Table of ContentsView AllTable of ContentsUsesSide EffectsPrecautionsDosageToxicityInteractionsSimilar SupplementsSources & What to Look For
Table of ContentsView All
View All
Table of Contents
Uses
Side Effects
Precautions
Dosage
Toxicity
Interactions
Similar Supplements
Sources & What to Look For
Selenomethionine(SeMet) is a mineral important for normal thyroid gland function. Although some research has explored SeMet’s ability to lower the risk of heart disease, decrease age-related cognitive decline, and treat ulcerative colitis, more research is needed to confirm these benefits.
Selenomethionine is one of the main natural forms of selenium. This nutrient is found in many foods, including nuts, whole grains, meat, eggs, and dairy. It combines with proteins in the body to form antioxidants called selenoproteins. These compounds help protect againstfree radicals, the unstable molecules that can cause damage to cells in your body.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
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Uses of Selenomethionine
Much of the research on SeMet has centered around thyroid disease, cancer, and heart disease prevention. It also has been studied for its role in mental health and how it may prevent cognitive decline.
Thyroid Disease
Selenium levels in the human body are highest in the thyroid gland. The mineral plays a key role in thyroid metabolism and making thyroid hormone. Because of this, selenomethionine has been studied for its effects on thyroid diseases.
One study looked at 192 people who had hypothyroidism, or mildly low and symptom-free thyroid levels because ofHashimoto’s disease. For the study, participants were given either 83 mcg of oral SeMet or aplaceboevery day for four months.
At the end of the study, 31.3% of people who took SeMet had restored thyroid function compared to just 3.1% in the placebo group.
Another study looked at how children and teens with autoimmunethyroiditiswould respond to SeMet.Seventy-one participants were given 200 mcg of selenomethionine or a placebo daily for six months.
Thyroid Blood Tests: Types and What Results Mean
Another study looked at whether the supplements helped protect against thyroid autoimmunity during and after pregnancy.Forty-five participants who had thyroiditis in pregnancy were given either SeMet or a placebo. They were evaluated at around 10 weeks gestation, 36 weeks gestation, and about six months after delivery.
Study results found:
Based on these three studies, it appears SeMet may help with some thyroid conditions in certain people, including adults, pregnant women, children, and adolescents.
What Is Keshan Disease?Keshan disease is the only known disorder linked directly to low levels of selenium. It damages the heart muscle, leading to heart failure and other heart problems. The disease is often found in places with low soil levels of selenium, meaning the mineral levels in food grown there may be lower too. Keshan disease was discovered in 1935 in China, where it continues to cause fatal heart problems in children and younger women today.
What Is Keshan Disease?
Keshan disease is the only known disorder linked directly to low levels of selenium. It damages the heart muscle, leading to heart failure and other heart problems. The disease is often found in places with low soil levels of selenium, meaning the mineral levels in food grown there may be lower too. Keshan disease was discovered in 1935 in China, where it continues to cause fatal heart problems in children and younger women today.
Cancer
Selenomethionine does not seem to help with cancer prevention.
The Adenomatous Colorectal Polyp (ACP) study was designed to see whether SeMet or vitamin E lowered the rate ofcolon and rectal cancers, as well as adenomas—tumors or abnormal growths that can lead to these cancers.
The study, based on a subset of people in a wider research program, included 2,286 men with one or more cancer-related adenomas who were treated for seven to 12 years. Participants were divided into four groups: selenium only, vitamin E only, selenium + vitamin E, and placebo only.
Participants who got selenomethionine, 34.2% were diagnosed with adenomas at least one year later, compared to 35.7% in the group given a placebo.This was not a significant difference and led to the conclusion that taking SeMet had no effect on colon cancer prevention for these people.
A 2018 review of previous studies also found that taking selenium, including in the form of selenomethionine, did not have an impact on any type of cancer risk.
Adenomatous Polyp in the Colon
Heart Disease
A 2015 review found that when selenium intake was higher, heart disease risk was lower. Yet the researchers were unable to tell if it was selenium alone that actually prevented heart disease or if there were other contributing factors.
More clinical trials are needed to better understand the SeMet-heart risk connection.
Cognitive Function
Selenium levels in the body often decline with age.Because of this, low selenium may be linked to age-related cognitive declines, possibly because of the subsequent reduction in its impact as an antioxidant. However, study results are mixed.
Alzheimer’s diseaseis often diagnosed in older people and leads to progressive cognitive decline. Yet there is no clear evidence to support a role for selenium—in SeMet form or otherwise—for treating it.
Selenium may one day be shown to prevent cognitive decline, but currently more studies are needed.
Dementia and Related Cognitive Disorders
Ulcerative Colitis
Ulcerative colitis(UC) is an inflammatory bowel disease that mostly impacts the large colon. It can create discomfort and nutrient deficiencies.A study published in 2023 suggested 200 mcg of selenomethionine daily for 10 weeks decreased UC symptoms and interleukin-17 (a marker of inflammation in the body) and increased quality of life in people with mild to moderate UC.More research is needed.
What Are the Side Effects of Selenomethionine?
Generally, side effects will only occur when there is too much selenium in the body. This is rare when taking supplements as directed, but it can happen if the doses you take are too high.
Some people may experience mild side effects when taking selenomethionine at lower doses, including:
Always talk with your healthcare provider before taking any dietary supplement, including SeMet. Be sure to follow the directions on the product label.
What Is the Difference Between Selenomethionine and Selenium?Selenomethionine is a natural form of selenium. It is the same form of selenium found naturally in the foods you eat. Seafood, nuts, and meat are all good dietary sources of selenomethionine.
What Is the Difference Between Selenomethionine and Selenium?
Selenomethionine is a natural form of selenium. It is the same form of selenium found naturally in the foods you eat. Seafood, nuts, and meat are all good dietary sources of selenomethionine.
Selenomethionine can be toxic at high doses, especially when taken long-term. Taking lower doses for long periods of time may increase your risk of developing diabetes.
Dosage: How Much Selenomethionine Should I Take?
Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs.
The National Academies of Sciences sets the suggested daily amount needed for vitamins and minerals, including selenium. The Recommended Dietary Allowance (RDA) for selenium is based on age and life stage, including people who are pregnant or breastfeeding. The RDA includes your intake from all sources, such as food, drinks, and supplements.
What Happens if I Take Too Much Selenomethionine?
Taking too much selenium for long periods can cause selenosis. This is the medical term for selenium poisoning. People with selenosis may experience symptoms such as:
Selenosis can also cause nerve damage. People with severe selenosis may experience:
Selenium may increase the risk of bleeding or bruising if you take it with blood thinners such as warfarin or heparin. It may have a similar effect if you take it with aspirin.
In a rat study, selenium increased or extended the time barbiturates lasted. These findings may not apply to humans. However, let your healthcare provider know if you take barbiturates like Butisol (butabarbital) or Luminal (phenobarbital) and selenium supplements.
Cisplatin, a chemotherapy medication, reduces selenium levels.While some evidence suggests selenium might help Cisplatin toxicity, other studies suggest more research is needed to prove this effect.
Several other supplements have the same functions as selenomethionine and are possible alternatives:
Sources of Selenomethionine and What To Look For
Most people can get enough selenium from the foods they eat. You may have trouble absorbing selenium, however, if you are on dialysis, if you have a GI condition such as Crohn’s disease, or if you have HIV. In these cases, a selenium supplement may be helpful.
Food Sources of Selenomethionine
Foods high in selenium include but aren’t limited to the following:
FoodServing size- ounces (oz)Micrograms (mcg)% Daily Value (DV)Brazil Nuts1 oz. (6 to 8 nuts)544 mcg989% DVYellowfin tuna3 oz. cooked92 mcg167% DVOysters3 oz.64.5 mcg117% DVHalibut3 oz. cooked47 mcg85% DVSardines3 oz.45 mcg82% DVHam3 oz. roasted42 mcg76% DVShrimp3 oz. cooked40 mcg73% DVBeef, bottom round3 oz. roasted33mcg60% DVMacaroni, enriched1 cup cooked31.7 mcg58% DVTurkey3 oz. roasted31 mcg56% DVSalmon3 oz. cooked30.2 mcg55% DVClams3 oz.26 mcg47.5% DVChicken, light meat3 oz. roasted22 mcg40% DVCottage Cheese, 1% fat1 cup20 mcg36% DVPita bread6.5 inches16.3 mcg30% DVYogurt, plain, lowfat1 cup8 mcg15% DVMilk, 1% fat1 cup8 mcg15% DVRaisin bread1 piece5 mcg9.1% DVBran flakes cereal3/4 cup2.67 mcg4.9% DVSelenomethionine SupplementsSeMet is a common form of selenium. SeMet supplements are most often available in the form of tablets or capsules.Guide to Dietary Supplements and Thyroid DiseaseSummarySelenomethionine is present in many foods you eat, but it’s also sold as a nutritional supplement. While SeMet may have health benefits, notably for thyroid function, researchers still have not shown clear benefits for cancer, heart disease, cognitive decline, or ulcerative colitis.While supplements may have health benefits, it’s important to ask your healthcare provider before starting a supplement regimen, especially if you have pre-existing health conditions or take other medications.
Selenomethionine Supplements
SeMet is a common form of selenium. SeMet supplements are most often available in the form of tablets or capsules.
Guide to Dietary Supplements and Thyroid Disease
Summary
Selenomethionine is present in many foods you eat, but it’s also sold as a nutritional supplement. While SeMet may have health benefits, notably for thyroid function, researchers still have not shown clear benefits for cancer, heart disease, cognitive decline, or ulcerative colitis.
While supplements may have health benefits, it’s important to ask your healthcare provider before starting a supplement regimen, especially if you have pre-existing health conditions or take other medications.
23 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Pirola I, Gandossi E, Agosti B, Delbarba A, Cappelli C.Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis.Endokrynol Pol. 2016;67(6):567-571. doi:10.5603/EP.2016.0064Kyrgios I, Giza S, Kotanidou EP, et al.l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.J Clin Pharm Ther. 2019;44(1):102-108. doi:10.1111/jcpt.12765Mantovani G, Isidori AM, Moretti C, et al.Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial.Endocrine. 2019;66(3):542-550. doi:10.1007/s12020-019-01958-1Shi Y, Yang W, Tang X, Yan Q, Cai X, Wu F.Keshan disease: a potentially fatal endemic cardiomyopathy in remote mountains of china.Front Pediatr. 2021;9:576916. doi: 10.3389/fped.2021.576916Lance P, Alberts DS, Thompson PA, et al.Colorectal adenomas in participants of the SELECT randomized trial of selenium and vitamin E for prostate cancer prevention.Cancer Prev Res (Phila). 2017;10(1):45-54. doi:10.1158/1940-6207.CAPR-16-0104Vinceti M, Filippini T, Del Giovane C, et al.Selenium for preventing cancer.Cochrane Database Syst Rev. 2018;1(1):CD005195. doi:10.1002/14651858.CD005195.pub4Benstoem C, Goetzenich A, Kraemer S, et al.Selenium and its supplementation in cardiovascular disease–what do we know?.Nutrients. 2015;7(5):3094-3118. doi:10.3390/nu7053094Robberecht H, De Bruyne T, Davioud-Charvet E, Mackrill J, Hermans N.Selenium status in elderly people: Longevity and age-related diseases.Curr Pharm Des. 2019;25(15):1694-1706. doi:10.2174/1381612825666190701144709Loef M, Schrauzer GN, Walach H.Selenium and Alzheimer’s disease: A systematic review.J Alzheimers Dis. 2011;26(1):81-104. doi:10.3233/JAD-2011-110414National Institute of Diabetes and Digestive and Kidney Diseases.Ulcerative colitis.Khazdouz M, Daryani NE, Cheraghpour M, et al.The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr. 2023 Dec;62(8):3125-3134. doi: 10.1007/s00394-023-03214-9National Institutes of Health Office of Dietary Supplements.Selenium.International Joint Commission Health Professionals Advisory Board.Selenosis.Donaldson M, Touger-Decker R.Vitamin and mineral supplements: friend or foe when combined with medications?J Am Dent Assoc. 2014 Nov;145(11):1153-8. doi: 10.14219/jada.2014.78Debski B, Milner JA.Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem. 2004 Sep;15(9):548-53. doi: 10.1016/j.jnutbio.2004.04.002Nordio M, Basciani S.Treatment with myo-inositol and selenium ensures euthyroidism in patients with autoimmune thyroiditis.Int J Endocrinol. 2017;2017:2549491. doi:10.1155/2017/2549491U.S. Department of Agriculture FoodData Central.Mollusks, oyster, pacific, raw.U.S. Department of Agriculture FoodData Central.Pasta, cooked, enriched, no salt added.U.S. Department of Agriculture FoodData Central.Fish, salmon, sockeye, cooked, dry heat.U.S. Department of Agriculture FoodData Central.Mollusks, clams, mixed species, raw.U.S. Department of Agriculture FoodData Central.Bread, pita, white, enriched.U.S. Department of Agriculture FoodData Central.Bread, raisin, enriched.U.S. Department of Agriculture FoodData Central.Cereals ready-to-eat, Ralston enriched wheat bran flakes.Additional ReadingNational Center for Biotechnology Information.PubChem compound summary for CID 15103, selenomethionine.Rayman MP.Selenium and human health.The Lancet. 2012;379(9822):1256-1268. doi:10.1016/S0140-6736(11)61452-9Schrauzer GN.Selenomethionine: a review of its nutritional significance, metabolism and toxicity.J Nutr. 2000;130(7):1653-1656. doi:10.1093/jn/130.7.1653
23 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Pirola I, Gandossi E, Agosti B, Delbarba A, Cappelli C.Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis.Endokrynol Pol. 2016;67(6):567-571. doi:10.5603/EP.2016.0064Kyrgios I, Giza S, Kotanidou EP, et al.l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.J Clin Pharm Ther. 2019;44(1):102-108. doi:10.1111/jcpt.12765Mantovani G, Isidori AM, Moretti C, et al.Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial.Endocrine. 2019;66(3):542-550. doi:10.1007/s12020-019-01958-1Shi Y, Yang W, Tang X, Yan Q, Cai X, Wu F.Keshan disease: a potentially fatal endemic cardiomyopathy in remote mountains of china.Front Pediatr. 2021;9:576916. doi: 10.3389/fped.2021.576916Lance P, Alberts DS, Thompson PA, et al.Colorectal adenomas in participants of the SELECT randomized trial of selenium and vitamin E for prostate cancer prevention.Cancer Prev Res (Phila). 2017;10(1):45-54. doi:10.1158/1940-6207.CAPR-16-0104Vinceti M, Filippini T, Del Giovane C, et al.Selenium for preventing cancer.Cochrane Database Syst Rev. 2018;1(1):CD005195. doi:10.1002/14651858.CD005195.pub4Benstoem C, Goetzenich A, Kraemer S, et al.Selenium and its supplementation in cardiovascular disease–what do we know?.Nutrients. 2015;7(5):3094-3118. doi:10.3390/nu7053094Robberecht H, De Bruyne T, Davioud-Charvet E, Mackrill J, Hermans N.Selenium status in elderly people: Longevity and age-related diseases.Curr Pharm Des. 2019;25(15):1694-1706. doi:10.2174/1381612825666190701144709Loef M, Schrauzer GN, Walach H.Selenium and Alzheimer’s disease: A systematic review.J Alzheimers Dis. 2011;26(1):81-104. doi:10.3233/JAD-2011-110414National Institute of Diabetes and Digestive and Kidney Diseases.Ulcerative colitis.Khazdouz M, Daryani NE, Cheraghpour M, et al.The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr. 2023 Dec;62(8):3125-3134. doi: 10.1007/s00394-023-03214-9National Institutes of Health Office of Dietary Supplements.Selenium.International Joint Commission Health Professionals Advisory Board.Selenosis.Donaldson M, Touger-Decker R.Vitamin and mineral supplements: friend or foe when combined with medications?J Am Dent Assoc. 2014 Nov;145(11):1153-8. doi: 10.14219/jada.2014.78Debski B, Milner JA.Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem. 2004 Sep;15(9):548-53. doi: 10.1016/j.jnutbio.2004.04.002Nordio M, Basciani S.Treatment with myo-inositol and selenium ensures euthyroidism in patients with autoimmune thyroiditis.Int J Endocrinol. 2017;2017:2549491. doi:10.1155/2017/2549491U.S. Department of Agriculture FoodData Central.Mollusks, oyster, pacific, raw.U.S. Department of Agriculture FoodData Central.Pasta, cooked, enriched, no salt added.U.S. Department of Agriculture FoodData Central.Fish, salmon, sockeye, cooked, dry heat.U.S. Department of Agriculture FoodData Central.Mollusks, clams, mixed species, raw.U.S. Department of Agriculture FoodData Central.Bread, pita, white, enriched.U.S. Department of Agriculture FoodData Central.Bread, raisin, enriched.U.S. Department of Agriculture FoodData Central.Cereals ready-to-eat, Ralston enriched wheat bran flakes.Additional ReadingNational Center for Biotechnology Information.PubChem compound summary for CID 15103, selenomethionine.Rayman MP.Selenium and human health.The Lancet. 2012;379(9822):1256-1268. doi:10.1016/S0140-6736(11)61452-9Schrauzer GN.Selenomethionine: a review of its nutritional significance, metabolism and toxicity.J Nutr. 2000;130(7):1653-1656. doi:10.1093/jn/130.7.1653
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Pirola I, Gandossi E, Agosti B, Delbarba A, Cappelli C.Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis.Endokrynol Pol. 2016;67(6):567-571. doi:10.5603/EP.2016.0064Kyrgios I, Giza S, Kotanidou EP, et al.l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.J Clin Pharm Ther. 2019;44(1):102-108. doi:10.1111/jcpt.12765Mantovani G, Isidori AM, Moretti C, et al.Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial.Endocrine. 2019;66(3):542-550. doi:10.1007/s12020-019-01958-1Shi Y, Yang W, Tang X, Yan Q, Cai X, Wu F.Keshan disease: a potentially fatal endemic cardiomyopathy in remote mountains of china.Front Pediatr. 2021;9:576916. doi: 10.3389/fped.2021.576916Lance P, Alberts DS, Thompson PA, et al.Colorectal adenomas in participants of the SELECT randomized trial of selenium and vitamin E for prostate cancer prevention.Cancer Prev Res (Phila). 2017;10(1):45-54. doi:10.1158/1940-6207.CAPR-16-0104Vinceti M, Filippini T, Del Giovane C, et al.Selenium for preventing cancer.Cochrane Database Syst Rev. 2018;1(1):CD005195. doi:10.1002/14651858.CD005195.pub4Benstoem C, Goetzenich A, Kraemer S, et al.Selenium and its supplementation in cardiovascular disease–what do we know?.Nutrients. 2015;7(5):3094-3118. doi:10.3390/nu7053094Robberecht H, De Bruyne T, Davioud-Charvet E, Mackrill J, Hermans N.Selenium status in elderly people: Longevity and age-related diseases.Curr Pharm Des. 2019;25(15):1694-1706. doi:10.2174/1381612825666190701144709Loef M, Schrauzer GN, Walach H.Selenium and Alzheimer’s disease: A systematic review.J Alzheimers Dis. 2011;26(1):81-104. doi:10.3233/JAD-2011-110414National Institute of Diabetes and Digestive and Kidney Diseases.Ulcerative colitis.Khazdouz M, Daryani NE, Cheraghpour M, et al.The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr. 2023 Dec;62(8):3125-3134. doi: 10.1007/s00394-023-03214-9National Institutes of Health Office of Dietary Supplements.Selenium.International Joint Commission Health Professionals Advisory Board.Selenosis.Donaldson M, Touger-Decker R.Vitamin and mineral supplements: friend or foe when combined with medications?J Am Dent Assoc. 2014 Nov;145(11):1153-8. doi: 10.14219/jada.2014.78Debski B, Milner JA.Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem. 2004 Sep;15(9):548-53. doi: 10.1016/j.jnutbio.2004.04.002Nordio M, Basciani S.Treatment with myo-inositol and selenium ensures euthyroidism in patients with autoimmune thyroiditis.Int J Endocrinol. 2017;2017:2549491. doi:10.1155/2017/2549491U.S. Department of Agriculture FoodData Central.Mollusks, oyster, pacific, raw.U.S. Department of Agriculture FoodData Central.Pasta, cooked, enriched, no salt added.U.S. Department of Agriculture FoodData Central.Fish, salmon, sockeye, cooked, dry heat.U.S. Department of Agriculture FoodData Central.Mollusks, clams, mixed species, raw.U.S. Department of Agriculture FoodData Central.Bread, pita, white, enriched.U.S. Department of Agriculture FoodData Central.Bread, raisin, enriched.U.S. Department of Agriculture FoodData Central.Cereals ready-to-eat, Ralston enriched wheat bran flakes.
Pirola I, Gandossi E, Agosti B, Delbarba A, Cappelli C.Selenium supplementation could restore euthyroidism in subclinical hypothyroid patients with autoimmune thyroiditis.Endokrynol Pol. 2016;67(6):567-571. doi:10.5603/EP.2016.0064
Kyrgios I, Giza S, Kotanidou EP, et al.l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.J Clin Pharm Ther. 2019;44(1):102-108. doi:10.1111/jcpt.12765
Mantovani G, Isidori AM, Moretti C, et al.Selenium supplementation in the management of thyroid autoimmunity during pregnancy: results of the “SERENA study”, a randomized, double-blind, placebo-controlled trial.Endocrine. 2019;66(3):542-550. doi:10.1007/s12020-019-01958-1
Shi Y, Yang W, Tang X, Yan Q, Cai X, Wu F.Keshan disease: a potentially fatal endemic cardiomyopathy in remote mountains of china.Front Pediatr. 2021;9:576916. doi: 10.3389/fped.2021.576916
Lance P, Alberts DS, Thompson PA, et al.Colorectal adenomas in participants of the SELECT randomized trial of selenium and vitamin E for prostate cancer prevention.Cancer Prev Res (Phila). 2017;10(1):45-54. doi:10.1158/1940-6207.CAPR-16-0104
Vinceti M, Filippini T, Del Giovane C, et al.Selenium for preventing cancer.Cochrane Database Syst Rev. 2018;1(1):CD005195. doi:10.1002/14651858.CD005195.pub4
Benstoem C, Goetzenich A, Kraemer S, et al.Selenium and its supplementation in cardiovascular disease–what do we know?.Nutrients. 2015;7(5):3094-3118. doi:10.3390/nu7053094
Robberecht H, De Bruyne T, Davioud-Charvet E, Mackrill J, Hermans N.Selenium status in elderly people: Longevity and age-related diseases.Curr Pharm Des. 2019;25(15):1694-1706. doi:10.2174/1381612825666190701144709
Loef M, Schrauzer GN, Walach H.Selenium and Alzheimer’s disease: A systematic review.J Alzheimers Dis. 2011;26(1):81-104. doi:10.3233/JAD-2011-110414
National Institute of Diabetes and Digestive and Kidney Diseases.Ulcerative colitis.
Khazdouz M, Daryani NE, Cheraghpour M, et al.The effect of selenium supplementation on disease activity and immune-inflammatory biomarkers in patients with mild-to-moderate ulcerative colitis: a randomized, double-blind, placebo-controlled clinical trial. Eur J Nutr. 2023 Dec;62(8):3125-3134. doi: 10.1007/s00394-023-03214-9
National Institutes of Health Office of Dietary Supplements.Selenium.
International Joint Commission Health Professionals Advisory Board.Selenosis.
Donaldson M, Touger-Decker R.Vitamin and mineral supplements: friend or foe when combined with medications?J Am Dent Assoc. 2014 Nov;145(11):1153-8. doi: 10.14219/jada.2014.78
Debski B, Milner JA.Dietary selenium supplementation prolongs pentobarbital induced hypnosis. J Nutr Biochem. 2004 Sep;15(9):548-53. doi: 10.1016/j.jnutbio.2004.04.002
Nordio M, Basciani S.Treatment with myo-inositol and selenium ensures euthyroidism in patients with autoimmune thyroiditis.Int J Endocrinol. 2017;2017:2549491. doi:10.1155/2017/2549491
U.S. Department of Agriculture FoodData Central.Mollusks, oyster, pacific, raw.
U.S. Department of Agriculture FoodData Central.Pasta, cooked, enriched, no salt added.
U.S. Department of Agriculture FoodData Central.Fish, salmon, sockeye, cooked, dry heat.
U.S. Department of Agriculture FoodData Central.Mollusks, clams, mixed species, raw.
U.S. Department of Agriculture FoodData Central.Bread, pita, white, enriched.
U.S. Department of Agriculture FoodData Central.Bread, raisin, enriched.
U.S. Department of Agriculture FoodData Central.Cereals ready-to-eat, Ralston enriched wheat bran flakes.
National Center for Biotechnology Information.PubChem compound summary for CID 15103, selenomethionine.Rayman MP.Selenium and human health.The Lancet. 2012;379(9822):1256-1268. doi:10.1016/S0140-6736(11)61452-9Schrauzer GN.Selenomethionine: a review of its nutritional significance, metabolism and toxicity.J Nutr. 2000;130(7):1653-1656. doi:10.1093/jn/130.7.1653
National Center for Biotechnology Information.PubChem compound summary for CID 15103, selenomethionine.
Rayman MP.Selenium and human health.The Lancet. 2012;379(9822):1256-1268. doi:10.1016/S0140-6736(11)61452-9
Schrauzer GN.Selenomethionine: a review of its nutritional significance, metabolism and toxicity.J Nutr. 2000;130(7):1653-1656. doi:10.1093/jn/130.7.1653
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