Table of ContentsView AllTable of ContentsHow It WorksIngredientsWarningsDosing InstructionsFrequently Asked Questions
Table of ContentsView All
View All
Table of Contents
How It Works
Ingredients
Warnings
Dosing Instructions
Frequently Asked Questions
Tylenol 8 HR Arthritis Pain is an oral analgesic drug that helps control mild arthritis pain. It contains the active ingredient acetaminophen, a non-opioid painkiller, and is available over the counter for use in adults 18 and over.
For people with arthritis,analgesicslike acetaminophen can significantly reduce pain and improve daily life. At the same time, using acetaminophen can increase your risk of liver damage and should not be combined with any other medication—prescription or over-the-counter (OTC)—containing acetaminophen.
This article discusses how Tylenol Arthritis works along with what the medication contains. It also covers the possible side effects that can come with taking Tylenol Arthritis and dosage information you should know before using it.
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How Tylenol Arthritis Works
Tylenol Arthritis contains two layers—one that releases quickly for fast relief and one that releases slowly to providelasting relief of up to eight hours. For these layers to work properly, you must swallow the caplets whole with water.
There is a total of 650 milligrams (mg) of acetaminophen in each tablet. Regular Strength and Extra Strength Tylenol do not have two layers and contain less acetaminophen per caplet, 325 mg and 500 mg respectively.
Acetaminophen is an analgesic, meaning it relieves pain. Acetaminophen is not an anti-inflammatory, so it does not ease swelling. For this reason, Tylenol Arthritis is best for osteoarthritis and not inflammatory types of arthritis such as rheumatoid, reactive, or gout.
Tylenol Arthritis can temporarily relieve other types of pain such as general aches, muscle soreness, toothache, menstrual cramps, aches due to cold and flu, and back pain. As with other acetaminophen-containing drugs, Tylenol Arthritis can also help reduce fevers.
What’s the Difference Between Acetaminophen and Ibuprofen?
Tylenol Arthritis Ingredients
The inactive ingredients in Tylenol Arthritis include:
Tylenol Arthritis Warnings
Acetaminophen-containing drugs are known to potentially cause liver damage if you take too much. Keep your limit to 3 grams per day, especially if you weigh under 150 pounds.
In addition, a 2022 study published in the journalCirculationfound a strong connection between the daily use of acetaminophen and increased blood pressure.If you have high blood pressure or are at risk, then this is something to discuss with your healthcare provider.
Taking Tylenol Arthritis according to the directions is vital:
As with any drug, some side effects are possible. It’s vital to seek help for severe side effects, but less serious ones can be treated at home. Some common, treatable side effects include:
Side effects to tell your healthcare provider about right away include:
It is essential to be very careful when taking Tylenol Arthritis. Liver damage leading to serious health effects like liver failure and death can happen over a few days.
Some signs of Tylenol Arthritis overdose may appear over time and not be easily connected to this medication. You might first experience symptoms such as nausea, vomiting, and loss of appetite.
Signs of a Tylenol OverdoseDiarrheaSwollen, painful, or tender upper abdomen or stomachNausea and vomitingNo appetiteSweatingPain or cramping in the stomach
Signs of a Tylenol Overdose
DiarrheaSwollen, painful, or tender upper abdomen or stomachNausea and vomitingNo appetiteSweatingPain or cramping in the stomach
How Tylenol Can Cause Liver Damage
How to Take Tylenol Arthritis
Adults over 18 can take two caplets of Tylenol Arthritis every eight hours with water. Swallow whole; do not crush, chew, split, cut, or dissolve caplets.
Do not take more than six capsules within 24 hours, and do not take Tylenol Arthritis with other medications containing acetaminophen (prescription or nonprescription). If you are unsure whether any other medications you are taking contain acetaminophen, ask your healthcare provider or pharmacist.
Do Not Take With Other Medications Containing AcetaminophenTo prevent overdose, do not take Tylenol Arthritis with any other medications containing acetaminophen, including certain cold medications, menstrual pain relievers, and decongestants.Look at the active ingredients list on OTC medications and check for “acetaminophen” or “APAP” listed on prescription labels.
Do Not Take With Other Medications Containing Acetaminophen
To prevent overdose, do not take Tylenol Arthritis with any other medications containing acetaminophen, including certain cold medications, menstrual pain relievers, and decongestants.Look at the active ingredients list on OTC medications and check for “acetaminophen” or “APAP” listed on prescription labels.
To prevent overdose, do not take Tylenol Arthritis with any other medications containing acetaminophen, including certain cold medications, menstrual pain relievers, and decongestants.
Look at the active ingredients list on OTC medications and check for “acetaminophen” or “APAP” listed on prescription labels.
Tylenol Arthritis can be taken every day for up to 10 days. Acetaminophen can cause liver damage if taken in large doses.Do not drink more than two alcoholic beverages a day while taking Tylenol Arthritis.
The Most Effective Tylenol For Your Symptoms
Summary
Daily use of acetaminophen can increase blood pressure and raise your risk of serious liver damage. Tylenol Arthritis should not be combined with any other medication containing acetaminophen.
Signs of Tylenol Arthritis overdose may appear gradually and not be readily linked to the medication. You might first experience symptoms such as nausea, vomiting, and loss of appetite.
Side effects encountered with daily use can range from mild (nausea, dry mouth) to severe (internal bleeding, jaundice).
Frequently Asked QuestionsRegular Tylenol contains 325 mg of acetaminophen and lasts about four to six hours. Tylenol 8-Hour Arthritis Pain contains 650 mg of acetaminophen with a unique double-layer design. The first layer dissolves quickly to release 325 mg of acetaminophen. The second layer is extended-release. Tylenol Arthritis provides relief that lasts for up to eight hours.No, Tylenol Arthritis (acetaminophen) is not a nonsteroidal anti-inflammatory drug (NSAID). Acetaminophen relieves pain and fevers, but it does not treat inflammation.
Regular Tylenol contains 325 mg of acetaminophen and lasts about four to six hours. Tylenol 8-Hour Arthritis Pain contains 650 mg of acetaminophen with a unique double-layer design. The first layer dissolves quickly to release 325 mg of acetaminophen. The second layer is extended-release. Tylenol Arthritis provides relief that lasts for up to eight hours.
No, Tylenol Arthritis (acetaminophen) is not a nonsteroidal anti-inflammatory drug (NSAID). Acetaminophen relieves pain and fevers, but it does not treat inflammation.
10 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Mitchell RA, Rathi S, Dahiya M, Zhu J, Hussaini T, Yoshida EM.Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.PLoS ONE. 2020;15(3):e0229070. doi:10.1371/journal.pone.0229070Gabay M, Tanzi M.Medications for chronic pain—nonopioid analgesics.Practical Pain Management. 2015;11(3).DailyMed.Label: TYLENOL 8 HR ARTHRITIS PAIN- acetaminophen tablet, extended release.Harvard Health Publishing.Acetamenophen Safety: Be Cautious But Not Afraid.MacIntyre I, Turtle E, Farrah T, Graham C, Dear J, Webb D.Regular acetaminophen use and blood pressure in people with hypertension: The PATH-BP trial.Circulation. 2022 Feb;145(6):416-423. doi:10.1161/CIRCULATIONAHA.121.056015Arthritis Foundation.Analgesics.Drugs.com.Acetaminophen Side Effects.U.S. Food and Drug Administration.FDA Drug Safety Communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.Acetaminophen.LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.Johnson & Johnson Consumer, Inc. - Tylenol.TYLENOL 8 HR Arthritis Pain Relief Tablets.
10 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Mitchell RA, Rathi S, Dahiya M, Zhu J, Hussaini T, Yoshida EM.Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.PLoS ONE. 2020;15(3):e0229070. doi:10.1371/journal.pone.0229070Gabay M, Tanzi M.Medications for chronic pain—nonopioid analgesics.Practical Pain Management. 2015;11(3).DailyMed.Label: TYLENOL 8 HR ARTHRITIS PAIN- acetaminophen tablet, extended release.Harvard Health Publishing.Acetamenophen Safety: Be Cautious But Not Afraid.MacIntyre I, Turtle E, Farrah T, Graham C, Dear J, Webb D.Regular acetaminophen use and blood pressure in people with hypertension: The PATH-BP trial.Circulation. 2022 Feb;145(6):416-423. doi:10.1161/CIRCULATIONAHA.121.056015Arthritis Foundation.Analgesics.Drugs.com.Acetaminophen Side Effects.U.S. Food and Drug Administration.FDA Drug Safety Communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.Acetaminophen.LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.Johnson & Johnson Consumer, Inc. - Tylenol.TYLENOL 8 HR Arthritis Pain Relief Tablets.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Mitchell RA, Rathi S, Dahiya M, Zhu J, Hussaini T, Yoshida EM.Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.PLoS ONE. 2020;15(3):e0229070. doi:10.1371/journal.pone.0229070Gabay M, Tanzi M.Medications for chronic pain—nonopioid analgesics.Practical Pain Management. 2015;11(3).DailyMed.Label: TYLENOL 8 HR ARTHRITIS PAIN- acetaminophen tablet, extended release.Harvard Health Publishing.Acetamenophen Safety: Be Cautious But Not Afraid.MacIntyre I, Turtle E, Farrah T, Graham C, Dear J, Webb D.Regular acetaminophen use and blood pressure in people with hypertension: The PATH-BP trial.Circulation. 2022 Feb;145(6):416-423. doi:10.1161/CIRCULATIONAHA.121.056015Arthritis Foundation.Analgesics.Drugs.com.Acetaminophen Side Effects.U.S. Food and Drug Administration.FDA Drug Safety Communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.Acetaminophen.LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.Johnson & Johnson Consumer, Inc. - Tylenol.TYLENOL 8 HR Arthritis Pain Relief Tablets.
Mitchell RA, Rathi S, Dahiya M, Zhu J, Hussaini T, Yoshida EM.Public awareness of acetaminophen and risks of drug induced liver injury: Results of a large outpatient clinic survey.PLoS ONE. 2020;15(3):e0229070. doi:10.1371/journal.pone.0229070
Gabay M, Tanzi M.Medications for chronic pain—nonopioid analgesics.Practical Pain Management. 2015;11(3).
DailyMed.Label: TYLENOL 8 HR ARTHRITIS PAIN- acetaminophen tablet, extended release.
Harvard Health Publishing.Acetamenophen Safety: Be Cautious But Not Afraid.
MacIntyre I, Turtle E, Farrah T, Graham C, Dear J, Webb D.Regular acetaminophen use and blood pressure in people with hypertension: The PATH-BP trial.Circulation. 2022 Feb;145(6):416-423. doi:10.1161/CIRCULATIONAHA.121.056015
Arthritis Foundation.Analgesics.
Drugs.com.Acetaminophen Side Effects.
U.S. Food and Drug Administration.FDA Drug Safety Communication: FDA warns of rare but serious skin reactions with the pain reliever/fever reducer acetaminophen.
Acetaminophen.LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012.
Johnson & Johnson Consumer, Inc. - Tylenol.TYLENOL 8 HR Arthritis Pain Relief Tablets.
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