Table of ContentsView AllTable of ContentsFood SourcesResearchSafetyFrequently Asked Questions
Table of ContentsView All
View All
Table of Contents
Food Sources
Research
Safety
Frequently Asked Questions
Lactiplantibacillus plantarum(L. plantarum,formerly calledLactobacillus plantarum)is aprobiotic bacteriumthat may help to reduce inflammation, manage blood sugar in people with diabetes, reduce depression, and improve sleep quality.
L. plantarumis present in fermented foods and beverages, but researchers have also observed this probiotic in the body’smucous membranes, saliva, and digestive tract (gut).L. plantarumis also found in over-the-counterprobiotic supplements. Potential benefits ofL. plantarumhave been studied in clinical trials. But research results are inconsistent so studies are ongoing.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
Westend61 / Getty Images
Fermented Foods and Beverages
A vibrant history offermentedfoods and beverages exists from around the globe.L. plantarumcan be found in fermented foods and beverages such as the following:
There are many morefermentedfruits and vegetables than what is listed here.
Finding new recipes, learning more about the rich cultures they come from, and taste-testing to see which ones you like can be a fun way to continue to support your health.
The Research
There is significant interest in themicrobiome(all the microorganisms living in your body). Researchers have drawn connections between the gut microbiome and nervous system health.
Studies have found links in how changing your body’s microbe balance can influence your health.L. plantarumimpacts the microbiome and beyond. It has been studied for the following conditions:
As with any natural remedy or dietary supplement,L. plantarumshould not be used as a substitute for standard care. More studies are needed to confirm these results.
Speak with your healthcare provider if you have questions about your health.
Side Effects and Safety Concerns
Some individuals have experienced side effects fromL. plantarum,including gas and bloating.
In the following cases, avoid takingL. plantarumuntil discussing it further with your healthcare provider:
There has also been interest in how the gut microbiome impacts the body’s use of certain medications and how medications impact the microbiome.
Antibiotics, while helpful, can reduce both bad and good microbes in the body.
However, a review suggested following nonantibiotic medicines also impact levels ofLactobacillusspecies in the body:
Some supplements risk being contaminated. Seek products that mention “current good manufacturing practices” (CGMP) on the label.
Summary
Research suggestsL. plantarummay offer some health benefits. However, more, extensive clinical trials are needed to confirm results. To boost your intake ofL. plantarumfrom foods, look into fermented foods such as sauerkraut and kimchi.
If you’re considering takingL. plantarumin supplement form, speak with your healthcare provider to ensure it’s the right option.
Yes.Lactiplantibacillus plantarumis one of the most varied species of lactic acid bacteria. It was formerly known asLactobacillus plantarum.
Some individuals have experienced side effects like gas and bloating.
Before making dietary or movement changes, check in with your healthcare provider if you have underlying health conditions likekidney conditionsordiabetes. In this case, you may need further, tailored advice about the balance of your diet. Seeking guidance from aregistered dietitian nutritionist (RD or RDN)can be especially helpful.
Research demonstrated specific strains ofL. plantarumbenefited some symptoms ofirritable bowel syndrome (IBS)but not all. One study suggested benefits for bowel frequency and stool consistency (Bristol score) using 3.52 billion CFU of the CCFM1143 strain daily.Another study used 10 billion colony-forming units (cfu) of the 299v strain for four weeks with significant benefit.However, another using the 299v strain didnothelp IBS symptoms.
23 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Arasu MV, Al-Dhabi NA, Ilavenil S, et al.In vitro importance of probiotic Lactobacillus plantarum related to medical field.Saudi J Biol Sci. 2016;23(1):S6-S10. doi:10.1016/j.sjbs.2015.09.022Silva-Bea S, Francisco-Tomé M, Cabrera-Alvargonzález JJ, et al.In vivo monitoring of Lactiplantibacillus plantarum in the nasal and vaginal mucosa using infrared fluorescence.Appl Microbiol Biotechnol. 2022;106(18):6239-6251. doi:10.1007/s00253-022-12121-8Behera SS, Ray RC, Zdolec N.Lactobacillus plantarumwith functional properties: An approach to increase safety and shelf-life of fermented foods.Biomed Res Int. 2018;2018:9361614. doi:10.1155/2018/9361614Mayer EA, Nance K, Chen S.The gut-brain axis.Annu Rev Med. 2022;73:439-453. doi:10.1146/annurev-med-042320-014032Osadchiy V, Martin CR, Mayer EA.The gut-brain axis and the microbiome: mechanisms and clinical implications.Clin Gastroenterol Hepatol. 2019;17(2):322-332. doi:10.1016/j.cgh.2018.10.002Lew LC, Hor YY, Yusoff NAA, et al.Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clin Nutr. 2019;38(5):2053-2064. doi:10.1016/j.clnu.2018.09.010Chong HX, Yusoff NAA, Hor YY, et al.Lactobacillus plantarumDR7 alleviates stress and anxiety in adults: A randomised, double-blind, placebo-controlled study.Benef Microbes. 2019;10(4):355-373. doi:10.3920/BM2018.0135Liu YW, Liong MT, Chung YE, et al.Effects ofLactobacillus plantarumPS128 on children with autism spectrum disorder in Taiwan: A randomized, double-blind, placebo-controlled trial.Nutrients. 2019;11(4):820. doi:10.3390/nu11040820Han Y, Kim B, Ban J, et al.A randomized trial of CJLP133 for the treatment of atopic dermatitis.Pediatr Allergy Immunol. 2012;23(7):667-73. doi:10.1111/pai.12010Oh MR, Jang HY, Lee SY, et al.Lactobacillus plantarum hac01 supplementation improves glycemic control in prediabetic subjects: a randomized, double-blind, placebo-controlled trial.Nutrients. 2021;13(7):2337. doi:10.3390/nu13072337Toshimitsu T, Gotou A, Sashihara T, et al.Effects of 12-week ingestion of yogurt containing Lactobacillus plantarum Oll2712 on glucose metabolism and chronic inflammation in prediabetic adults: a randomized placebo-controlled trial.Nutrients. 2020;12(2):374. doi:10.3390/nu12020374Ho YT, Tsai YC, Kuo TBJ, Yang CCH.Effects of Lactobacillus plantarum PS128 on depressive symptoms and sleep quality in self-reported insomniacs: a randomized, double-blind, placebo-controlled pilot trial.Nutrients. 2021;13(8):2820. doi:10.3390/nu13082820Lewis-Mikhael AM, Davoodvandi A, Jafarnejad S.Effect of Lactobacillus plantarum containing probiotics on blood pressure: A systematic review and meta-analysis.Pharmacol Res. 2020;153:104663. doi:10.1016/j.phrs.2020.104663Zhao W, Peng C, Sakandar HA, et al. Meta-analysis:Randomized trials of Lactobacillus plantarum on immune regulation over the last decades.Front Immunol. 2021;12:643420. doi:10.3389/fimmu.2021.643420Huang W, Lee M, Lee C, et al.Effect of Lactobacillus plantarum TWK10 on exercise physiological adaptation, performance, and body composition in healthy humans.Nutrients. 2019;11(11):2836-. doi:10.3390/nu11112836Krag A, Munkholm P, Israelsen H, et al.Profermin is efficacious in patients with active ulcerative colitis–a randomized controlled trial.Inflamm Bowel Dis. 2013;19(12):2584-2592. doi:10.1097/01.MIB.0000437046.26036.dbYang B, Yue Y, Chen Y, et al.Lactobacillus plantarum CCFM1143 alleviates chronic diarrhea via inflammation regulation and gut microbiota modulation: A double-blind, randomized, placebo-controlled study.Front Immunol. 2021;12:746585. doi:10.3389/fimmu.2021.746585Ducrotté, P.Clinical trial: lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.WJG. 2012;18(30):4012-. doi:10.3748/wjg.v18.i30.4012Stevenson C, Blaauw R, Fredericks E, et al.Randomized clinical trial: effect of Lactobacillus plantarum 299 v on symptoms of irritable bowel syndrome.Nutrition. 2014;30(10):1151-1157. doi:10.1016/j.nut.2014.02.010National Center for Complementary and Integrative Health.Probiotics: what you need to know.Rahman A, Alqaisi S, Nath J.A case of Lactobacillus casei endocarditis associated with probiotic intake in an immunocompromised patient.Cureus. 2023;15(4):e38049. doi:10.7759/cureus.38049Weersma RK, Zhernakova A, Fu J.Interaction between drugs and the gut microbiome.Gut. 2020;69(8):1510-1519. doi:10.1136/gutjnl-2019-320204Yilmaz B, Bangar SP, Echegaray N, et al.The impacts of Lactiplantibacillus plantarum on the functional properties of fermented foods: A review of current knowledge.Microorganisms. 2022;10(4):826. doi:10.3390/microorganisms10040826Additional ReadingLew L, Hor Y, Yusoff NAA, et al.Probiotic lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clinical Nutrition. 2019;38(5):2053-2064.
23 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Arasu MV, Al-Dhabi NA, Ilavenil S, et al.In vitro importance of probiotic Lactobacillus plantarum related to medical field.Saudi J Biol Sci. 2016;23(1):S6-S10. doi:10.1016/j.sjbs.2015.09.022Silva-Bea S, Francisco-Tomé M, Cabrera-Alvargonzález JJ, et al.In vivo monitoring of Lactiplantibacillus plantarum in the nasal and vaginal mucosa using infrared fluorescence.Appl Microbiol Biotechnol. 2022;106(18):6239-6251. doi:10.1007/s00253-022-12121-8Behera SS, Ray RC, Zdolec N.Lactobacillus plantarumwith functional properties: An approach to increase safety and shelf-life of fermented foods.Biomed Res Int. 2018;2018:9361614. doi:10.1155/2018/9361614Mayer EA, Nance K, Chen S.The gut-brain axis.Annu Rev Med. 2022;73:439-453. doi:10.1146/annurev-med-042320-014032Osadchiy V, Martin CR, Mayer EA.The gut-brain axis and the microbiome: mechanisms and clinical implications.Clin Gastroenterol Hepatol. 2019;17(2):322-332. doi:10.1016/j.cgh.2018.10.002Lew LC, Hor YY, Yusoff NAA, et al.Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clin Nutr. 2019;38(5):2053-2064. doi:10.1016/j.clnu.2018.09.010Chong HX, Yusoff NAA, Hor YY, et al.Lactobacillus plantarumDR7 alleviates stress and anxiety in adults: A randomised, double-blind, placebo-controlled study.Benef Microbes. 2019;10(4):355-373. doi:10.3920/BM2018.0135Liu YW, Liong MT, Chung YE, et al.Effects ofLactobacillus plantarumPS128 on children with autism spectrum disorder in Taiwan: A randomized, double-blind, placebo-controlled trial.Nutrients. 2019;11(4):820. doi:10.3390/nu11040820Han Y, Kim B, Ban J, et al.A randomized trial of CJLP133 for the treatment of atopic dermatitis.Pediatr Allergy Immunol. 2012;23(7):667-73. doi:10.1111/pai.12010Oh MR, Jang HY, Lee SY, et al.Lactobacillus plantarum hac01 supplementation improves glycemic control in prediabetic subjects: a randomized, double-blind, placebo-controlled trial.Nutrients. 2021;13(7):2337. doi:10.3390/nu13072337Toshimitsu T, Gotou A, Sashihara T, et al.Effects of 12-week ingestion of yogurt containing Lactobacillus plantarum Oll2712 on glucose metabolism and chronic inflammation in prediabetic adults: a randomized placebo-controlled trial.Nutrients. 2020;12(2):374. doi:10.3390/nu12020374Ho YT, Tsai YC, Kuo TBJ, Yang CCH.Effects of Lactobacillus plantarum PS128 on depressive symptoms and sleep quality in self-reported insomniacs: a randomized, double-blind, placebo-controlled pilot trial.Nutrients. 2021;13(8):2820. doi:10.3390/nu13082820Lewis-Mikhael AM, Davoodvandi A, Jafarnejad S.Effect of Lactobacillus plantarum containing probiotics on blood pressure: A systematic review and meta-analysis.Pharmacol Res. 2020;153:104663. doi:10.1016/j.phrs.2020.104663Zhao W, Peng C, Sakandar HA, et al. Meta-analysis:Randomized trials of Lactobacillus plantarum on immune regulation over the last decades.Front Immunol. 2021;12:643420. doi:10.3389/fimmu.2021.643420Huang W, Lee M, Lee C, et al.Effect of Lactobacillus plantarum TWK10 on exercise physiological adaptation, performance, and body composition in healthy humans.Nutrients. 2019;11(11):2836-. doi:10.3390/nu11112836Krag A, Munkholm P, Israelsen H, et al.Profermin is efficacious in patients with active ulcerative colitis–a randomized controlled trial.Inflamm Bowel Dis. 2013;19(12):2584-2592. doi:10.1097/01.MIB.0000437046.26036.dbYang B, Yue Y, Chen Y, et al.Lactobacillus plantarum CCFM1143 alleviates chronic diarrhea via inflammation regulation and gut microbiota modulation: A double-blind, randomized, placebo-controlled study.Front Immunol. 2021;12:746585. doi:10.3389/fimmu.2021.746585Ducrotté, P.Clinical trial: lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.WJG. 2012;18(30):4012-. doi:10.3748/wjg.v18.i30.4012Stevenson C, Blaauw R, Fredericks E, et al.Randomized clinical trial: effect of Lactobacillus plantarum 299 v on symptoms of irritable bowel syndrome.Nutrition. 2014;30(10):1151-1157. doi:10.1016/j.nut.2014.02.010National Center for Complementary and Integrative Health.Probiotics: what you need to know.Rahman A, Alqaisi S, Nath J.A case of Lactobacillus casei endocarditis associated with probiotic intake in an immunocompromised patient.Cureus. 2023;15(4):e38049. doi:10.7759/cureus.38049Weersma RK, Zhernakova A, Fu J.Interaction between drugs and the gut microbiome.Gut. 2020;69(8):1510-1519. doi:10.1136/gutjnl-2019-320204Yilmaz B, Bangar SP, Echegaray N, et al.The impacts of Lactiplantibacillus plantarum on the functional properties of fermented foods: A review of current knowledge.Microorganisms. 2022;10(4):826. doi:10.3390/microorganisms10040826Additional ReadingLew L, Hor Y, Yusoff NAA, et al.Probiotic lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clinical Nutrition. 2019;38(5):2053-2064.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Arasu MV, Al-Dhabi NA, Ilavenil S, et al.In vitro importance of probiotic Lactobacillus plantarum related to medical field.Saudi J Biol Sci. 2016;23(1):S6-S10. doi:10.1016/j.sjbs.2015.09.022Silva-Bea S, Francisco-Tomé M, Cabrera-Alvargonzález JJ, et al.In vivo monitoring of Lactiplantibacillus plantarum in the nasal and vaginal mucosa using infrared fluorescence.Appl Microbiol Biotechnol. 2022;106(18):6239-6251. doi:10.1007/s00253-022-12121-8Behera SS, Ray RC, Zdolec N.Lactobacillus plantarumwith functional properties: An approach to increase safety and shelf-life of fermented foods.Biomed Res Int. 2018;2018:9361614. doi:10.1155/2018/9361614Mayer EA, Nance K, Chen S.The gut-brain axis.Annu Rev Med. 2022;73:439-453. doi:10.1146/annurev-med-042320-014032Osadchiy V, Martin CR, Mayer EA.The gut-brain axis and the microbiome: mechanisms and clinical implications.Clin Gastroenterol Hepatol. 2019;17(2):322-332. doi:10.1016/j.cgh.2018.10.002Lew LC, Hor YY, Yusoff NAA, et al.Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clin Nutr. 2019;38(5):2053-2064. doi:10.1016/j.clnu.2018.09.010Chong HX, Yusoff NAA, Hor YY, et al.Lactobacillus plantarumDR7 alleviates stress and anxiety in adults: A randomised, double-blind, placebo-controlled study.Benef Microbes. 2019;10(4):355-373. doi:10.3920/BM2018.0135Liu YW, Liong MT, Chung YE, et al.Effects ofLactobacillus plantarumPS128 on children with autism spectrum disorder in Taiwan: A randomized, double-blind, placebo-controlled trial.Nutrients. 2019;11(4):820. doi:10.3390/nu11040820Han Y, Kim B, Ban J, et al.A randomized trial of CJLP133 for the treatment of atopic dermatitis.Pediatr Allergy Immunol. 2012;23(7):667-73. doi:10.1111/pai.12010Oh MR, Jang HY, Lee SY, et al.Lactobacillus plantarum hac01 supplementation improves glycemic control in prediabetic subjects: a randomized, double-blind, placebo-controlled trial.Nutrients. 2021;13(7):2337. doi:10.3390/nu13072337Toshimitsu T, Gotou A, Sashihara T, et al.Effects of 12-week ingestion of yogurt containing Lactobacillus plantarum Oll2712 on glucose metabolism and chronic inflammation in prediabetic adults: a randomized placebo-controlled trial.Nutrients. 2020;12(2):374. doi:10.3390/nu12020374Ho YT, Tsai YC, Kuo TBJ, Yang CCH.Effects of Lactobacillus plantarum PS128 on depressive symptoms and sleep quality in self-reported insomniacs: a randomized, double-blind, placebo-controlled pilot trial.Nutrients. 2021;13(8):2820. doi:10.3390/nu13082820Lewis-Mikhael AM, Davoodvandi A, Jafarnejad S.Effect of Lactobacillus plantarum containing probiotics on blood pressure: A systematic review and meta-analysis.Pharmacol Res. 2020;153:104663. doi:10.1016/j.phrs.2020.104663Zhao W, Peng C, Sakandar HA, et al. Meta-analysis:Randomized trials of Lactobacillus plantarum on immune regulation over the last decades.Front Immunol. 2021;12:643420. doi:10.3389/fimmu.2021.643420Huang W, Lee M, Lee C, et al.Effect of Lactobacillus plantarum TWK10 on exercise physiological adaptation, performance, and body composition in healthy humans.Nutrients. 2019;11(11):2836-. doi:10.3390/nu11112836Krag A, Munkholm P, Israelsen H, et al.Profermin is efficacious in patients with active ulcerative colitis–a randomized controlled trial.Inflamm Bowel Dis. 2013;19(12):2584-2592. doi:10.1097/01.MIB.0000437046.26036.dbYang B, Yue Y, Chen Y, et al.Lactobacillus plantarum CCFM1143 alleviates chronic diarrhea via inflammation regulation and gut microbiota modulation: A double-blind, randomized, placebo-controlled study.Front Immunol. 2021;12:746585. doi:10.3389/fimmu.2021.746585Ducrotté, P.Clinical trial: lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.WJG. 2012;18(30):4012-. doi:10.3748/wjg.v18.i30.4012Stevenson C, Blaauw R, Fredericks E, et al.Randomized clinical trial: effect of Lactobacillus plantarum 299 v on symptoms of irritable bowel syndrome.Nutrition. 2014;30(10):1151-1157. doi:10.1016/j.nut.2014.02.010National Center for Complementary and Integrative Health.Probiotics: what you need to know.Rahman A, Alqaisi S, Nath J.A case of Lactobacillus casei endocarditis associated with probiotic intake in an immunocompromised patient.Cureus. 2023;15(4):e38049. doi:10.7759/cureus.38049Weersma RK, Zhernakova A, Fu J.Interaction between drugs and the gut microbiome.Gut. 2020;69(8):1510-1519. doi:10.1136/gutjnl-2019-320204Yilmaz B, Bangar SP, Echegaray N, et al.The impacts of Lactiplantibacillus plantarum on the functional properties of fermented foods: A review of current knowledge.Microorganisms. 2022;10(4):826. doi:10.3390/microorganisms10040826
Arasu MV, Al-Dhabi NA, Ilavenil S, et al.In vitro importance of probiotic Lactobacillus plantarum related to medical field.Saudi J Biol Sci. 2016;23(1):S6-S10. doi:10.1016/j.sjbs.2015.09.022
Silva-Bea S, Francisco-Tomé M, Cabrera-Alvargonzález JJ, et al.In vivo monitoring of Lactiplantibacillus plantarum in the nasal and vaginal mucosa using infrared fluorescence.Appl Microbiol Biotechnol. 2022;106(18):6239-6251. doi:10.1007/s00253-022-12121-8
Behera SS, Ray RC, Zdolec N.Lactobacillus plantarumwith functional properties: An approach to increase safety and shelf-life of fermented foods.Biomed Res Int. 2018;2018:9361614. doi:10.1155/2018/9361614
Mayer EA, Nance K, Chen S.The gut-brain axis.Annu Rev Med. 2022;73:439-453. doi:10.1146/annurev-med-042320-014032
Osadchiy V, Martin CR, Mayer EA.The gut-brain axis and the microbiome: mechanisms and clinical implications.Clin Gastroenterol Hepatol. 2019;17(2):322-332. doi:10.1016/j.cgh.2018.10.002
Lew LC, Hor YY, Yusoff NAA, et al.Probiotic Lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clin Nutr. 2019;38(5):2053-2064. doi:10.1016/j.clnu.2018.09.010
Chong HX, Yusoff NAA, Hor YY, et al.Lactobacillus plantarumDR7 alleviates stress and anxiety in adults: A randomised, double-blind, placebo-controlled study.Benef Microbes. 2019;10(4):355-373. doi:10.3920/BM2018.0135
Liu YW, Liong MT, Chung YE, et al.Effects ofLactobacillus plantarumPS128 on children with autism spectrum disorder in Taiwan: A randomized, double-blind, placebo-controlled trial.Nutrients. 2019;11(4):820. doi:10.3390/nu11040820
Han Y, Kim B, Ban J, et al.A randomized trial of CJLP133 for the treatment of atopic dermatitis.Pediatr Allergy Immunol. 2012;23(7):667-73. doi:10.1111/pai.12010
Oh MR, Jang HY, Lee SY, et al.Lactobacillus plantarum hac01 supplementation improves glycemic control in prediabetic subjects: a randomized, double-blind, placebo-controlled trial.Nutrients. 2021;13(7):2337. doi:10.3390/nu13072337
Toshimitsu T, Gotou A, Sashihara T, et al.Effects of 12-week ingestion of yogurt containing Lactobacillus plantarum Oll2712 on glucose metabolism and chronic inflammation in prediabetic adults: a randomized placebo-controlled trial.Nutrients. 2020;12(2):374. doi:10.3390/nu12020374
Ho YT, Tsai YC, Kuo TBJ, Yang CCH.Effects of Lactobacillus plantarum PS128 on depressive symptoms and sleep quality in self-reported insomniacs: a randomized, double-blind, placebo-controlled pilot trial.Nutrients. 2021;13(8):2820. doi:10.3390/nu13082820
Lewis-Mikhael AM, Davoodvandi A, Jafarnejad S.Effect of Lactobacillus plantarum containing probiotics on blood pressure: A systematic review and meta-analysis.Pharmacol Res. 2020;153:104663. doi:10.1016/j.phrs.2020.104663
Zhao W, Peng C, Sakandar HA, et al. Meta-analysis:Randomized trials of Lactobacillus plantarum on immune regulation over the last decades.Front Immunol. 2021;12:643420. doi:10.3389/fimmu.2021.643420
Huang W, Lee M, Lee C, et al.Effect of Lactobacillus plantarum TWK10 on exercise physiological adaptation, performance, and body composition in healthy humans.Nutrients. 2019;11(11):2836-. doi:10.3390/nu11112836
Krag A, Munkholm P, Israelsen H, et al.Profermin is efficacious in patients with active ulcerative colitis–a randomized controlled trial.Inflamm Bowel Dis. 2013;19(12):2584-2592. doi:10.1097/01.MIB.0000437046.26036.db
Yang B, Yue Y, Chen Y, et al.Lactobacillus plantarum CCFM1143 alleviates chronic diarrhea via inflammation regulation and gut microbiota modulation: A double-blind, randomized, placebo-controlled study.Front Immunol. 2021;12:746585. doi:10.3389/fimmu.2021.746585
Ducrotté, P.Clinical trial: lactobacillus plantarum 299v (DSM 9843) improves symptoms of irritable bowel syndrome.WJG. 2012;18(30):4012-. doi:10.3748/wjg.v18.i30.4012
Stevenson C, Blaauw R, Fredericks E, et al.Randomized clinical trial: effect of Lactobacillus plantarum 299 v on symptoms of irritable bowel syndrome.Nutrition. 2014;30(10):1151-1157. doi:10.1016/j.nut.2014.02.010
National Center for Complementary and Integrative Health.Probiotics: what you need to know.
Rahman A, Alqaisi S, Nath J.A case of Lactobacillus casei endocarditis associated with probiotic intake in an immunocompromised patient.Cureus. 2023;15(4):e38049. doi:10.7759/cureus.38049
Weersma RK, Zhernakova A, Fu J.Interaction between drugs and the gut microbiome.Gut. 2020;69(8):1510-1519. doi:10.1136/gutjnl-2019-320204
Yilmaz B, Bangar SP, Echegaray N, et al.The impacts of Lactiplantibacillus plantarum on the functional properties of fermented foods: A review of current knowledge.Microorganisms. 2022;10(4):826. doi:10.3390/microorganisms10040826
Lew L, Hor Y, Yusoff NAA, et al.Probiotic lactobacillus plantarum P8 alleviated stress and anxiety while enhancing memory and cognition in stressed adults: A randomised, double-blind, placebo-controlled study.Clinical Nutrition. 2019;38(5):2053-2064.
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