Table of ContentsView AllTable of ContentsUnderstanding DiarrheaUsing Antidiarrheal DrugsTypes of Antidiarrheal DrugsFAQ

Table of ContentsView All

View All

Table of Contents

Understanding Diarrhea

Using Antidiarrheal Drugs

Types of Antidiarrheal Drugs

FAQ

An antidiarrheal is a drug that is used to slow down or stopdiarrhea(loose stools). Antidiarrheals are used for acute, non-life-threatening situations, such asviralgastroenteritis(stomach flu).

Over-the-counter (OTC) antidiarrheal medications are found in most supermarkets, drug stores, and pharmacies. While OTC antidiarrheals work to alleviate symptoms, they rarely treat the underlying cause (for example, a virus or inflammation).

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A hand holding 2 white pills

For most adults, diarrhea happens occasionally and goes away on its own. In these cases, the cause probably remains a mystery, and medical intervention usually isn’t necessary.

For people who have chronic digestive diseases, such asinflammatory bowel disease (IBD), taking something OTC for diarrhea might seem like a good idea. However, many OTC antidiarrheals are recommended for limited use only and can interact with medications you are already taking. People with IBD should follow their healthcare provider’s advice to manage symptoms.

This article explores different OTC medications that relieve diarrhea symptoms, how to use anti-diarrheal drugs, and when to see a healthcare provider about your illness,

Diarrhea occurs when your intestines are unable to absorb water into the body. When stool contains too much water it causes loose bowel movements. You have diarrhea if you experience runny stools three or more times in one day.

Diarrhea is a common condition that can have a wide variety of causes. In many cases, diarrhea will go away after a few days without treatment, and the cause may never be known.

The most commoncauses of diarrheainclude:

When to Seek Medical CareConsult a healthcare provider if your diarrhea continues for more than a couple of days, you run a fever, experience severe pain, see blood or pus in your stool, or areunable to stay hydrated.

When to Seek Medical Care

Consult a healthcare provider if your diarrhea continues for more than a couple of days, you run a fever, experience severe pain, see blood or pus in your stool, or areunable to stay hydrated.

Dehydration can be a consequence of diarrhea. Possible symptoms include:

Focus on getting extra fluids (water, sports drinks) when sick. If you are having trouble keeping liquids down, try sucking on ice chips.

As already mentioned, OTC antidiarrheal drugs are used to slow down or stop diarrhea. They are primarily used to treat fairly routine illnesses, like food poisoning. In most cases, medical treatment isn’t necessary and the cause isn’t diagnosed.

When taking OTC diarrhea medication:

OTC antidiarrheals for IBSA recent study found that, among people with IBS and dyspepsia, 28% of those who self-medicated used the wrong medication to treat their GI complaints.

OTC antidiarrheals for IBS

A recent study found that, among people with IBS and dyspepsia, 28% of those who self-medicated used the wrong medication to treat their GI complaints.

For people who have chronic digestive diseases like irritable bowel syndrome (IBS) or inflammatory bowel disease (IBD), taking something OTC for diarrhea might seem like a good idea. However, while OTC antidiarrheals may work to alleviate diarrhea symptoms, they don’t treat the underlying causes of chronic bowel conditions. Your healthcare provider may recommend them, along with prescription medications and other treatment strategies, to control loose stools.

People who have hadj-pouch surgerymay be advised to use antidiarrheal medications, especially during recovery from the final surgery (takedown surgery) when the j-pouch is connected. Some people with j-pouches may use antidiarrheals on a long-term basis, while others might use them only as needed, such as when experiencing too many bowel movements a day.

Antidiarrheal medications are made from two main ingredients, loperamide and bismuth subsalicylate, which work in different ways.

There are prescription medications that are sometimes used for treating chronic diarrhea, and you can discuss with your doctor if those are appropriate for you.

Loperamide (Imodium)

Imodium, which can be purchased OTC, decreases the speed and number of intestinal contractions, slowing down diarrhea.

Side effects of loperamide can include abdominal pain, dry mouth, drowsiness, dizziness, constipation, nausea, and vomiting.People who have these side effects from loperamide may be unable to drive or do other activities that require concentration while taking it.

Also, if you have a history of heart rhythm problems, you should talk to your doctor before using loperamide.

If you haven’t used loperamide before or aren’t used to taking it regularly, avoid driving and operating heavy machinery until you know how it affects you.

Some people with J-pouches use this medication regularly and might get a prescription for it from a healthcare provider.

Bismuth Subsalicylate (Kaopectate and Pepto-Bismol)

Bismuth subsalicylate, found in Kaopectate and Pepto-Bismol, is better known for treating stomach upset. Still, it also works as an antidiarrheal and an anti-inflammatory, and it can inhibit the spread of some strains of bacteria that cause diarrhea.

Side effects ofPepto-Bismolcan include constipation, black stools, a black tongue, and (rarely)tinnitus. Overdoses of Pepto-Bismol can be dangerous, so only take the prescribed amount and don’t double up doses.

Summary

Frequently Asked QuestionsYes, various antidiarrheal medication options are available over the counter at pharmacies and many grocery stores. Pepto-Bismol and Kaopectate and their generic equivalents are two standard products. Alternatively, you can tryImodium, which slows intestinal contractions and reduces bouts of diarrhea.Learn MoreThe Safety of Taking Imodium to Treat DiarrheaYes, constipation is one side effect of Imodium. Other potential side effects include dizziness, drowsiness, headache, nausea, and vomiting. Most people don’t experience side effects from Imodium, but if you take other medications, talk to your healthcare provider first to see if there’s a potential for medicine interactions.A single dose of Imodium can last up to 14 to 38 hours.It takes about half an hour for the medicine to begin working.

Frequently Asked Questions

Yes, various antidiarrheal medication options are available over the counter at pharmacies and many grocery stores. Pepto-Bismol and Kaopectate and their generic equivalents are two standard products. Alternatively, you can tryImodium, which slows intestinal contractions and reduces bouts of diarrhea.Learn MoreThe Safety of Taking Imodium to Treat Diarrhea

Yes, various antidiarrheal medication options are available over the counter at pharmacies and many grocery stores. Pepto-Bismol and Kaopectate and their generic equivalents are two standard products. Alternatively, you can tryImodium, which slows intestinal contractions and reduces bouts of diarrhea.

Learn MoreThe Safety of Taking Imodium to Treat Diarrhea

Yes, constipation is one side effect of Imodium. Other potential side effects include dizziness, drowsiness, headache, nausea, and vomiting. Most people don’t experience side effects from Imodium, but if you take other medications, talk to your healthcare provider first to see if there’s a potential for medicine interactions.

A single dose of Imodium can last up to 14 to 38 hours.It takes about half an hour for the medicine to begin working.

10 Sources

Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

MedlinePlus.Diarrhea.

Houston Methodist.When to See a Doctor for Diarrhea.

Osmosis from Elsevier.Antidiarrheals: Nursing pharmacology.

Niknam R, Mousavi S, Safarpour A, Mahmoudi L, Mahmoudi P.Self-medication of irritable bowel syndrome and dyspepsia: How appropriate is it?J Res Pharm Pract. 2016;5(2):121-125. doi:10.4103/2279-042X.179576

Desai J, Elnaggar M, Hanfy AA, Doshi R.Toxic Megacolon: Background, Pathophysiology, Management Challenges and Solutions [published correction appears in Clin Exp Gastroenterol]. 2021 Jul 19;14:309-310].Clin Exp Gastroenterol. 2020;13:203-210. Published 2020 May 19. doi:10.2147/CEG.S200760

Hüttner FJ, Tenckhoff S, Jensen K, et al.Meta-analysis of reconstruction techniques after low anterior resection for rectal cancer.Br J Surg. 2015;102(7):735-745. doi:10.1002/bjs.9782

MedlinePlus.Loperamide.

Pepto Bismol.Symptoms.

Sahi N, Nguyen R, Santos C.Loperamide. StatPearls [Internet]. 2023.

American Society of Health-System Pharmacists. “Bismuth subsalicylate.” U.S. National Library of Medicine.American Society of Health-System Pharmacists. “Loperamide.” U.S. National Library of Medicine.

American Society of Health-System Pharmacists. “Bismuth subsalicylate.” U.S. National Library of Medicine.

American Society of Health-System Pharmacists. “Loperamide.” U.S. National Library of Medicine.

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