Table of ContentsView AllTable of ContentsBiology of StressDefinitionTypesCausesSymptomsComplicationsDiagnosisTreatmentNext in Stress GuideWhat Is Stress and How Can I Recognize It?

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Table of Contents

Biology of Stress

Definition

Types

Causes

Symptoms

Complications

Diagnosis

Treatment

Next in Stress Guide

Chronic stress is feeling pressured and overwhelmed over a long period. While occasional stress can provide you with the energy and focus needed to achieve more, ongoing stress can be detrimental to your health. This is because being stressed triggers the release of hormones calledcortisolandadrenaline (epinephrine)that alter the way your brain and body function.

Among other things, chronic stress has damaging effects on your blood vessels, increasing the risk of high blood pressure and heart disease It can also affect moods and sexual function while increasing the risk of stomach ulcers and upper respiratory infections.

This article describes the symptoms, causes, and complications of chronic stress. It also looks at how chronic stress is diagnosed and treated and what can be done to prevent it.

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Stressed businessman working on laptop at desk

The Biology of Stress

Stress is the body’s natural response to physical and psychological challenges or threats. It is part of a survival mechanism known as the “fight or flight” response in which hormones are released to provide the body with the energy and resources needed to either face the threat or flee it.

The release of these “stress hormones”—calledcortisolandadrenaline—triggers physiological changes to address the real or perceived threat.

When the flight-or-fight response is triggered:.

When the threat is over, the body will return to its natural balanced state. Stress under these circumstances is known asacute stress.

What Is Chronic Stress?

While stress is generally acute, rising and falling in response to stressors, there are times when the body will react as if the threat is ever-present. This is chronic stress.

With chronic stress, the persistent elevation of stress hormones throws the body off its natural balanced state. Over time, this can affect the body in adverse ways:

How Common Is Chronic Stress?According to the American Institute of Stress, 55% of people in the United States experience daily stress. Chronic stress is especially common in workplaces, with 94% of employees reporting work-related stress. Of these, 63% report wanting to quit their jobs because of stress.

How Common Is Chronic Stress?

According to the American Institute of Stress, 55% of people in the United States experience daily stress. Chronic stress is especially common in workplaces, with 94% of employees reporting work-related stress. Of these, 63% report wanting to quit their jobs because of stress.

Types of Chronic Stress

By definition, stress is chronic when it persists for weeks or months.The stress may be psycholological (related to the mind), physiological (related to the body), or both. Oftentimes, physiological stress (such as managing a severe illness) can lead to psychological stress.

Examples of psychological and physiological stressors associated with chronic stress include:

Being overworked

Financial hardship

Living in a noisy or chaotic environment

Relationship problems

Death of a loved one

Loneliness

Marriage or divorce

Lack of work/life balance

Anxiety or anxiety disorders

Physiological StressA major illness, like cancerA chronic illness, including chronic painPregnancyObesityMalnutritionGeneral poor health statusSubstance use, including alcohol abuseHeavy manual laborWorking in pollution, including industrial pollutantsFrequent long-distant air travel

A major illness, like cancer

A chronic illness, including chronic pain

Pregnancy

Obesity

Malnutrition

General poor health status

Substance use, including alcohol abuse

Heavy manual labor

Working in pollution, including industrial pollutants

Frequent long-distant air travel

Causes of Chronic Stress

Chronic stress does not affect all people equally. Certain social and psychological factors can predispose you to chronic stress, including:

Minority Stress and Health Disparities

Symptoms of Chronic Stress

Over the short term, chronic stress can induce many of the same symptoms of acute stress, albeit for longer periods. These include:

But what makes chronic stress distinct is that its symptoms are the result of prolonged exposure to cortisol and adrenaline. Over time, this can cause damage to organ systems, both directly and indirectly, leading to a cascade of possible symptoms, such as:

Complications of Chronic Stress

Left unchecked, chronic stress can start to impact multiple organ systems, including the brain, cardiovascular system, reproductive tract, and digestive tract.

Possible complications of chronic stress include:

How Stress Causes UlcersThe relationship between stress and stomach ulcers is strong. Chronic stress increases the secretion of stomach acids, in part because the normal balance of the digestive tract has been disrupted. High stomach acids, in turn, contribute to the formation of stomach ulcers.The risk is further increased if you takenonsteroidal anti-inflammatory drugs (NSAIDs)like aspirin, Advil (ibuprofen), or Aleve (naproxen), perhaps to manage stress-related headaches or symptoms like muscle pain. These drugs can promote ulcers and bleeding.

How Stress Causes Ulcers

The relationship between stress and stomach ulcers is strong. Chronic stress increases the secretion of stomach acids, in part because the normal balance of the digestive tract has been disrupted. High stomach acids, in turn, contribute to the formation of stomach ulcers.The risk is further increased if you takenonsteroidal anti-inflammatory drugs (NSAIDs)like aspirin, Advil (ibuprofen), or Aleve (naproxen), perhaps to manage stress-related headaches or symptoms like muscle pain. These drugs can promote ulcers and bleeding.

The relationship between stress and stomach ulcers is strong. Chronic stress increases the secretion of stomach acids, in part because the normal balance of the digestive tract has been disrupted. High stomach acids, in turn, contribute to the formation of stomach ulcers.

The risk is further increased if you takenonsteroidal anti-inflammatory drugs (NSAIDs)like aspirin, Advil (ibuprofen), or Aleve (naproxen), perhaps to manage stress-related headaches or symptoms like muscle pain. These drugs can promote ulcers and bleeding.

Diagnosing Chronic Stress

Chronic stress is not diagnosed in the same way as high blood pressure or anxiety. It is a characteristic used to describe a primary or contributing factor of a stress-related condition, like high blood pressure.

How Is Chronic Stress Treated?

The approach tostress managementis often multifaceted, including lifestyle changes, social support efforts, mindfulness, and seeking professional help.

Lifestyle

Some lifestyle changes you can make to help combat stress include:

Social Support

Social support efforts that can help combat stress include:

Relaxation

Though it’s easier said than done, relaxing can reduce stress. Some relaxation techniques include:

Other Practical Ways to Reduce StressGetting practical about how your lifestyle influences your stress levels can help. Ways to do this include:Identify your stressorsLook for solutionsMake a plan in advance for how to manage stress when it arises

Other Practical Ways to Reduce Stress

Getting practical about how your lifestyle influences your stress levels can help. Ways to do this include:Identify your stressorsLook for solutionsMake a plan in advance for how to manage stress when it arises

Getting practical about how your lifestyle influences your stress levels can help. Ways to do this include:

Professional Help

Chronic stress can’t always be effectively managed on your own. A mental health professional can help you with strategies through:

Depending on symptoms, antidepressant or anti-anxiety medication may also be prescribed. Discuss medication options with your healthcare provider if you think they could benefit your stress management plan.

Summary

Stress can be acute, chronic, or episodic. In the short term, stress is beneficial, allowing us to react to threatening situations and build resiliency. Chronic stress, however, is not helpful and can cause health concerns such as mental health conditions, gastrointestinal discomfort, and sleep difficulties. It is also associated with several health conditions, including heart disease and diabetes.

Approaches to chronic stress management include lifestyle practices, relaxation techniques, and social support. Some people may also find it helpful to see a healthcare provider or mental health professional.

9 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Russell G, Lightman S.The human stress response.Nat Rev Endocrinol. 2019;15(9):525-534. doi:10.1038/s41574-019-0228-0Centre for Studies of Human Stress.Biology of stress.American Institute of Stress.What is stress?MedlinePlus.Stress and your health.American Psychological Association.Stress effects on the body.American Psychological Association.Stress in America: our health at risk.Plummer MP, Blaser AR, Deane AM.Stress ulceration: prevalence, pathology and association with adverse outcomes.Crit Care.2014;18(2):213. doi:10.1186/cc13780Kalliomaki J, Jansen GB.Development of a chronic stress diagnosis.J Rehabil Med Clin Commun.2021;4:1000064. doi:10.2340/20030711-1000064Harvard Health.Six relaxation techniques to reduce stress.

9 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Russell G, Lightman S.The human stress response.Nat Rev Endocrinol. 2019;15(9):525-534. doi:10.1038/s41574-019-0228-0Centre for Studies of Human Stress.Biology of stress.American Institute of Stress.What is stress?MedlinePlus.Stress and your health.American Psychological Association.Stress effects on the body.American Psychological Association.Stress in America: our health at risk.Plummer MP, Blaser AR, Deane AM.Stress ulceration: prevalence, pathology and association with adverse outcomes.Crit Care.2014;18(2):213. doi:10.1186/cc13780Kalliomaki J, Jansen GB.Development of a chronic stress diagnosis.J Rehabil Med Clin Commun.2021;4:1000064. doi:10.2340/20030711-1000064Harvard Health.Six relaxation techniques to reduce stress.

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Russell G, Lightman S.The human stress response.Nat Rev Endocrinol. 2019;15(9):525-534. doi:10.1038/s41574-019-0228-0Centre for Studies of Human Stress.Biology of stress.American Institute of Stress.What is stress?MedlinePlus.Stress and your health.American Psychological Association.Stress effects on the body.American Psychological Association.Stress in America: our health at risk.Plummer MP, Blaser AR, Deane AM.Stress ulceration: prevalence, pathology and association with adverse outcomes.Crit Care.2014;18(2):213. doi:10.1186/cc13780Kalliomaki J, Jansen GB.Development of a chronic stress diagnosis.J Rehabil Med Clin Commun.2021;4:1000064. doi:10.2340/20030711-1000064Harvard Health.Six relaxation techniques to reduce stress.

Russell G, Lightman S.The human stress response.Nat Rev Endocrinol. 2019;15(9):525-534. doi:10.1038/s41574-019-0228-0

Centre for Studies of Human Stress.Biology of stress.

American Institute of Stress.What is stress?

MedlinePlus.Stress and your health.

American Psychological Association.Stress effects on the body.

American Psychological Association.Stress in America: our health at risk.

Plummer MP, Blaser AR, Deane AM.Stress ulceration: prevalence, pathology and association with adverse outcomes.Crit Care.2014;18(2):213. doi:10.1186/cc13780

Kalliomaki J, Jansen GB.Development of a chronic stress diagnosis.J Rehabil Med Clin Commun.2021;4:1000064. doi:10.2340/20030711-1000064

Harvard Health.Six relaxation techniques to reduce stress.

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