Table of ContentsView AllTable of ContentsAnatomyFunctionAssociated ConditionsDiagnosis

Table of ContentsView All

View All

Table of Contents

Anatomy

Function

Associated Conditions

Diagnosis

The brainstem is a stalk-like structure in thebrainthat connects a part of the brain called thecerebellumto thespinal cord.

Although small, the brainstem performs many critical functions, including controlling the heart and breathing rate, providing motor and sensory functions to the face and neck, regulating thesleep cycle, and conveying nerve signals back and forth from the brain to the rest of the body.

The article explains the anatomy and function of the brainstem and its various parts. It also describes conditions that can affect the brainstem and how they are diagnosed.

Hank Grebe / Getty Images

The brainstem is continuous wth the spinal cord

Anatomy and Parts of the Brainstem

The brainstem is the lowest part of the brain located towards the back of the neck. It is a stem-shaped structure roughly 3 inches in length extending from the middle of the brain to the spinal cord.

The brainstem receives blood supply from several arteries, including the vertebral arteries, basilar artery, and pontine arteries.

Parts of the Brainstem

The brainstem is composed of three main parts, each of which has specific functions.Each section serves as a nerve gateway, relaying motor and/or sensory information to and from different parts of the body.

The sections of the brainstem include the following:

What Does the Brainstem Do?

Locomotion and Coordination

All information relayed to and from the cerebellum must pass through the brainstem. The cerebellum, also known as the “little brain,” is responsible for coordinating movement, balance, andproprioception(the awareness of your body in space).

Motor and Sensory Function of the Head and Neck

The brainstem is where 10 of the 12 pairs ofcranial nervesoriginate. These nerves relay signals to and from the head and neck, enabling smell, vision, taste, swallowing, facial sensations, and the movement of the head, face, shoulder, eye, and tongue

The cranial nerves in the brainstem are distributed as follows:

Consciousness

Autonomic Functions

Reticular Activating System and Your Sleep

What Conditions Can Affect the Brainstem?

Several conditions can directly or indirectly affect the brainstem. Because the brainstem is responsible for many key functions, the list of possible symptoms is extensive, ranging from uncontrollable eye movements andvertigo(spinning sensations) to one-sided facial paralysis and loss of muscle control.

These are some of the conditions known to affect the brainstem:

Causes of Vertigo and How It Is Treated

Diagnosing Brainstem Problems

If you have symptoms of a brainstem problem, seek prompt medical attention. Your healthcare provider will take a careful medical history and perform a physical exam, including an in-office evaluation known as aneurological exam.

Eye movements are a key focus of the exam as brainstem diseases can often causediplopia(double vision),nystagmus(jumpy eye movements), ormyokymia(eyelid twitching).

Based on your history and physical, your medical provider may order tests to further evaluate your condition, including:

Summary

The brainstem is a roughly 3-inch structure in the brain that connects the cerebellum to the spinal cord. It is composed of three sections called the midbrain, pons, and medulla oblongata that regulate numerous functions in the body, including movement, coordination, balance, taste, smell, facial expression, reflexes, heart rate, breathing rate, blood pressure, and the sleep-wake cycle.

Conditions adversely affecting the brainstem include stroke, aneurysm, multiple sclerosis, brain tumors, Parkinson’s disease, Huntington’s disease, and increased intracranial pressure.

16 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

Sciacca S, Lynch J, Davagnanam I, Barker R.Midbrain, pons, and medulla: anatomy and syndromes.Radiographics.2019 Jul-Aug;39(4):1110-1125. doi:10.1148/rg.2019180126

Takakusaki K, Chiba R, Nozu T, Okumura T.Brainstem control of locomotion and muscle tone with special reference to the role of the mesopontine tegmentum and medullary reticulospinal system.J Neural Transm (Vienna). 2016;123(7):695–729. doi:10.1007/s00702-015-1475-4

Damodaran O, Rizk E, Rodriguez J, Lee G.Cranial nerve assessment: a concise guide to clinical examination.Clin Anat. 2014;27(1):25-30. doi:10.1002/ca.22336

Benghanem S, Mazeraud A, Azabou E, et al.Brainstem dysfunction in critically ill patients.Crit Care.2020;24:5. doi:10.1186/s13054-019-2718-9

American Heart Association.Brain stem stroke.

Geraldes R, Juryńczyk M, dos Passos GR, et al.The role of pontine lesion location in differentiating multiple sclerosis from vascular risk factor-related small vessel disease.Mult Scler. 2021;27(6):968-972. doi:10.1177%2F1352458520943777

Hawryluk GWJ, Citerio G, Hutchinson P, et al.Intracranial pressure: current perspectives on physiology and monitoring.Intensive Care Med. 2022;48(10):1471–81. doi:10.1007/s00134-022-06786-y

Basile GA, Quartu M, Bertino S, Serra MP, Boi M, Bramanti A, Anastasi GP, Milardi D, Cacciola A.Red nucleus structure and function: from anatomy to clinical neurosciences.Brain Struct Funct.2020 Nov 12. doi: 10.1007/s00429-020-02171-x

Silva MA, Chen S, Starke RM.Unruptured cerebral aneurysm risk stratification: background, current research, and future directions in aneurysm assessment.Surg Neurol Int. 2022;13:182. doi:10.25259/SNI_1112_2021

American Association of Neurological Surgeons.Brain tumors.

Powers WJ, Rabinstein AA, Ackerson T, et al.2018 Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American Stroke Association.Stroke. 2018 Mar;49(3):e46-e110. doi: 10.1161/STR.0000000000000158

Moodley A.Basic clinical examination of a patient with neuro-ophthalmology symptoms.Community Eye Health.2016;29(96):66–67.

Bouhrara M, Cortina LE, Rejimon AC, Khattar N, Bergeron C, Bergeron J, Melvin D, Zukley L, Spencer RG.Quantitative age-dependent differences in human brainstem myelination assessed using high-resolution magnetic resonance mapping.Neuroimage. 2020 Feb 1;206:116307. doi:10.1016/j.neuroimage.2019.116307

Mount Sinai.Cerebral angiogram.

Multiple Sclerosis Trust.Evoked potentials.

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