Table of ContentsView AllTable of ContentsAnatomyFunctionClinical Significance
Table of ContentsView All
View All
Table of Contents
Anatomy
Function
Clinical Significance
The superior mesenteric vein (SMV) is a large blood vessel in the abdomen. Its function is to drain blood from the small intestine as well as the first sections of the large intestine and other digestive organs. This large vein receives blood from several other veins (tributaries) in the digestive tract.
It lies to the right of the superior mesenteric artery. Nutrients absorbed from the small intestine are carried in the blood and through the SMV to thehepatic portal veinand then into the liver. Once in the liver, the nutrients can be dispersed throughout the body.
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Veins are the blood vessels that carry blood from various parts of the body and toward the heart. This is different fromarteries, which carry blood away from the heart and back toward the organs and structures of the body.
Location
The SMV is located on the right anatomical side of the abdomen and is part of the hepatic portal venous system. The superior mesenteric artery, which carries blood into thedigestive system, is on the left side of the abdomen.
The SMV joins with the splenic vein and becomes the hepatic portal vein. It is the hepatic portal vein that carries the blood to the liver.The SMV receives blood coming from several parts of the digestive tract. This includes veins coming from the small intestine, which is organized into three sections (duodenum, jejunum, and ileum).
Other veins that feed into the SMV come from sections of the large intestine which include the cecum, ascending colon, and transverse colon. Still other contributing veins come from the stomach and thepancreas.
These veins include:
The gastrocolic trunk also joins, which includes:
Anatomical Variations
In some people, the SMV may have one main trunk. In others, it may be split into two.
A midgut malrotation is a congenital condition (one that a person is born with). It often does not cause any symptoms, and it’s unknown how often it occurs. However, when there are symptoms, the condition is usually found in infants and children under the age of 5. Being diagnosed as an adult is rare.
In some cases, other congenital conditions occur along with a midgut malrotation, such as heart disease and abdominal wall defects. Surgery might be done to correct any complications such as a bowel obstruction or a twisted bowel.
There are some differences in how the tributary veins connect to the SMV. These variations can be diverse and complex.
For instance, about 50% of people don’t have a right colic vein, and a little less than half of those who do, drain into a different branch. The right gastroepiploic vein and colonic drainage veins may also drain into either the main trunk or into a different branch.
Because of these variations, it is important for surgeons to know the patient’s abdominal vein structure before surgery is done on the digestive tract. ACT angiographyscan or another test may be done to look for these differences. Understanding any variations may help in avoiding certain surgical complications.
The purpose of the SMV is to transport blood from the digestive tract to the liver. The blood comes from the small intestine, large intestine,appendix,stomach, and pancreas. The many tributary veins bring blood from all of these parts of the digestive tract to the SMV, which feeds into the hepatic portal vein, bringing the blood to the liver.
Blood coming from the midgut contains vitamins and nutrients from the food that is digested there. In the liver, the nutrients are processed into a form that the body can use. The liver stores these nutrients and parses them out when the body has a need.
Some conditions can affect the SMV. In most cases, they are uncommon or rare.
Pylephlebitis
Pylephlebitis is an uncommon condition that can follow significant infection in the abdomen, leading to clots and infection of the vein. Before the era of antibiotics, the condition was uniformly lethal. Now, it carries a mortality of up to 30%.When the SMV is affected, it is called a portomesenteric venous thrombosis.
Conditions that might lead to the development of pylephlebitis include diverticulitis, acute appendicitis, inflammatory bowel disease, pancreatitis, and gastroenteritis. Symptoms can include fever, abdominal pain, liver dysfunction, and a bacterial infection in the blood. Pylephlebitis is often treated with antibiotics.
In some cases, the lack of blood flow to the small intestine leads to complications such as the death of cells there (necrosis) or an inflammation of the abdominal wall (peritonitis). In these instances, a bowel resection, where a part of the bowel is removed, may be needed.
Isolated Superior Mesenteric Venous Thrombosis
Isolated superior mesenteric venous thrombosis (SMVT) is when ablood clotforms in the SMV. It is a rare condition.
SMVT can occur as a result of cancer,peritonitis, increased blood clotting (hypercoagulable state), protein C deficiency,polycythemia vera, recent abdominal surgery, high blood pressure in the portal vein (portal hypertension), orsepsis.
Symptoms can include fever, nausea, blood in the stool, abdominal distention or pain, and vomiting blood. This condition is most often diagnosed with aCT scan. Treatment could include antibiotics, anticoagulants, surgery to remove the clot or to place drugs to dissolve the clot, or a small intestine resection.
Injury
Patients might present with severe blood loss causing hemorrhagic shock, hyperthermia, increased acidity in the blood (acidosis), and lack of blood clotting (coagulopathy). A CT scan may be done to assess the injury, but often, exploratory surgery is done to repair the damage.
In other cases, when a patient isn’t stable enough to undergo a lengthy repair surgery, the SMV may be clamped (ligation).
8 Sources
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Broussard A, Wehrle CJ, Samra NS.Anatomy, abdomen and pelvis, superior mesenteric vein. StatPearls.
Alani M, Rentea RM.Midgut malrotation. StatPearls.
Alsabilah J, Kim WR, Kim NK.Vascular structures of the right colon: Incidence and variations with their clinical implications.Scand J Surg. 2017;106:107-115. doi:10.1177/1457496916650999
Murono K, Kawai K, Ishihara S, et al.Evaluation of the vascular anatomy of the right-sided colon using three-dimensional computed tomography angiography: a single-center study of 536 patients and a review of the literature.Int J Colorectal Dis. 2016;31:1633-1638. doi:10.1007/s00384-016-2627-1.
Wong K, Weisman DS, Patrice KA.Pylephlebitis: a rare complication of an intra-abdominal infection.J Community Hosp Intern Med Perspect. 2013;3(2):10.3402/jchimp.v3i2.20732. doi:10.3402/jchimp.v3i2.20732
Choudhry AJ, Baghdadi YM, Amr MA, Alzghari MJ, Jenkins DH, Zielinski MD.Pylephlebitis: a Review of 95 Cases.J Gastrointest Surg. 2016;20:656-661. doi:10.1007/s11605-015-2875-3.
Cho JW, Choi JJ, Um E, et al.Clinical manifestations of superior mesenteric venous thrombosis in the era of computed tomography.Vasc Specialist Int. 2018;34:83-87. doi:10.5758/vsi.2018.34.4.83.
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