Table of ContentsView AllTable of ContentsBreast Pain & the COVID-19 VaccineEffects on Mammogram ResultsNon-COVID Causes of Breast PainRelieving PainFrequently Asked Questions
Table of ContentsView All
View All
Table of Contents
Breast Pain & the COVID-19 Vaccine
Effects on Mammogram Results
Non-COVID Causes of Breast Pain
Relieving Pain
Frequently Asked Questions
Vaccinescan causeside effectssuch as headaches, fever, or joint pain. The most common side effect of the COVID-19 vaccine is injection site soreness.
There are also reports of axillary (armpit) pain near the breast on the side of theCOVID-19 vaccination. Mammograms (breast cancer screening) have also detected swollen lymph nodes after the injection. While this may sound alarming, these are known side effects of the COVID-19 vaccine, and they resolve on their own.
This article covers breast pain as a side effect of the COVID-19 vaccine, its impact on mammogram results, non-vaccine causes for breast pain, and how to find relief.
Panuwat Dangsungnoen / Getty Images
Top 20 Vaccines You Should Know About
Breast Pain: A Side Effect After COVID-19 Vaccine
Breast pain is a possible side effect of several vaccines, includinginfluenza(flu) or the humanpapillomavirus(HPV).But it appears more frequently as a side effect of the COVID-19 vaccine.
Moderna and Pfizer reported lymph node swelling and underarm tenderness as side effects during their clinical trials for the novel COVID-19 mRNA vaccination.
Around 11% of people who received the Moderna vaccine had lymph node swelling and tenderness after the first shot and 16% after the second. Pfizer trials showed 0.3% of their trial participants reported these side effects.
Vaccines trigger a normal response in the immune system, which can cause side effects such as swelling, joint pain, or a mild fever. This response is usually the cause of breast pain after the COVID-19 vaccine.
Underarm tenderness and swollenlymphnodes in the armpit area may occur with breast pain. Similar to injection site soreness, these side effects are usually on the same side where the shot was given.They can appear as early as one day after the vaccine.
What Are Lymph Nodes?Lymph nodesare part of thelymphatic systemwithin theimmune system. They are small, bean-sized organs that trap pathogens (things that make you sick such as bacteria and viruses). This prevents the pathogens from circulating throughout the body.Swollen lymph nodesare often a part of the immune response.
What Are Lymph Nodes?
Lymph nodesare part of thelymphatic systemwithin theimmune system. They are small, bean-sized organs that trap pathogens (things that make you sick such as bacteria and viruses). This prevents the pathogens from circulating throughout the body.Swollen lymph nodesare often a part of the immune response.
Antibodies From Vaccines vs. Antibodies From Natural Infection
How Long It Lasts
Breast pain typically resolves within two days of getting the Moderna vaccine and 10 days of getting the Pfizer vaccine. These are average times, and there are reports of these side effects lasting more than six weeks.
Other Possible Breast Changes
When breast pain is a side effect of the COVID-19 vaccine, there is no cause for alarm. It does not indicate any health problems and will resolve on its own. If it doesn’t resolve within a few days of the vaccine, notify your healthcare provider.
Breast pain can also be a breast cancer symptom, making this side effect alarming for many people.However, breast pain as a symptom of breast cancer is rare. Studies report a 1% to 7% chance of cancer being the cause of breast pain.
Breast Changes That May Occur With Breast CancerOften, breast cancer is a silent disease, meaning there are no symptoms. When there are symptoms, they may include the following breast changes:A new lump in the breast or underarmThickening or swelling in the breastBreast skin irritation or dimplingNipple pain or pullingRedness or flakiness in the nipple area or breastNipple discharge (other than expected breast milk), this includes bloodChanges in breast size or shapeBreast pain
Breast Changes That May Occur With Breast Cancer
Often, breast cancer is a silent disease, meaning there are no symptoms. When there are symptoms, they may include the following breast changes:A new lump in the breast or underarmThickening or swelling in the breastBreast skin irritation or dimplingNipple pain or pullingRedness or flakiness in the nipple area or breastNipple discharge (other than expected breast milk), this includes bloodChanges in breast size or shapeBreast pain
Often, breast cancer is a silent disease, meaning there are no symptoms. When there are symptoms, they may include the following breast changes:
Lymph node swelling in the armpit is a normal reaction to the COVID-19 vaccine. However, it causes suspicion when it’s amammogramfinding, as it can be mistaken for a sign of breast cancer.
When COVID-19 vaccine side effects cause thesemammogram findings, it can lead to unnecessary worry and testing. Ideally, it’s best to get a mammogram before the vaccine. But, if you do have a mammogram shortly after the COVID-19 vaccine, notify the mammogram technician.
If you have suspected breast cancer or are getting breast cancer treatment, it’s best to receive the vaccine on the arm opposite of the possible or confirmed breast cancer.
While breast pain typically resolves within the average times mentioned above, lymph node swelling could still appear on a mammogram for up to 43 weeks. One study showed that:
These studies note much higher percentages than the clinical trials. This is likely because the trial participants self-reported lymph node swelling during clinical trials, but the study used mammogram findings instead. This indicates that swollen lymph nodes could appear on a mammogram for quite some time after the symptoms you feel resolve.
Should I Postpone a Mammogram After a COVID-19 Vaccine?Initially, there was a recommendation to wait six to eight weeks after the vaccine to get a mammogram. But professional organizations, such as the Radiological Society of North America, no longer recommend delaying mammogram screenings after the COVID-19 vaccination.
Should I Postpone a Mammogram After a COVID-19 Vaccine?
Initially, there was a recommendation to wait six to eight weeks after the vaccine to get a mammogram. But professional organizations, such as the Radiological Society of North America, no longer recommend delaying mammogram screenings after the COVID-19 vaccination.
Where the CDC Stands
The Centers for Disease Control and Prevention (CDC) states that the COVID-19 vaccine side effects are generally mild and go away within a few days. They list the most common side effects as follows:
Breast pain and lymph node swelling are not listed as common side effects, but the CDC notes that they occur.
Non-vaccine-relatedbreast painis a common complaint and affects up to 70% to 80% of women.
Cyclic breast paintypically affects both breasts and may cause underarm soreness. Hormones are the culprit for this type of breast pain. It’s a tender or heavy feeling that comes and goes based on your menstrual cycle (period).
Noncyclic breast painis not related to your menstrual cycle. It does not come and go and may cause sharp or burning pain. This pain occurs on one side and typically stays in the same place.
Breast Pain and Your Menstrual Period: Is It Normal?
Relief for Post-Vaccine Breast Pain
Relief for post-vaccine breast pain is similar to relieving injection site swelling and tenderness. You can try the following techniques:
OTC Medications and the COVID-19 VaccineThe CDC recommends continuing your OTC medications if you currently take them. If you don’t regularly take OTC pain relievers, it’s best to wait until you get your vaccine rather than take them for prevention.However, most of the studies that have investigated use of these medications before or after receiving a vaccine have not found that they impact the efficacy of the vaccine.
OTC Medications and the COVID-19 Vaccine
The CDC recommends continuing your OTC medications if you currently take them. If you don’t regularly take OTC pain relievers, it’s best to wait until you get your vaccine rather than take them for prevention.However, most of the studies that have investigated use of these medications before or after receiving a vaccine have not found that they impact the efficacy of the vaccine.
The CDC recommends continuing your OTC medications if you currently take them. If you don’t regularly take OTC pain relievers, it’s best to wait until you get your vaccine rather than take them for prevention.
However, most of the studies that have investigated use of these medications before or after receiving a vaccine have not found that they impact the efficacy of the vaccine.
Summary
Vaccines can cause side effects such as a mild fever or headache. The most common symptom of the COVID-19 vaccination is soreness at the injection (shot) site.
While breast pain is not the most common vaccine side effect, it can occur with some vaccines. It seems to be more common in the COVID-19 vaccine than in others.
The COVID-19 vaccine can also cause lymph node swelling under the arm. This can create a false positive on amammogram(breast cancer screening), which can cause stress and unnecessary testing.
Breast pain is a common complaint among those assigned female at birth. It can result from hormones, poorly fitting bras, large breasts, and more.
A Word From Verywell
If a mammogram and COVID-19 vaccine are in your near future, it may be best to wait to get the vaccine until a day or two after the mammogram. If you’ve already had the shot, let the mammogram technician know before the procedure.
Regardless, don’t delay your mammogram.Breast cancer screeningsare life-saving. They lead to early detection, diagnosis, and treatment which typically means a better outcome.
Frequently Asked QuestionsLittle is known about whether COVID-19 affects breast cancer. Some early studies showed COVID-19 might affect a particular stage of a tumor’s life cycle, but more research is needed.Learn MoreBreast Cancer and the COVID-19 Vaccine: Is It Safe?COVID-19 can impact multiple organs, including the lungs, heart, kidneys, liver, skin, and brain.Learn MoreUnderstanding the 11 Body Organ SystemsSome people developlong COVID, which is a condition in which symptoms linger. Researchers are still determining why this happens and which groups of people are at higher risk of getting long COVID.Learn MoreNew Criteria Helps Predict Which COVID-19 Patients Experience Cytokine Storm
Little is known about whether COVID-19 affects breast cancer. Some early studies showed COVID-19 might affect a particular stage of a tumor’s life cycle, but more research is needed.Learn MoreBreast Cancer and the COVID-19 Vaccine: Is It Safe?
Little is known about whether COVID-19 affects breast cancer. Some early studies showed COVID-19 might affect a particular stage of a tumor’s life cycle, but more research is needed.
Learn MoreBreast Cancer and the COVID-19 Vaccine: Is It Safe?
COVID-19 can impact multiple organs, including the lungs, heart, kidneys, liver, skin, and brain.Learn MoreUnderstanding the 11 Body Organ Systems
COVID-19 can impact multiple organs, including the lungs, heart, kidneys, liver, skin, and brain.
Learn MoreUnderstanding the 11 Body Organ Systems
Some people developlong COVID, which is a condition in which symptoms linger. Researchers are still determining why this happens and which groups of people are at higher risk of getting long COVID.Learn MoreNew Criteria Helps Predict Which COVID-19 Patients Experience Cytokine Storm
Some people developlong COVID, which is a condition in which symptoms linger. Researchers are still determining why this happens and which groups of people are at higher risk of getting long COVID.
Learn MoreNew Criteria Helps Predict Which COVID-19 Patients Experience Cytokine Storm
16 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Centers for Disease Control and Prevention.Vaccines and immunizations: reactions and adverse events.Lam DL, Flanagan MR.Axillary lymphadenopathy after COVID-19 vaccination in a woman with breast cancer.JAMA.2022;327(2):175–176. doi:10.1001/jama.2021.20010Hao M, Edmonds C, Nachiappan A, et al.Management strategies for patients presenting with symptomatic lymphadenopathy and breast edema after recent COVID-19 vaccination.American Journal of Roentgenology. 2022;218(6):970-976. doi:10.2214/AJR.21.27118Becker AS, Perez-Johnston R, Chikarmane SA, et al.Multidisciplinary recommendations regarding post-vaccine adenopathy and radiologic imaging: Radiology scientific expert panel.Radiology. 2021;300(2):E323-E327. doi:10.1148/radiol.2021210436Wolfson S, Kim E, Plaunova A, et al.Axillary adenopathy after COVID-19 vaccine: no reason to delay screening mammogram. Radiology. 2022:303(2):297–299. doi:10.1148/radiol.213227Eren T, Aslan A, Ozemir I, et al.Factors effecting mastalgia.Breast care (Basel). 2016;11(3):188-193. doi:10.1159/000444359Sivarajah R, Welkie J, Mack J, et al.A review of breast pain: causes, imaging recommendations, and treatment.Journal of Breast Imaging. 2020;2(2):101-111. doi:10.1093/jbi/wbz082Centers for Disease Control and Prevention.Breast cancer: what are the symptoms?Radiological Society of North America.No need to delay mammogram after the COVID vaccine.Centers for Disease Control and Prevention.COVID-19: possible side effects.Salzman B, Collins E, Hersh L.Common breast problems.Am Fam Physician. 2019;99(8):505-514.Centers for Disease Control and Prevention.Getting Your COVID-19 Vaccine.Laughey W, Lodhi I, Pennick G, Smart L, Sanni O, Sandhu S, Charlesworth B.Ibuprofen, other NSAIDs and COVID-19: a narrative review. Inflammopharmacology. 2023 Oct;31(5):2147-2159. doi: 10.1007/s10787-023-01309-7Francescangeli F, De Angelis ML, Zeuner, A.COVID-19: a potential driver of immune-mediated breast cancer recurrence.Breast Cancer Res.2020;22(117). doi:10.1186/s13058-020-01360-0Al-Benna S.Angiotensin-converting enzyme 2 gene expression in breast tissue.Eur J Breast Health. 2021; 17(2):112–115. doi:10.4274/ejbh.galenos.2021.6007Centers for Disease Control and Prevention.Long COVID.
16 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Centers for Disease Control and Prevention.Vaccines and immunizations: reactions and adverse events.Lam DL, Flanagan MR.Axillary lymphadenopathy after COVID-19 vaccination in a woman with breast cancer.JAMA.2022;327(2):175–176. doi:10.1001/jama.2021.20010Hao M, Edmonds C, Nachiappan A, et al.Management strategies for patients presenting with symptomatic lymphadenopathy and breast edema after recent COVID-19 vaccination.American Journal of Roentgenology. 2022;218(6):970-976. doi:10.2214/AJR.21.27118Becker AS, Perez-Johnston R, Chikarmane SA, et al.Multidisciplinary recommendations regarding post-vaccine adenopathy and radiologic imaging: Radiology scientific expert panel.Radiology. 2021;300(2):E323-E327. doi:10.1148/radiol.2021210436Wolfson S, Kim E, Plaunova A, et al.Axillary adenopathy after COVID-19 vaccine: no reason to delay screening mammogram. Radiology. 2022:303(2):297–299. doi:10.1148/radiol.213227Eren T, Aslan A, Ozemir I, et al.Factors effecting mastalgia.Breast care (Basel). 2016;11(3):188-193. doi:10.1159/000444359Sivarajah R, Welkie J, Mack J, et al.A review of breast pain: causes, imaging recommendations, and treatment.Journal of Breast Imaging. 2020;2(2):101-111. doi:10.1093/jbi/wbz082Centers for Disease Control and Prevention.Breast cancer: what are the symptoms?Radiological Society of North America.No need to delay mammogram after the COVID vaccine.Centers for Disease Control and Prevention.COVID-19: possible side effects.Salzman B, Collins E, Hersh L.Common breast problems.Am Fam Physician. 2019;99(8):505-514.Centers for Disease Control and Prevention.Getting Your COVID-19 Vaccine.Laughey W, Lodhi I, Pennick G, Smart L, Sanni O, Sandhu S, Charlesworth B.Ibuprofen, other NSAIDs and COVID-19: a narrative review. Inflammopharmacology. 2023 Oct;31(5):2147-2159. doi: 10.1007/s10787-023-01309-7Francescangeli F, De Angelis ML, Zeuner, A.COVID-19: a potential driver of immune-mediated breast cancer recurrence.Breast Cancer Res.2020;22(117). doi:10.1186/s13058-020-01360-0Al-Benna S.Angiotensin-converting enzyme 2 gene expression in breast tissue.Eur J Breast Health. 2021; 17(2):112–115. doi:10.4274/ejbh.galenos.2021.6007Centers for Disease Control and Prevention.Long COVID.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Centers for Disease Control and Prevention.Vaccines and immunizations: reactions and adverse events.Lam DL, Flanagan MR.Axillary lymphadenopathy after COVID-19 vaccination in a woman with breast cancer.JAMA.2022;327(2):175–176. doi:10.1001/jama.2021.20010Hao M, Edmonds C, Nachiappan A, et al.Management strategies for patients presenting with symptomatic lymphadenopathy and breast edema after recent COVID-19 vaccination.American Journal of Roentgenology. 2022;218(6):970-976. doi:10.2214/AJR.21.27118Becker AS, Perez-Johnston R, Chikarmane SA, et al.Multidisciplinary recommendations regarding post-vaccine adenopathy and radiologic imaging: Radiology scientific expert panel.Radiology. 2021;300(2):E323-E327. doi:10.1148/radiol.2021210436Wolfson S, Kim E, Plaunova A, et al.Axillary adenopathy after COVID-19 vaccine: no reason to delay screening mammogram. Radiology. 2022:303(2):297–299. doi:10.1148/radiol.213227Eren T, Aslan A, Ozemir I, et al.Factors effecting mastalgia.Breast care (Basel). 2016;11(3):188-193. doi:10.1159/000444359Sivarajah R, Welkie J, Mack J, et al.A review of breast pain: causes, imaging recommendations, and treatment.Journal of Breast Imaging. 2020;2(2):101-111. doi:10.1093/jbi/wbz082Centers for Disease Control and Prevention.Breast cancer: what are the symptoms?Radiological Society of North America.No need to delay mammogram after the COVID vaccine.Centers for Disease Control and Prevention.COVID-19: possible side effects.Salzman B, Collins E, Hersh L.Common breast problems.Am Fam Physician. 2019;99(8):505-514.Centers for Disease Control and Prevention.Getting Your COVID-19 Vaccine.Laughey W, Lodhi I, Pennick G, Smart L, Sanni O, Sandhu S, Charlesworth B.Ibuprofen, other NSAIDs and COVID-19: a narrative review. Inflammopharmacology. 2023 Oct;31(5):2147-2159. doi: 10.1007/s10787-023-01309-7Francescangeli F, De Angelis ML, Zeuner, A.COVID-19: a potential driver of immune-mediated breast cancer recurrence.Breast Cancer Res.2020;22(117). doi:10.1186/s13058-020-01360-0Al-Benna S.Angiotensin-converting enzyme 2 gene expression in breast tissue.Eur J Breast Health. 2021; 17(2):112–115. doi:10.4274/ejbh.galenos.2021.6007Centers for Disease Control and Prevention.Long COVID.
Centers for Disease Control and Prevention.Vaccines and immunizations: reactions and adverse events.
Lam DL, Flanagan MR.Axillary lymphadenopathy after COVID-19 vaccination in a woman with breast cancer.JAMA.2022;327(2):175–176. doi:10.1001/jama.2021.20010
Hao M, Edmonds C, Nachiappan A, et al.Management strategies for patients presenting with symptomatic lymphadenopathy and breast edema after recent COVID-19 vaccination.American Journal of Roentgenology. 2022;218(6):970-976. doi:10.2214/AJR.21.27118
Becker AS, Perez-Johnston R, Chikarmane SA, et al.Multidisciplinary recommendations regarding post-vaccine adenopathy and radiologic imaging: Radiology scientific expert panel.Radiology. 2021;300(2):E323-E327. doi:10.1148/radiol.2021210436
Wolfson S, Kim E, Plaunova A, et al.Axillary adenopathy after COVID-19 vaccine: no reason to delay screening mammogram. Radiology. 2022:303(2):297–299. doi:10.1148/radiol.213227
Eren T, Aslan A, Ozemir I, et al.Factors effecting mastalgia.Breast care (Basel). 2016;11(3):188-193. doi:10.1159/000444359
Sivarajah R, Welkie J, Mack J, et al.A review of breast pain: causes, imaging recommendations, and treatment.Journal of Breast Imaging. 2020;2(2):101-111. doi:10.1093/jbi/wbz082
Centers for Disease Control and Prevention.Breast cancer: what are the symptoms?
Radiological Society of North America.No need to delay mammogram after the COVID vaccine.
Centers for Disease Control and Prevention.COVID-19: possible side effects.
Salzman B, Collins E, Hersh L.Common breast problems.Am Fam Physician. 2019;99(8):505-514.
Centers for Disease Control and Prevention.Getting Your COVID-19 Vaccine.
Laughey W, Lodhi I, Pennick G, Smart L, Sanni O, Sandhu S, Charlesworth B.Ibuprofen, other NSAIDs and COVID-19: a narrative review. Inflammopharmacology. 2023 Oct;31(5):2147-2159. doi: 10.1007/s10787-023-01309-7
Francescangeli F, De Angelis ML, Zeuner, A.COVID-19: a potential driver of immune-mediated breast cancer recurrence.Breast Cancer Res.2020;22(117). doi:10.1186/s13058-020-01360-0
Al-Benna S.Angiotensin-converting enzyme 2 gene expression in breast tissue.Eur J Breast Health. 2021; 17(2):112–115. doi:10.4274/ejbh.galenos.2021.6007
Centers for Disease Control and Prevention.Long COVID.
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