Table of ContentsView AllTable of ContentsParasite InfectionSymptomsDoes It Work?Herbs and SupplementsDiet ChangesSafetyWhen to Seek CareMedical Treatments
Table of ContentsView All
View All
Table of Contents
Parasite Infection
Symptoms
Does It Work?
Herbs and Supplements
Diet Changes
Safety
When to Seek Care
Medical Treatments
A parasite cleanse is a combination of herbal supplements and dietary changes aimed at killing and eliminating harmful organisms living in and feeding off your body.
Before relying on a parasite cleanse, it’s important to talk with a healthcare provider about proper treatment, as home remedies are often ineffective. People who diagnose themselves with aparasitemay be missing another cause for their symptoms. Meanwhile, those who do have a parasite may need more aggressive treatments than supplements and a new diet.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
What Is a Parasite Cleanse?
A parasite cleanse is intended to detoxify the body and treat intestinal parasites through a combination of herbal supplements and dietary changes (which include the addition of foods, vitamins, minerals, and probiotics to your diet).
Many of the natural remedies involved in a parasite cleanse may have general benefits (which may include aiding good gut health). However, evidence is limited as to whether they can actually cure a parasite infection on their own.
Causes of Parasitic InfectionsParasites can be picked up from pets (including dogs and cats), contaminated food, water, or feces, infected blood, and insects.Your risk of having a parasite is higher if youlive in or visit an area where parasites are common or where human or animal waste is not treated properly.Childcare and long-term care facilities are places where there’s a greater risk of parasites. The risk is also higher if you don’t useproper hygieneor you have an impaired immune system.
Causes of Parasitic Infections
Parasites can be picked up from pets (including dogs and cats), contaminated food, water, or feces, infected blood, and insects.Your risk of having a parasite is higher if youlive in or visit an area where parasites are common or where human or animal waste is not treated properly.Childcare and long-term care facilities are places where there’s a greater risk of parasites. The risk is also higher if you don’t useproper hygieneor you have an impaired immune system.
Parasites can be picked up from pets (including dogs and cats), contaminated food, water, or feces, infected blood, and insects.Your risk of having a parasite is higher if youlive in or visit an area where parasites are common or where human or animal waste is not treated properly.
Childcare and long-term care facilities are places where there’s a greater risk of parasites. The risk is also higher if you don’t useproper hygieneor you have an impaired immune system.
Symptoms of a Parasite Infection
The symptoms of a parasite infection will depend on the parasite and its location.Intestinal parasites can cause:
Although it’s rare, some parasites can enter other parts of the body, infecting the lungs, bladder, eyes, ears, and nervous system, including the brain.In severe cases, they may cause chronic illness or death.
Thinking you have symptoms of a parasite infection or even being worried about acquiring one may lead to you consider a parasite cleanse. It may be a popular fad diet online promoted online for treatment, but does it really work?
There’s not a whole lot of good evidence to back up the benefits of a parasite cleanse, or any cleanse for that matter. Before making any major changes to your diet, talk to your healthcare provider.What’s best for someone else may not be the same as what’s best for you.
Even taking certain supplements could help you feel better if you have a deficiency, although use should be discussed with a healthcare provider.
Herbs and Supplements in a Parasite Cleanse
Natural health practitioners recommend a range of different herbs and supplements for parasite cleanses. However, there’s no good evidence for their use and can have unintended side effects.
Certain herbs may have compounds that can be turned into plant-based drugs to treat parasites and cleanse the system of them.
But overall, there is limited research suggesting that herbs can help cleanse parasites if you’re already infected. More research is needed to confirm that any natural remedies can get rid of a parasite effectively.
Berberine
This chemical compound can be found in herbs such as theEuropean barberry(Berberis vulgaris).Berberinemay be able to decrease parasites.
Berberine’s history in treating intestinal parasites goes back to ancient China, where it was also used to treat other diseases, like diabetes. Berberine has antiprotozoal properties, meaning it can kill or inhibit the growth of protozoa.
You can find berberine in herbs likegoldenseal, goldthread, Oregon grape, phellodendron, and tree turmeric.
Berberine can cause interactions with other medications, herbs, and supplements, and is not safe for pregnant and breastfeeding people and newborns. Talk to your healthcare provider before taking berberine to make sure it’s right for you. Don’t use berberine if you’re taking cyclosporine (an immunosuppressive drug).
Papaya Seeds
In one 2015 clinical trial, a group of school children in one county in Kenya ate porridge with groundpapayaseeds in it for several months. Other groups were given porridge with an anti-parasitic medication added or plain porridge.
The group that ate papaya seed porridge had 63.9% fewer roundworm eggs in their stool after the test. The group that ate medicated porridge had 78.8% fewer eggs. The students who ate untreated porridge had higher egg counts overall.
Pumpkin Seeds
Pumpkinseeds are high in amino acids and fatty acids. In particular, they are rich in berberine, cucurbitine, and palmatine. All of these are amino acids known to damage certain parasites.
The amino acid content may be enough to kill intestinal parasites like tapeworms and roundworms, although one should not rely on this research alone. Pumpkin also contains nutrients that have antifungal and antimicrobial properties.
Wormwood
Wormwoodhas long been used in herbal medicine to treat a number of gastrointestinal ailments. While there is some evidence of its ability to fight off protozoa and helminths, most of the studies have been done on animals and can’t be applied to humans.
Many medications are made from compounds in the sweet wormwood plant.Still, more research is needed before it’s clear that the plant itself is a reliable way to treat infections.
People should make sure wormwood and products with wormwood are labeled as thujone-free, which means they contain less than a regulated about of thujone (a psychoactive chemical that can be toxic). Children, those pregnant or breastfeeding, or people with certain health conditions should steer clear of wormwood altogether.
Animal studies aren’t always representative of results in humans. However, they can help researchers determine if a specific line of research would be worth pursuing in human trials, and sometimes the results do line up.
Propolis
A 2021 review of studies called the anti-parasitic properties of propolis “promising,” especially against certain kinds of protozoa parasites and parasitic worms.
Probiotics
A 2018 paper concluded thatprobioticscan help decrease the risk of getting a parasite. The authors also noted that probiotics may be helpful as a complementary therapy for people who have gastrointestinal parasites.
Probiotics are microorganisms that can help support the natural community of bacteria in your digestive system.
Vitamins and Minerals
There is evidence that a diet rich in vitamin A and the mineralsseleniumandzincmay improve your body’s natural defense against parasite infection.
Vitamin A has many other beneficial properties. It helps keep your teeth, bones, soft tissue, mucous membranes, and skin healthy. It also helps with eyesight, especially in low light.
Selenium and zinc are important micronutrients that help boost the immune system.
Parasite Cleanse Diet Changes
Natural medicine experts say stomach acid may help to protect you from parasites in food. They recommend that you:
Some natural medicine providers also suggest a gut cleanse or detox. This involves pairing a high-fiber diet with supplements to clear out your intestines. These supplements includepsyllium, beetroot, andflaxseeds.
Right now, there isn’t much evidence to suggest that your diet, cleanses, or detoxes can prevent or treat a parasite infection.
1:41Click Play to Learn More About Tapeworm Home Remedies
1:41
Click Play to Learn More About Tapeworm Home Remedies
Safety Concerns
Using a parasite cleanse without first talking to your healthcare provider can be unsafe.
If you do have a parasite, the cleanse alone may not be enough to eliminate it. A parasitic infection that goes untreated (or that is insufficiently treated) may have serious long-term consequences, such as:
Some products contain illegal and potentially harmful ingredients.Do your research on the product before making a purchase.
Dietary supplements may cause uncomfortable side effects, such as:
Consult a healthcare provider before adding any herbal supplements to your diet, including the ones found in parasite cleanses. People who are pregnant or nursing, children, and those with certain health conditions or taking certain medications should especially avoid supplements until talking to a healthcare provider.
How to Do a Detox Cleanse At Home
When to See a Healthcare Provider
If you’ve been traveling in a place where parasites are common and you have symptoms of infection, it’s possible (though unlikely) that you might have a parasitic infection. If you have symptoms, see a healthcare provider right away.
Healthcare providers may order tests (includingstool tests) to identify the parasite. They’ll also prescribe treatments and explain how to keep the problem from coming back.
If you’re still interested in remedies that are part of parasite cleanses, talk to your healthcare provider about what’s best for you.
After treatment, you may need a fecal test to be sure the parasites are gone.
Verywell / Nusha Ashjaee

How a Tapeworm Infection Is Diagnosed
Other Treatments for Parasite Infections
Which treatment the healthcare provider recommends depends on the type of parasitic infection. The results of tests like stool tests help guide healthcare providers in making a decision.
Some antiparasitic drugs like ivermectin come in different forms. For example, ivermectin in tablet form can be used to treat some parasitic worms, while topical formulations like creams are used forhead liceand certain skin conditions.
Summary
If you’re thinking about adding a natural remedy or parasite cleanse to your treatment plan, be aware that the research supporting their use is thin.
The extracts of berberine and wormwood may be useful. Pumpkin seeds and papaya seeds have also reduced parasite numbers in humans. A healthy diet including vitamin A, selenium, zinc, and probiotics may help you build up your immune defenses. Still more evidence is needed as to whether these are effective remedies on their own and, with some, unintended side effects are possible.
Talk to your healthcare provider before adding any herbs or supplements to your diet. In some cases, medical treatment may be necessary for parasitic infection.
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Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Mount Sinai.Intestinal parasites.Centers for Disease Control and Prevention.What causes parasitic diseases.Centers for Disease Control and Prevention.AboutGiardia.Centers for Disease Control and Prevention.About gnathostomiasis.Medline PLus.Ova and parasite test.Hechenbleikner EM, McQuade JA.Parasitic colitis.Clin Colon Rectal Surg. 2015;28(2):79-86. doi:10.1055/s-0035-1547335Centers for Disease Control and Prevention.About toxoplasmosis.National Center for Complementary and Integrative Health.“Detoxes” and “cleanses”: what you need to know.Academy of Nutrition and Dietetics.What’s the deal with detox diets?Neag MA, Mocan A, Echeverría J, et al.Berberine: Botanical occurrence, traditional uses, extraction methods, and relevance in cardiovascular, metabolic, hepatic, and renal disorders.Front Pharmacol. 2018;9:557. doi:10.3389/fphar.2018.00557MedlinePlus.Berberine.Kugo M, Keter L, Maiyo A, et al.Fortification of Carica papaya fruit seeds to school meal snacks may aid Africa mass deworming programs: a preliminary survey.BMC Complement Altern Med. 2018;18(1):327. doi:10.1186/s12906-018-2379-2Johnston CJ, Robertson E, Harcus Y, et al.Cultivation ofHeligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products.J Vis Exp. 2015;(98):e52412. doi:10.3791/52412Hussain A, Kausar T, Sehar S, et al.A review on biochemical constituents of pumpkin and their role as pharma foods; a key strategy to improve health in post COVID 19 period.Food Prod Process and Nutr. 2023;5(1):22. doi:10.1186/s43014-023-00138-zBatiha GES, Olatunde A, El-Mleeh, et al.Bioactive compounds, pharmacological actions, and pharmacokinetics of wormwood (Artemisia absinthium).Antibiotics (Basel). 2020;9(6):353. doi:10.3390/antibiotics9060353Loo CS, Lam NS, Yu D, Su XZ, Lu F.Artemisinin and its derivatives in treating protozoan infections beyond malaria.Pharmacol Res. 2017;117:192-217. doi:10.1016/j.phrs.2016.11.012De L. Paula LA, Cândido AC, Santos MF, et al.Antiparasitic properties of propolis extracts and their compounds.Chem Biodivers. 2021;18(9):e2100310. doi:10.1002/cbdv.202100310Ajanya BU, Attah F, Mahmud ME, et al.Therapeutic potency of probiotics in the treatment of gastrointestinal parasites.J Publ Health Dent.2018;1(2):22-30. doi:10.31248/JPHD2018.011Shea-Donohue T, Qin B, Smith A.Parasites, nutrition, immune responses and biology of metabolic tissues.Parasite Immunol. 2017;39(5):10.1111/pim.12422. doi:10.1111/pim.12422MedlinePlus.Vitamin A.SeyedAlinaghi SA, Shahidi R, Mojdeganlou H, et al.The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.J Health Popul Nutr. 2024;43(1):16. doi:10.1186/s41043-024-00504-8Lepczyńska M, Białkowska J, Dzika E, Piskorz-Ogórek K, Korycińska J.Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity?Eur J Clin Microbiol Infect Dis.2017;36(9):1531-1540. doi:10.1007/s10096-017-2965-0Reda AA.Probiotics for the control of helminth zoonosis.J Vet Med. 2018;2018:4178986. doi:10.1155/2018/4178986Sepsis Alliance.Parasitic infections.UC Davis Health.Parasitic infections.National Institutes of Health. Office of Dietary Supplements.Dietary supplements: what you need to know.Centers for Disease Control and Prevention.What to do when you think you have a parasitic disease.National Library of Medicine.Antiparasitic drugs.American Medical Association.What is ivermectin?Additional ReadingMahmoudvand H, Saedi Dezaki E, Sharififar F, Ezatpour B, Jahanbakhsh S, Fasihi Harandi M.Protoscolecidal effect ofBerberis vulgarisroot extract and its main compound, berberine in cystic echinococcosis.Iran J Parasitol. 2014;9(4):503-10.Rouhani S, Salehi N, Kamalinejad M, Zayeri F.Efficacy ofBerberis vulgarisaqueous extract on viability of echinococcus granulosus protoscolices.J Invest Surg.2013;26(6):347-51. doi.org/10.3109/08941939.2013.818746
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Mount Sinai.Intestinal parasites.Centers for Disease Control and Prevention.What causes parasitic diseases.Centers for Disease Control and Prevention.AboutGiardia.Centers for Disease Control and Prevention.About gnathostomiasis.Medline PLus.Ova and parasite test.Hechenbleikner EM, McQuade JA.Parasitic colitis.Clin Colon Rectal Surg. 2015;28(2):79-86. doi:10.1055/s-0035-1547335Centers for Disease Control and Prevention.About toxoplasmosis.National Center for Complementary and Integrative Health.“Detoxes” and “cleanses”: what you need to know.Academy of Nutrition and Dietetics.What’s the deal with detox diets?Neag MA, Mocan A, Echeverría J, et al.Berberine: Botanical occurrence, traditional uses, extraction methods, and relevance in cardiovascular, metabolic, hepatic, and renal disorders.Front Pharmacol. 2018;9:557. doi:10.3389/fphar.2018.00557MedlinePlus.Berberine.Kugo M, Keter L, Maiyo A, et al.Fortification of Carica papaya fruit seeds to school meal snacks may aid Africa mass deworming programs: a preliminary survey.BMC Complement Altern Med. 2018;18(1):327. doi:10.1186/s12906-018-2379-2Johnston CJ, Robertson E, Harcus Y, et al.Cultivation ofHeligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products.J Vis Exp. 2015;(98):e52412. doi:10.3791/52412Hussain A, Kausar T, Sehar S, et al.A review on biochemical constituents of pumpkin and their role as pharma foods; a key strategy to improve health in post COVID 19 period.Food Prod Process and Nutr. 2023;5(1):22. doi:10.1186/s43014-023-00138-zBatiha GES, Olatunde A, El-Mleeh, et al.Bioactive compounds, pharmacological actions, and pharmacokinetics of wormwood (Artemisia absinthium).Antibiotics (Basel). 2020;9(6):353. doi:10.3390/antibiotics9060353Loo CS, Lam NS, Yu D, Su XZ, Lu F.Artemisinin and its derivatives in treating protozoan infections beyond malaria.Pharmacol Res. 2017;117:192-217. doi:10.1016/j.phrs.2016.11.012De L. Paula LA, Cândido AC, Santos MF, et al.Antiparasitic properties of propolis extracts and their compounds.Chem Biodivers. 2021;18(9):e2100310. doi:10.1002/cbdv.202100310Ajanya BU, Attah F, Mahmud ME, et al.Therapeutic potency of probiotics in the treatment of gastrointestinal parasites.J Publ Health Dent.2018;1(2):22-30. doi:10.31248/JPHD2018.011Shea-Donohue T, Qin B, Smith A.Parasites, nutrition, immune responses and biology of metabolic tissues.Parasite Immunol. 2017;39(5):10.1111/pim.12422. doi:10.1111/pim.12422MedlinePlus.Vitamin A.SeyedAlinaghi SA, Shahidi R, Mojdeganlou H, et al.The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.J Health Popul Nutr. 2024;43(1):16. doi:10.1186/s41043-024-00504-8Lepczyńska M, Białkowska J, Dzika E, Piskorz-Ogórek K, Korycińska J.Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity?Eur J Clin Microbiol Infect Dis.2017;36(9):1531-1540. doi:10.1007/s10096-017-2965-0Reda AA.Probiotics for the control of helminth zoonosis.J Vet Med. 2018;2018:4178986. doi:10.1155/2018/4178986Sepsis Alliance.Parasitic infections.UC Davis Health.Parasitic infections.National Institutes of Health. Office of Dietary Supplements.Dietary supplements: what you need to know.Centers for Disease Control and Prevention.What to do when you think you have a parasitic disease.National Library of Medicine.Antiparasitic drugs.American Medical Association.What is ivermectin?
Mount Sinai.Intestinal parasites.
Centers for Disease Control and Prevention.What causes parasitic diseases.
Centers for Disease Control and Prevention.AboutGiardia.
Centers for Disease Control and Prevention.About gnathostomiasis.
Medline PLus.Ova and parasite test.
Hechenbleikner EM, McQuade JA.Parasitic colitis.Clin Colon Rectal Surg. 2015;28(2):79-86. doi:10.1055/s-0035-1547335
Centers for Disease Control and Prevention.About toxoplasmosis.
National Center for Complementary and Integrative Health.“Detoxes” and “cleanses”: what you need to know.
Academy of Nutrition and Dietetics.What’s the deal with detox diets?
Neag MA, Mocan A, Echeverría J, et al.Berberine: Botanical occurrence, traditional uses, extraction methods, and relevance in cardiovascular, metabolic, hepatic, and renal disorders.Front Pharmacol. 2018;9:557. doi:10.3389/fphar.2018.00557
MedlinePlus.Berberine.
Kugo M, Keter L, Maiyo A, et al.Fortification of Carica papaya fruit seeds to school meal snacks may aid Africa mass deworming programs: a preliminary survey.BMC Complement Altern Med. 2018;18(1):327. doi:10.1186/s12906-018-2379-2
Johnston CJ, Robertson E, Harcus Y, et al.Cultivation ofHeligmosomoides polygyrus: an immunomodulatory nematode parasite and its secreted products.J Vis Exp. 2015;(98):e52412. doi:10.3791/52412
Hussain A, Kausar T, Sehar S, et al.A review on biochemical constituents of pumpkin and their role as pharma foods; a key strategy to improve health in post COVID 19 period.Food Prod Process and Nutr. 2023;5(1):22. doi:10.1186/s43014-023-00138-z
Batiha GES, Olatunde A, El-Mleeh, et al.Bioactive compounds, pharmacological actions, and pharmacokinetics of wormwood (Artemisia absinthium).Antibiotics (Basel). 2020;9(6):353. doi:10.3390/antibiotics9060353
Loo CS, Lam NS, Yu D, Su XZ, Lu F.Artemisinin and its derivatives in treating protozoan infections beyond malaria.Pharmacol Res. 2017;117:192-217. doi:10.1016/j.phrs.2016.11.012
De L. Paula LA, Cândido AC, Santos MF, et al.Antiparasitic properties of propolis extracts and their compounds.Chem Biodivers. 2021;18(9):e2100310. doi:10.1002/cbdv.202100310
Ajanya BU, Attah F, Mahmud ME, et al.Therapeutic potency of probiotics in the treatment of gastrointestinal parasites.J Publ Health Dent.2018;1(2):22-30. doi:10.31248/JPHD2018.011
Shea-Donohue T, Qin B, Smith A.Parasites, nutrition, immune responses and biology of metabolic tissues.Parasite Immunol. 2017;39(5):10.1111/pim.12422. doi:10.1111/pim.12422
MedlinePlus.Vitamin A.
SeyedAlinaghi SA, Shahidi R, Mojdeganlou H, et al.The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review.J Health Popul Nutr. 2024;43(1):16. doi:10.1186/s41043-024-00504-8
Lepczyńska M, Białkowska J, Dzika E, Piskorz-Ogórek K, Korycińska J.Blastocystis: how do specific diets and human gut microbiota affect its development and pathogenicity?Eur J Clin Microbiol Infect Dis.2017;36(9):1531-1540. doi:10.1007/s10096-017-2965-0
Reda AA.Probiotics for the control of helminth zoonosis.J Vet Med. 2018;2018:4178986. doi:10.1155/2018/4178986
Sepsis Alliance.Parasitic infections.
UC Davis Health.Parasitic infections.
National Institutes of Health. Office of Dietary Supplements.Dietary supplements: what you need to know.
Centers for Disease Control and Prevention.What to do when you think you have a parasitic disease.
National Library of Medicine.Antiparasitic drugs.
American Medical Association.What is ivermectin?
Mahmoudvand H, Saedi Dezaki E, Sharififar F, Ezatpour B, Jahanbakhsh S, Fasihi Harandi M.Protoscolecidal effect ofBerberis vulgarisroot extract and its main compound, berberine in cystic echinococcosis.Iran J Parasitol. 2014;9(4):503-10.Rouhani S, Salehi N, Kamalinejad M, Zayeri F.Efficacy ofBerberis vulgarisaqueous extract on viability of echinococcus granulosus protoscolices.J Invest Surg.2013;26(6):347-51. doi.org/10.3109/08941939.2013.818746
Mahmoudvand H, Saedi Dezaki E, Sharififar F, Ezatpour B, Jahanbakhsh S, Fasihi Harandi M.Protoscolecidal effect ofBerberis vulgarisroot extract and its main compound, berberine in cystic echinococcosis.Iran J Parasitol. 2014;9(4):503-10.
Rouhani S, Salehi N, Kamalinejad M, Zayeri F.Efficacy ofBerberis vulgarisaqueous extract on viability of echinococcus granulosus protoscolices.J Invest Surg.2013;26(6):347-51. doi.org/10.3109/08941939.2013.818746
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