arthritis Foundation.Rheumatoid arthritis: Causes, symptoms, treatments and more.Centers for Disease Control and Prevention.Symptoms of lupus.MS Society.Pain.Versus Arthritis.What is ankylosing spondylitis?Versus Arthritis.What is myositis?Arthritis Foundation.Sjögren’s syndrome.U.S. Department of Health & Human Services, Office on Women’s Health.Autoimmune diseases.American Academy of Allergy, Asthma & Immunology.Immunosuppressive medication for the treatment of autoimmune disease.Arthritis Foundation.Fibromyalgia.Bartley EJ, Robinson ME, Staud R.Pain and fatigue variability patterns distinguish subgroups of fibromyalgia patients.J Pain. 2018;19(4):372-381. doi:10.1016/j.jpain.2017.11.014

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Maugars Y, Berthelot JM, Le Goff B, Darrieutort-Laffite C.Fibromyalgia and associated disorders: From pain to chronic suffering, from subjective hypersensitivity to hypersensitivity syndrome.Front Med (Lausanne). 2021;8:666914. Published 2021 Jul 14. doi:10.3389/fmed.2021.666914Häuser W, Fitzcharles MA.Facts and myths pertaining to fibromyalgia.Dialogues Clin Neurosci. 2018;20(1):53-62. doi:10.31887/DCNS.2018.20.1/whauserMartínez-Lavín M.Dorsal root ganglia: fibromyalgia pain factory?.Clin Rheumatol. 2021;40(2):783-787. doi:10.1007/s10067-020-05528-zAmerican College of Rheumatology.Fibromyalgia.National Institutes of Health, National Center for Complementary and Integrative Health.Fibromyalgia: In depth.Cameron EC, Hemingway SL.Cannabinoids for fibromyalgia pain: a critical review of recent studies (2015-2019).J Cannabis Res. 2020;2(1):19. Published 2020 May 29. doi:10.1186/s42238-020-00024-2Boehnke KF, Gagnier JJ, Matallana L, Williams DA.Substituting cannabidiol for opioids and pain medications among individuals with fibromyalgia: A large online survey.J Pain. 2021;22(11):1418-1428. doi:10.1016/j.jpain.2021.04.011Martínez-Lavín M.Fibromyalgia and small fiber neuropathy: the plot thickens!.Clin Rheumatol. 2018;37(12):3167-3171. doi:10.1007/s10067-018-4300-2Maffei ME.Fibromyalgia: Recent advances in diagnosis, classification, pharmacotherapy and alternative remedies.Int J Mol Sci. 2020;21(21):7877. Published 2020 Oct 23. doi:10.3390/ijms21217877Australian Government, Department of Health and Aged Care: HealthDirect.Nerve pain (neuralgia).Johns Hopkins Medicine.Peripheral neuropathy.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Staud R, Godfrey MM, Robinson ME.Fibromyalgia patients are not only hypersensitive to painful stimuli but also to acoustic stimuli.J Pain. 2021;22(8):914-925. doi:10.1016/j.jpain.2021.02.009National Institutes of Health, U.S. National Library of Medicine: MedlinePlus.Restless legs syndrome.National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.Cedars Sinai.Iliotibial band syndrome.Eccles JA, Thompson B, Themelis K, et al.Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study.Clin Med (Lond). 2021;21(1):53-58. doi:10.7861/clinmed.2020-0743Vulfsons S, Minerbi A.The case for comorbid myofascial pain-A qualitative review.Int J Environ Res Public Health. 2020;17(14):5188. Published 2020 Jul 17. doi:10.3390/ijerph17145188American Society of Anesthesiologists: Made for This Moment.Myofascial pain syndrome.Tracey KJ.From human to mouse and back offers hope for patients with fibromyalgia.J Clin Invest. 2021;131(13):e150382. doi:10.1172/JCI150382Roodenrijs NMT, van der Goes MC, Welsing PMJ, et al.Difficult-to-treat rheumatoid arthritis: contributing factors and burden of disease.Rheumatology (Oxford). 2021;60(8):3778-3788. doi:10.1093/rheumatology/keaa860Gau SY, Leong PY, Lin CL, Tsou HK, Wei JC.Higher risk for Sjögren’s syndrome in patients with fibromyalgia: A nationwide population-based cohort study.Front Immunol. 2021;12:640618. Published 2021 Apr 12. doi:10.3389/fimmu.2021.640618Arthritis Foundation.Rheumatoid arthritis: Causes, symptoms, treatments and more.Centers for Disease Control and Prevention.Symptoms of lupus.MS Society.Pain.Versus Arthritis.What is ankylosing spondylitis?Versus Arthritis.What is myositis?Arthritis Foundation.Sjögren’s syndrome.U.S. Department of Health & Human Services, Office on Women’s Health.Autoimmune diseases.American Academy of Allergy, Asthma & Immunology.Immunosuppressive medication for the treatment of autoimmune disease.Arthritis Foundation.Fibromyalgia.Bartley EJ, Robinson ME, Staud R.Pain and fatigue variability patterns distinguish subgroups of fibromyalgia patients.J Pain. 2018;19(4):372-381. doi:10.1016/j.jpain.2017.11.014

Maugars Y, Berthelot JM, Le Goff B, Darrieutort-Laffite C.Fibromyalgia and associated disorders: From pain to chronic suffering, from subjective hypersensitivity to hypersensitivity syndrome.Front Med (Lausanne). 2021;8:666914. Published 2021 Jul 14. doi:10.3389/fmed.2021.666914

Häuser W, Fitzcharles MA.Facts and myths pertaining to fibromyalgia.Dialogues Clin Neurosci. 2018;20(1):53-62. doi:10.31887/DCNS.2018.20.1/whauser

Martínez-Lavín M.Dorsal root ganglia: fibromyalgia pain factory?.Clin Rheumatol. 2021;40(2):783-787. doi:10.1007/s10067-020-05528-z

American College of Rheumatology.Fibromyalgia.

National Institutes of Health, National Center for Complementary and Integrative Health.Fibromyalgia: In depth.

Cameron EC, Hemingway SL.Cannabinoids for fibromyalgia pain: a critical review of recent studies (2015-2019).J Cannabis Res. 2020;2(1):19. Published 2020 May 29. doi:10.1186/s42238-020-00024-2

Boehnke KF, Gagnier JJ, Matallana L, Williams DA.Substituting cannabidiol for opioids and pain medications among individuals with fibromyalgia: A large online survey.J Pain. 2021;22(11):1418-1428. doi:10.1016/j.jpain.2021.04.011

Martínez-Lavín M.Fibromyalgia and small fiber neuropathy: the plot thickens!.Clin Rheumatol. 2018;37(12):3167-3171. doi:10.1007/s10067-018-4300-2

Maffei ME.Fibromyalgia: Recent advances in diagnosis, classification, pharmacotherapy and alternative remedies.Int J Mol Sci. 2020;21(21):7877. Published 2020 Oct 23. doi:10.3390/ijms21217877

Australian Government, Department of Health and Aged Care: HealthDirect.Nerve pain (neuralgia).

Johns Hopkins Medicine.Peripheral neuropathy.

National Institutes of Health, National Institute of Neurological Disorders and Stroke.Restless legs syndrome.

Staud R, Godfrey MM, Robinson ME.Fibromyalgia patients are not only hypersensitive to painful stimuli but also to acoustic stimuli.J Pain. 2021;22(8):914-925. doi:10.1016/j.jpain.2021.02.009

National Institutes of Health, U.S. National Library of Medicine: MedlinePlus.Restless legs syndrome.

Cedars Sinai.Iliotibial band syndrome.

Eccles JA, Thompson B, Themelis K, et al.Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study.Clin Med (Lond). 2021;21(1):53-58. doi:10.7861/clinmed.2020-0743

Vulfsons S, Minerbi A.The case for comorbid myofascial pain-A qualitative review.Int J Environ Res Public Health. 2020;17(14):5188. Published 2020 Jul 17. doi:10.3390/ijerph17145188

American Society of Anesthesiologists: Made for This Moment.Myofascial pain syndrome.

Tracey KJ.From human to mouse and back offers hope for patients with fibromyalgia.J Clin Invest. 2021;131(13):e150382. doi:10.1172/JCI150382

Roodenrijs NMT, van der Goes MC, Welsing PMJ, et al.Difficult-to-treat rheumatoid arthritis: contributing factors and burden of disease.Rheumatology (Oxford). 2021;60(8):3778-3788. doi:10.1093/rheumatology/keaa860

Gau SY, Leong PY, Lin CL, Tsou HK, Wei JC.Higher risk for Sjögren’s syndrome in patients with fibromyalgia: A nationwide population-based cohort study.Front Immunol. 2021;12:640618. Published 2021 Apr 12. doi:10.3389/fimmu.2021.640618

Arthritis Foundation.Rheumatoid arthritis: Causes, symptoms, treatments and more.

Centers for Disease Control and Prevention.Symptoms of lupus.

MS Society.Pain.

Versus Arthritis.What is ankylosing spondylitis?

Versus Arthritis.What is myositis?

Arthritis Foundation.Sjögren’s syndrome.

U.S. Department of Health & Human Services, Office on Women’s Health.Autoimmune diseases.

American Academy of Allergy, Asthma & Immunology.Immunosuppressive medication for the treatment of autoimmune disease.

Arthritis Foundation.Fibromyalgia.

Bartley EJ, Robinson ME, Staud R.Pain and fatigue variability patterns distinguish subgroups of fibromyalgia patients.J Pain. 2018;19(4):372-381. doi:10.1016/j.jpain.2017.11.014

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