Table of ContentsView AllTable of ContentsNutrition and Acne: Is There a Link?Vitamin AB VitaminsVitamin CVitamin DVitamin EZincFrequently Asked Questions
Table of ContentsView All
View All
Table of Contents
Nutrition and Acne: Is There a Link?
Vitamin A
B Vitamins
Vitamin C
Vitamin D
Vitamin E
Zinc
Frequently Asked Questions
Though prescription medications are available to treat acne, many people first look to vitamins and minerals, including nutritional supplements.
Eating a nutritious diet is important for your overall well-being, including skin health. However, research into the benefits, risks, and effectiveness of oral vitamin supplementation for acne is lacking.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
Getty Images / Doucefleur
There are a few studies that have suggested certain foods may play a role in the development of acne, such as dairy and high-sugar diets.
There are also a few studies that suggest oxidative stress is a possible cause of acne. People with acne seem to have lower blood levels ofantioxidants. Antioxidants may be a possible therapy for treating acne,but this research has yet to prove this.
A link between nutrition and acne is, at best, a theory. Few studies meet the high scientific standards required to change current practice recommendations to include supplementation.
Below, the vitamins and minerals that may affect acne are individually reviewed.
A Note on Supplement UseA healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider, should individualize and vet supplement use. No supplement’s purpose is to treat, cure, or prevent disease.
A Note on Supplement Use
A healthcare professional, such as a registered dietitian, pharmacist, or healthcare provider, should individualize and vet supplement use. No supplement’s purpose is to treat, cure, or prevent disease.
There are two types ofvitamin Ain our diets: preformed vitamin A and provitamin A.
Preformed vitamin A is found in animal food sources, such as eggs, fish, and organ meats. Provitamin A carotenoids (such asbeta carotene) are found in plant sources. The body converts provitamin A to vitamin A.
Good sources of vitamin A in the diet include beef, liver, and some fish, such as herring. Plant sources of vitamin A include sweet potatoes, carrots, pumpkin, and cantaloupe.
Some research has found that taking supplemental vitamin A improved acne for some of its participants.
Further, study authors suggest that vitamin A can serve as a substitute forisotretinoin, a prescription drug for treating acne. However, it is important to note that the amounts of vitamin A provided were very high and, in some cases, may have exceeded what’s known as the tolerable upper limit (TUL). Such quantities of supplementation should only occur under medical supervision.
Vitamin A is afat-soluble vitaminand can accumulate in the body when consumed in high amounts. To preventvitamin A toxicity, adults should not exceed the TUL of 3,000 micrograms of preformed vitamin A daily.
Vitamin A can be found in stand-alone supplements or multivitamins. Trying to meet vitamin and mineral requirements through diet alone first is best. However, not everyone can do this, and some may want to ensure they meet their requirements through supplements. In this case, a simple multivitamin may prove beneficial.
What to Know About IsotretinoinIsotretinoin is a prescription medication used for the treatment of severe acne.Previously, it was marketed under the brand name Accutane. Now, it is marketed as Absorica, Claravis, Amnesteem, Myorisan, and Zenatane.
What to Know About Isotretinoin
Isotretinoin is a prescription medication used for the treatment of severe acne.Previously, it was marketed under the brand name Accutane. Now, it is marketed as Absorica, Claravis, Amnesteem, Myorisan, and Zenatane.
There are eight different B vitamins:
Food sources of each may vary, but generally speaking, good sources of vitamin B include foods like whole grains, eggs, nuts, seeds, and meat.
There is little published research on how vitamin B supplements affect acne.Niacinamide, a form of vitamin B3, has been studied for several skin issues, including acne. However, the results of this have been unclear.
Pantothenic acid (vitamin B5) has also been studied for acne. A small clinical trial found that it reduced acne blemishes compared to a placebo. However, more extensive studies are necessary to confirm these findings.
Other forms of vitamin B, including vitamin B12, B6, and B2, have been linked to worsening existing acne.
Vitamin C(also known as ascorbic acid) is a water-soluble vitamin found mostly in fruits and vegetables in the diet. The requirements for vitamin C in adults range from 65–95 milligrams daily, though pregnant and nursing people and smokers need more.
Eating bell peppers, oranges, orange juice, kiwis, strawberries, and more can easily meet daily vitamin C requirements.
There is very little research on oral vitamin C supplementation for treating acne. However, one study found that people who took a dietary supplement containing vitamin C (and several other nutrients) for acne experienced fewer side effects from the medication isotretinoin.
Vitamin C supplementsare available as individual supplements or in multivitamin preparations. Because vitamin C is water soluble, excess amounts are excreted in the urine. The Food and Nutrition Board recommends that adults do not exceed 2,000 milligrams daily of vitamin C.
Vitamin Dis a fat-soluble vitamin that is available in the foods we eat as well as in supplements. The body also makes vitamin D when it’s exposed to sunlight.
Good sources of vitamin D include fish, beef liver, egg yolks, cheese, and mushrooms.
The Recommended Dietary Allowance (RDA) for vitamin D ranges from 15–20 micrograms daily for adults.
Some research suggests that vitamin D deficiency occurs more frequently in people with acne.However, this does not establish causation, meaning it doesn’t confirm that a deficiency causes the acne. Yet, other studies have not found plasma vitamin D levels correlating with acne occurrence.There is insufficient evidence to suggest that supplementing vitamin D can cure acne.
Generally speaking, low plasma vitamin D levels should be supplemented until they return to normal levels whether the person in question has acne or not. Your healthcare provider can arrange to have your vitamin D levels checked and recommendan appropriate supplementif necessary.
Vitamin E(also referred to as alpha-tocopherol) is another fat-soluble vitamin that functions mostly as an antioxidant. It is obtained mostly from nuts, seeds, and vegetable oils but also fortified cereals and leafy green vegetables.
The RDA for vitamin E for adults is 15 milligrams.
Some researchers found that people with acne treated with isotretinoin had lower plasma levels of vitamin E after treatment.But then supplementing 20 micrograms of vitamin E daily did not lessen the side effects of isotretinoin.The subjects of these studies were older adults, and the findings may not apply to other age groups.
There are some possible risks associated with excessive vitamin E supplementation. Vitamin E in high doses may lead to hemorrhage, prostate cancer, or mortality. Therefore, 1,000 milligrams of alpha-tocopherol daily has been established as the upper limit of how much anyone should absorb.
Zincis a mineral found in foods and available as a supplement. It is also commonly added to cold remedies and found in cold lozenges.
The RDA for zinc for adults ranges from 8–12 milligrams daily.
The best food sources of zinc include meat, fish, and seafood. Oysters top the list at 32 milligrams per 3-ounce serving.
Research has found that people with acne tend to have lower serum zinc levels. Additionally, supplemental zinc reduced the number of inflammatory papules in those with acne compared to those who did not take it.
Other studies have found thatzinc supplementsimproved acne, but the doses of zinc taken were very high and exceeded the set TUL for daily intake.
Excessive zinc intake through supplements may interfere with magnesium and copper absorption. Adults should avoid doses in excess of the TUL of 40 milligrams daily.
Summary
Several vitamin and mineral supplements are marketed for skin health. However, research doesn’t support the use of oral vitamin supplements for the treatment of acne.
Generally speaking, the purpose of nutritional supplements is not to treat or cure conditions. Consult a dermatologist if you are looking for solutions for your acne.
For people with acne, a healthful diet that includes a variety of foods, including adequate protein from meats, fish, fruits, and vegetables, is recommended. This will help ensure your minimum vitamin and mineral requirements are met.
If this is not possible, supplementing with a simple multivitamin with minerals can ensure these needs are met. Be sure to read the supplement facts label and look for supplements that avoid doses in excess of their upper limits.
Always speak with a healthcare provider before taking a supplement to ensure that the supplement and its dosage are appropriate for your individual needs.
Frequently Asked QuestionsThere is not enough research to support using oral vitamin supplements for acne scars. However, there may be some topical creams or lotions that contain useful vitamins. You should discuss these options with your healthcare provider or a dermatologist.There is not enough research to support taking oral vitamins or minerals to treat acne. Though more studies of zinc show that it may help with acne, the doses provided to reach this result were too high.Eating a healthful diet with a variety of foods is most appropriate to make sure you are meeting your vitamin and mineral requirements. Including enough fruits and vegetables will help to meet daily requirements for vitamins A and C. Including nuts and seeds can provide vitamin E. Including protein sources like meats and fish can ensure adequate zinc intake. If eating a variety of healthy food is a challenge, a multivitamin can help to make sure you are meeting your daily requirements.
There is not enough research to support using oral vitamin supplements for acne scars. However, there may be some topical creams or lotions that contain useful vitamins. You should discuss these options with your healthcare provider or a dermatologist.
There is not enough research to support taking oral vitamins or minerals to treat acne. Though more studies of zinc show that it may help with acne, the doses provided to reach this result were too high.
Eating a healthful diet with a variety of foods is most appropriate to make sure you are meeting your vitamin and mineral requirements. Including enough fruits and vegetables will help to meet daily requirements for vitamins A and C. Including nuts and seeds can provide vitamin E. Including protein sources like meats and fish can ensure adequate zinc intake. If eating a variety of healthy food is a challenge, a multivitamin can help to make sure you are meeting your daily requirements.
18 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Kucharska A, Szmurło A, Sińska B.Significance of diet in treated and untreated acne vulgaris.Postepy Dermatol Alergol. 2016;33(2):81-86. doi:10.5114/ada.2016.59146National Institutes of Health Office of Dietary Supplements.Vitamin A and carotenoids health professional fact sheet.Cook MK, Perche PO, Feldman SR.Oral vitamin A for acne management: a possible substitute for isotretinoin.J Drugs Dermatol. 2022;21(6):683-686. doi:10.36849/JDD.6781DailyMed.Label: isotretinoin capsule, liquid filled.Hanna M, Jaqua E, Nguyen V, Clay J.B vitamins: functions and uses in medicine.Perm J. 2022;26(2):89-97. doi:10.7812/TPP/21.204Walocko FM, Eber AE, Keri JE, et al.The role of nicotinamide in acne treatment.Dermatol Ther. 2017;30(5). doi:10.1111/dth.12481Yang M, Moclair B, Hatcher V, et al.A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne.Dermatol Ther (Heidelb). 2014;4(1):93-101. doi:10.1007/s13555-014-0052-3Elgharably N, Al Abadie M, Al Abadie M, et al.Vitamin B group levels and supplementations in dermatology.Dermatol Reports. 2022;15(1):9511. doi:10.4081/dr.2022.9511.National Institutes of Health Office of Dietary Supplements.Vitamin C.Fabbrocini G, Cameli N, Lorenzi S, et al.A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.G Ital Dermatol Venereol. 2014;149(4):441-445.National Institute of Health Office of Dietary Supplements.Vitamin D. National Institutes of Health. Sept. 2023.Lim SK, Ha JM, Lee YH, et al.Comparison of vitamin D levels in patients with and without acne: a case-control study combined with a randomized controlled trial.PLoS One. 2016;11(8):e0161162. doi:10.1371/journal.pone.0161162Al-Taiar A, AlKhabbaz M, Rahman A, et al.Plasma 25-hydroxy vitamin D is not associated with acne vulgaris.Nutrients. 2018; 10(10):1525. doi:10.3390/nu10101525National Institutes of Health Office of Dietary Supplements.Vitamin E.Aktürk AŞ, Güzel S, Bulca S, et al.Effects of isotretinoin on serum vitamin E levels in patients with acne.Int J Dermatol. 2013;52(3):363-366. doi:10.1111/j.1365-4632.2012.05676.xKus S, Gün D, Demirçay Z, Sur H.Vitamin E does not reduce the side effects of isotretinoin in the treatment of acne vulgaris.Int J Dermatol. 2005;44(3):248-251. doi:10.1111/j.1365-4632.2004.02072.xNational Institutes of Health Office of Dietary Supplements.Zinc.Yee BE, Richards P, Sui JY, Marsch AF.Serum zinc levels and efficacy of zinc treatment in acne vulgaris: a systematic review and meta-analysis.Dermatol Ther. 2020;33(6):e14252. doi:10.1111/dth.14252
18 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Kucharska A, Szmurło A, Sińska B.Significance of diet in treated and untreated acne vulgaris.Postepy Dermatol Alergol. 2016;33(2):81-86. doi:10.5114/ada.2016.59146National Institutes of Health Office of Dietary Supplements.Vitamin A and carotenoids health professional fact sheet.Cook MK, Perche PO, Feldman SR.Oral vitamin A for acne management: a possible substitute for isotretinoin.J Drugs Dermatol. 2022;21(6):683-686. doi:10.36849/JDD.6781DailyMed.Label: isotretinoin capsule, liquid filled.Hanna M, Jaqua E, Nguyen V, Clay J.B vitamins: functions and uses in medicine.Perm J. 2022;26(2):89-97. doi:10.7812/TPP/21.204Walocko FM, Eber AE, Keri JE, et al.The role of nicotinamide in acne treatment.Dermatol Ther. 2017;30(5). doi:10.1111/dth.12481Yang M, Moclair B, Hatcher V, et al.A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne.Dermatol Ther (Heidelb). 2014;4(1):93-101. doi:10.1007/s13555-014-0052-3Elgharably N, Al Abadie M, Al Abadie M, et al.Vitamin B group levels and supplementations in dermatology.Dermatol Reports. 2022;15(1):9511. doi:10.4081/dr.2022.9511.National Institutes of Health Office of Dietary Supplements.Vitamin C.Fabbrocini G, Cameli N, Lorenzi S, et al.A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.G Ital Dermatol Venereol. 2014;149(4):441-445.National Institute of Health Office of Dietary Supplements.Vitamin D. National Institutes of Health. Sept. 2023.Lim SK, Ha JM, Lee YH, et al.Comparison of vitamin D levels in patients with and without acne: a case-control study combined with a randomized controlled trial.PLoS One. 2016;11(8):e0161162. doi:10.1371/journal.pone.0161162Al-Taiar A, AlKhabbaz M, Rahman A, et al.Plasma 25-hydroxy vitamin D is not associated with acne vulgaris.Nutrients. 2018; 10(10):1525. doi:10.3390/nu10101525National Institutes of Health Office of Dietary Supplements.Vitamin E.Aktürk AŞ, Güzel S, Bulca S, et al.Effects of isotretinoin on serum vitamin E levels in patients with acne.Int J Dermatol. 2013;52(3):363-366. doi:10.1111/j.1365-4632.2012.05676.xKus S, Gün D, Demirçay Z, Sur H.Vitamin E does not reduce the side effects of isotretinoin in the treatment of acne vulgaris.Int J Dermatol. 2005;44(3):248-251. doi:10.1111/j.1365-4632.2004.02072.xNational Institutes of Health Office of Dietary Supplements.Zinc.Yee BE, Richards P, Sui JY, Marsch AF.Serum zinc levels and efficacy of zinc treatment in acne vulgaris: a systematic review and meta-analysis.Dermatol Ther. 2020;33(6):e14252. doi:10.1111/dth.14252
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Kucharska A, Szmurło A, Sińska B.Significance of diet in treated and untreated acne vulgaris.Postepy Dermatol Alergol. 2016;33(2):81-86. doi:10.5114/ada.2016.59146National Institutes of Health Office of Dietary Supplements.Vitamin A and carotenoids health professional fact sheet.Cook MK, Perche PO, Feldman SR.Oral vitamin A for acne management: a possible substitute for isotretinoin.J Drugs Dermatol. 2022;21(6):683-686. doi:10.36849/JDD.6781DailyMed.Label: isotretinoin capsule, liquid filled.Hanna M, Jaqua E, Nguyen V, Clay J.B vitamins: functions and uses in medicine.Perm J. 2022;26(2):89-97. doi:10.7812/TPP/21.204Walocko FM, Eber AE, Keri JE, et al.The role of nicotinamide in acne treatment.Dermatol Ther. 2017;30(5). doi:10.1111/dth.12481Yang M, Moclair B, Hatcher V, et al.A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne.Dermatol Ther (Heidelb). 2014;4(1):93-101. doi:10.1007/s13555-014-0052-3Elgharably N, Al Abadie M, Al Abadie M, et al.Vitamin B group levels and supplementations in dermatology.Dermatol Reports. 2022;15(1):9511. doi:10.4081/dr.2022.9511.National Institutes of Health Office of Dietary Supplements.Vitamin C.Fabbrocini G, Cameli N, Lorenzi S, et al.A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.G Ital Dermatol Venereol. 2014;149(4):441-445.National Institute of Health Office of Dietary Supplements.Vitamin D. National Institutes of Health. Sept. 2023.Lim SK, Ha JM, Lee YH, et al.Comparison of vitamin D levels in patients with and without acne: a case-control study combined with a randomized controlled trial.PLoS One. 2016;11(8):e0161162. doi:10.1371/journal.pone.0161162Al-Taiar A, AlKhabbaz M, Rahman A, et al.Plasma 25-hydroxy vitamin D is not associated with acne vulgaris.Nutrients. 2018; 10(10):1525. doi:10.3390/nu10101525National Institutes of Health Office of Dietary Supplements.Vitamin E.Aktürk AŞ, Güzel S, Bulca S, et al.Effects of isotretinoin on serum vitamin E levels in patients with acne.Int J Dermatol. 2013;52(3):363-366. doi:10.1111/j.1365-4632.2012.05676.xKus S, Gün D, Demirçay Z, Sur H.Vitamin E does not reduce the side effects of isotretinoin in the treatment of acne vulgaris.Int J Dermatol. 2005;44(3):248-251. doi:10.1111/j.1365-4632.2004.02072.xNational Institutes of Health Office of Dietary Supplements.Zinc.Yee BE, Richards P, Sui JY, Marsch AF.Serum zinc levels and efficacy of zinc treatment in acne vulgaris: a systematic review and meta-analysis.Dermatol Ther. 2020;33(6):e14252. doi:10.1111/dth.14252
Kucharska A, Szmurło A, Sińska B.Significance of diet in treated and untreated acne vulgaris.Postepy Dermatol Alergol. 2016;33(2):81-86. doi:10.5114/ada.2016.59146
National Institutes of Health Office of Dietary Supplements.Vitamin A and carotenoids health professional fact sheet.
Cook MK, Perche PO, Feldman SR.Oral vitamin A for acne management: a possible substitute for isotretinoin.J Drugs Dermatol. 2022;21(6):683-686. doi:10.36849/JDD.6781
DailyMed.Label: isotretinoin capsule, liquid filled.
Hanna M, Jaqua E, Nguyen V, Clay J.B vitamins: functions and uses in medicine.Perm J. 2022;26(2):89-97. doi:10.7812/TPP/21.204
Walocko FM, Eber AE, Keri JE, et al.The role of nicotinamide in acne treatment.Dermatol Ther. 2017;30(5). doi:10.1111/dth.12481
Yang M, Moclair B, Hatcher V, et al.A randomized, double-blind, placebo-controlled study of a novel pantothenic acid-based dietary supplement in subjects with mild to moderate facial acne.Dermatol Ther (Heidelb). 2014;4(1):93-101. doi:10.1007/s13555-014-0052-3
Elgharably N, Al Abadie M, Al Abadie M, et al.Vitamin B group levels and supplementations in dermatology.Dermatol Reports. 2022;15(1):9511. doi:10.4081/dr.2022.9511.
National Institutes of Health Office of Dietary Supplements.Vitamin C.
Fabbrocini G, Cameli N, Lorenzi S, et al.A dietary supplement to reduce side effects of oral isotretinoin therapy in acne patients.G Ital Dermatol Venereol. 2014;149(4):441-445.
National Institute of Health Office of Dietary Supplements.Vitamin D. National Institutes of Health. Sept. 2023.
Lim SK, Ha JM, Lee YH, et al.Comparison of vitamin D levels in patients with and without acne: a case-control study combined with a randomized controlled trial.PLoS One. 2016;11(8):e0161162. doi:10.1371/journal.pone.0161162
Al-Taiar A, AlKhabbaz M, Rahman A, et al.Plasma 25-hydroxy vitamin D is not associated with acne vulgaris.Nutrients. 2018; 10(10):1525. doi:10.3390/nu10101525
National Institutes of Health Office of Dietary Supplements.Vitamin E.
Aktürk AŞ, Güzel S, Bulca S, et al.Effects of isotretinoin on serum vitamin E levels in patients with acne.Int J Dermatol. 2013;52(3):363-366. doi:10.1111/j.1365-4632.2012.05676.x
Kus S, Gün D, Demirçay Z, Sur H.Vitamin E does not reduce the side effects of isotretinoin in the treatment of acne vulgaris.Int J Dermatol. 2005;44(3):248-251. doi:10.1111/j.1365-4632.2004.02072.x
National Institutes of Health Office of Dietary Supplements.Zinc.
Yee BE, Richards P, Sui JY, Marsch AF.Serum zinc levels and efficacy of zinc treatment in acne vulgaris: a systematic review and meta-analysis.Dermatol Ther. 2020;33(6):e14252. doi:10.1111/dth.14252
Meet Our Medical Expert Board
Share Feedback
Was this page helpful?Thanks for your feedback!What is your feedback?OtherHelpfulReport an ErrorSubmit
Was this page helpful?
Thanks for your feedback!
What is your feedback?OtherHelpfulReport an ErrorSubmit
What is your feedback?
