Table of ContentsView AllTable of ContentsUsesSide EffectsPrecautionsDosageToxicityInteractionsHow to StoreSimilar SupplementsFAQsSources & What to Look For
Table of ContentsView All
View All
Table of Contents
Uses
Side Effects
Precautions
Dosage
Toxicity
Interactions
How to Store
Similar Supplements
FAQs
Sources & What to Look For
Estroven is the brand name of a line of dietary supplements that contains a combination of herbal extracts, soy isoflavones, vitamins, and minerals. Since 1997, Estroven products have been advertised as having the ability to ease some of the most frequently experiencedsymptoms of menopause.
Three main ingredients are found in all Estroven products:black cohosh, soyisoflavones, and rhapontic rhubarb extract.
This article discusses menopause and its symptoms. It explains how Estroven products may help people during menopause and Estroven’s possible side effects.
Estroven/i-Health.
Supplements FactsActive ingredients(s): Black cohosh, soy isoflavones, Rhapontic Rhubarb (ERr 731)Alternate name(s): Estroven Maximum Strength, Estroven Complete Multi-Symptom Menopause ReliefLegal status: SupplementSuggested dose: Suggested dosages listed on each product package for different formulationsSafety considerations: Allergies,pregnancy,breastfeeding,and liver disorders
Supplements Facts
Active ingredients(s): Black cohosh, soy isoflavones, Rhapontic Rhubarb (ERr 731)Alternate name(s): Estroven Maximum Strength, Estroven Complete Multi-Symptom Menopause ReliefLegal status: SupplementSuggested dose: Suggested dosages listed on each product package for different formulationsSafety considerations: Allergies,pregnancy,breastfeeding,and liver disorders
Verywell / Gary Ferster
Uses of Estroven
Menopause
Twelve months after the final menstrual period, which occurs in people designated female at birth around age 45 to 55, the next part of the reproductive life cycle, calledmenopause, begins. Estroven is typically used for symptoms of menopause. Symptoms may include hot flashes, vaginal dryness, emotional symptoms, andsleep changes.
Menopause symptoms are sometimes treated withhormone replacement therapy(HRT). Clinical studies about the effects of black cohosh on menopause symptoms have shown mixed results.
Soy isoflavones, another component found in Estroven, have also been believed to relieve menopause symptoms. Some clinical data suggest that soy isoflavones reduced menopausal symptoms such as hot flashes, bone health, and lipids.This data is not enough to identify who would benefit from the use of soy isoflavones.
More research is needed to determine if these supplements are safe and effective for treating menopause.
What Are the Side Effects of Estroven?
Information about the side effects of Estroven as a combination product is lacking in clinical study data. There are some known side effects of black cohosh and soy isoflavones, components (ingredients) of Estroven.
Common Side Effects
Most side effects of products containing black cohosh are mild. Black cohosh side effects include:
Potential soy side effects include:
Severe Side Effects
There are no reported severe side effects of Estroven. However, there are instances in which black cohosh may have caused liver damage.These cases are rare, and it cannot be sure that black cohosh alone caused the liver disorder.
If you are taking prescription medications or receiving care for a disease, such as chemotherapy for cancer, tell your healthcare provider before taking this or any other herbal supplement.
Because Estroven contains black cohosh, there are precautions to be aware of when using Estroven as a supplement.
Anyone who has an allergy to the ingredients of Estroven should not use it.
The U.S. Pharmacopeia, a nonprofit scientific organization that vets supplements, recommends that people with diseases or conditions affecting the liver ask their healthcare provider before taking any supplements that have black cohosh in them.
Use caution with Estroven if you take certain medications like blood-thinners, thyroid medicines,or monoamine oxidase inhibitors (MAOIs).
Dosage: How Much Estroven Should I Take?
Always speak with a healthcare provider before taking a supplement to ensure that the supplement and dosage are appropriate for your individual needs.
Estroven is a dietary supplement that comes in the form of a capsule or caplet. It can be taken daily with or without food. The best time to take Estroven is with a meal; food may help you to avoid mild stomach upset.
Estroven products do not require a prescription and are available over the counter at most pharmacies and major retailers throughout the United States. The products can also be purchased online.
What Happens If I Take Too Much Estroven?
Using Estroven as recommended on the product packaging is the safest way to use this supplement. There are no data on the effects of higher doses than suggested.
The effects of high doses of Estroven are unknown and should be avoided.
Estroven comprises many substances that may interact with other supplements, herbs, and medications. Reviewing the use of Estroven with your healthcare provider is best.
Blood-thinning medications: Estroven may interact with blood-thinning medications such as Jantoven (warfarin).
MAOIs: The soy isoflavones in some Estroven formulations may interact with monoamine oxidase inhibitors.
Thyroid medications: Estroven may interact with thyroid medications such as Synthroid (levothyroxine).
It is essential to read a supplement’s ingredient list and nutrition facts panel carefully to know which ingredients and how much of each component is included. Review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications.
How to Store Estroven
When storing Estroven it is best to follow the package recommendations. Storage and disposal instructions should be provided on the product packaging.
In general, it is safe to store supplements in a cool, dry, dark place. Keep Estroven and all supplements and medications out of the reach of children and pets.
There are other supplements available that tout menopausal symptom relief. Just as Estroven these supplements are a formulation of several products.
There are a few herbs that have been studied for their effects on menopause symptoms, such as:
Supplements that contain these herbs or a combination of these and other products are used for the relief of menopausal symptoms. Examples of such supplements are:
Pueraria Mirifica: An Herb for Menopause Support?
Frequently Asked Questions
Yes. Some products used to treat menopause symptoms include evening primrose oil, red clover, and flaxseed. In most cases, the research is mixed on how effective they are. It’s a good idea to talk to your healthcare provider about taking them.Learn MoreSupplements That Can Help Manage Menopause Symptoms
Yes. Some products used to treat menopause symptoms include evening primrose oil, red clover, and flaxseed. In most cases, the research is mixed on how effective they are. It’s a good idea to talk to your healthcare provider about taking them.
Learn MoreSupplements That Can Help Manage Menopause Symptoms
Probably not. All Estroven products but one contain soy isoflavones that could provoke a reaction in people with soy allergies or sensitivities. Talk to your healthcare provider before taking any Estroven product if you’re allergic to soy.Learn MoreOverview of Soy Allergy
Probably not. All Estroven products but one contain soy isoflavones that could provoke a reaction in people with soy allergies or sensitivities. Talk to your healthcare provider before taking any Estroven product if you’re allergic to soy.
Learn MoreOverview of Soy Allergy
Learn MoreThe Role of Estrogen in Your Body
Sources of Estroven & What to Look For
Estroven is a readily available supplement used for the relief of menopausal symptoms. It can be found in drugstores, and grocery stores, and it is available online.
Estroven Supplements
The Estroven line of supplements contains products of differing strengths and formulations. These supplements are available in caplet or capsule form.
Summary
Some supplements, including Estroven products, are designed to relieve menopause symptoms. They contain black cohosh root and other ingredients, depending on the formula.
These supplements may ease symptoms, such as night sweats or mood swings, but the benefits remain unproven. There is not enough data to confirm they are safe or effective.
Estroven products, and especially their black cohosh and soy ingredients, also may cause side effects or possible drug interactions (ex., thyroid medicines, MAOIs, blood-thinning medications). Estroven should not be taken without guidance from a healthcare provider.
Hot flashes and other symptoms of menopause are common. Supplements like Estroven may help, but be sure you know what you’re taking and if it’s safe for you.
More Menopause Treatments
Correction - June 22, 2023: The article was updated to include rhaphontic rhubarb as a primary ingredient found in Estroven products.
11 SourcesVerywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Hajirahimkhan A, Dietz BM, Bolton JL.Botanical modulation of menopausal symptoms: mechanisms of action?Planta Med. 2013;79(7):538-553. doi:10.1055/s-0032-1328187Croden J, Ross S, Yuksel N, Sydora BC. Asurvey of the availability in Canadian pharmacy chains of over-the-counter natural health products for menopause symptoms.BMC Complement Altern Med. 2015;15:86.National Center for Complementary and Integrative Health.Black cohosh.Muqeet Adnan M, Khan M, Hashmi S, Hamza M, AbdulMujeeb S, Amer S.Black cohosh and liver toxicity: is there a relationship?Case Rep Gastrointest Med. 2014;2014:860614. doi:10.1155/2014/860614.Dohou J, Mouret-Reynier MA, Kwiatkowski F, et al.A retrospective study on the onset of menopause after chemotherapy: Analysis of data extracted from the Jean Perrin Comprehensive Cancer Center Database concerning 345 young breast cancer patients diagnosed between 1994 and 2012.Oncology. 2017;92(5):255-263. doi:10.1159/000455049Francene M Steinberg, Michael J Murray, Richard D Lewis, et al.Clinical outcomes of a 2-y soy isoflavone supplementation in menopausal women.The American Journal of Clinical Nutrition.2011;93(2): 356–367, doi.org/10.3945/ajcn.110.008359National Institutes of Health.Soy.American Association of Family Physicians.Soy: A Complete Source of Protein.National Institutes of Health Office of Dietary Supplements.Black Cohosh.Alliance for Clinical Trials in Oncology.Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes.Mohapatra S, Iqubal A, Ansari MJ, et al.Benefits of black cohosh (Cimicifuga racemosa) for women health: an up-close and in-depth review.Pharmaceuticals. 2022;15(3):278.Additional ReadingCancer Research UK.Black cohosh and cancer.U.S. Food and Drug Administration.Menopause and hormones: Common questions.
11 Sources
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.Hajirahimkhan A, Dietz BM, Bolton JL.Botanical modulation of menopausal symptoms: mechanisms of action?Planta Med. 2013;79(7):538-553. doi:10.1055/s-0032-1328187Croden J, Ross S, Yuksel N, Sydora BC. Asurvey of the availability in Canadian pharmacy chains of over-the-counter natural health products for menopause symptoms.BMC Complement Altern Med. 2015;15:86.National Center for Complementary and Integrative Health.Black cohosh.Muqeet Adnan M, Khan M, Hashmi S, Hamza M, AbdulMujeeb S, Amer S.Black cohosh and liver toxicity: is there a relationship?Case Rep Gastrointest Med. 2014;2014:860614. doi:10.1155/2014/860614.Dohou J, Mouret-Reynier MA, Kwiatkowski F, et al.A retrospective study on the onset of menopause after chemotherapy: Analysis of data extracted from the Jean Perrin Comprehensive Cancer Center Database concerning 345 young breast cancer patients diagnosed between 1994 and 2012.Oncology. 2017;92(5):255-263. doi:10.1159/000455049Francene M Steinberg, Michael J Murray, Richard D Lewis, et al.Clinical outcomes of a 2-y soy isoflavone supplementation in menopausal women.The American Journal of Clinical Nutrition.2011;93(2): 356–367, doi.org/10.3945/ajcn.110.008359National Institutes of Health.Soy.American Association of Family Physicians.Soy: A Complete Source of Protein.National Institutes of Health Office of Dietary Supplements.Black Cohosh.Alliance for Clinical Trials in Oncology.Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes.Mohapatra S, Iqubal A, Ansari MJ, et al.Benefits of black cohosh (Cimicifuga racemosa) for women health: an up-close and in-depth review.Pharmaceuticals. 2022;15(3):278.Additional ReadingCancer Research UK.Black cohosh and cancer.U.S. Food and Drug Administration.Menopause and hormones: Common questions.
Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
Hajirahimkhan A, Dietz BM, Bolton JL.Botanical modulation of menopausal symptoms: mechanisms of action?Planta Med. 2013;79(7):538-553. doi:10.1055/s-0032-1328187Croden J, Ross S, Yuksel N, Sydora BC. Asurvey of the availability in Canadian pharmacy chains of over-the-counter natural health products for menopause symptoms.BMC Complement Altern Med. 2015;15:86.National Center for Complementary and Integrative Health.Black cohosh.Muqeet Adnan M, Khan M, Hashmi S, Hamza M, AbdulMujeeb S, Amer S.Black cohosh and liver toxicity: is there a relationship?Case Rep Gastrointest Med. 2014;2014:860614. doi:10.1155/2014/860614.Dohou J, Mouret-Reynier MA, Kwiatkowski F, et al.A retrospective study on the onset of menopause after chemotherapy: Analysis of data extracted from the Jean Perrin Comprehensive Cancer Center Database concerning 345 young breast cancer patients diagnosed between 1994 and 2012.Oncology. 2017;92(5):255-263. doi:10.1159/000455049Francene M Steinberg, Michael J Murray, Richard D Lewis, et al.Clinical outcomes of a 2-y soy isoflavone supplementation in menopausal women.The American Journal of Clinical Nutrition.2011;93(2): 356–367, doi.org/10.3945/ajcn.110.008359National Institutes of Health.Soy.American Association of Family Physicians.Soy: A Complete Source of Protein.National Institutes of Health Office of Dietary Supplements.Black Cohosh.Alliance for Clinical Trials in Oncology.Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes.Mohapatra S, Iqubal A, Ansari MJ, et al.Benefits of black cohosh (Cimicifuga racemosa) for women health: an up-close and in-depth review.Pharmaceuticals. 2022;15(3):278.
Hajirahimkhan A, Dietz BM, Bolton JL.Botanical modulation of menopausal symptoms: mechanisms of action?Planta Med. 2013;79(7):538-553. doi:10.1055/s-0032-1328187
Croden J, Ross S, Yuksel N, Sydora BC. Asurvey of the availability in Canadian pharmacy chains of over-the-counter natural health products for menopause symptoms.BMC Complement Altern Med. 2015;15:86.
National Center for Complementary and Integrative Health.Black cohosh.
Muqeet Adnan M, Khan M, Hashmi S, Hamza M, AbdulMujeeb S, Amer S.Black cohosh and liver toxicity: is there a relationship?Case Rep Gastrointest Med. 2014;2014:860614. doi:10.1155/2014/860614.
Dohou J, Mouret-Reynier MA, Kwiatkowski F, et al.A retrospective study on the onset of menopause after chemotherapy: Analysis of data extracted from the Jean Perrin Comprehensive Cancer Center Database concerning 345 young breast cancer patients diagnosed between 1994 and 2012.Oncology. 2017;92(5):255-263. doi:10.1159/000455049
Francene M Steinberg, Michael J Murray, Richard D Lewis, et al.Clinical outcomes of a 2-y soy isoflavone supplementation in menopausal women.The American Journal of Clinical Nutrition.2011;93(2): 356–367, doi.org/10.3945/ajcn.110.008359
National Institutes of Health.Soy.
American Association of Family Physicians.Soy: A Complete Source of Protein.
National Institutes of Health Office of Dietary Supplements.Black Cohosh.
Alliance for Clinical Trials in Oncology.Phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes.
Mohapatra S, Iqubal A, Ansari MJ, et al.Benefits of black cohosh (Cimicifuga racemosa) for women health: an up-close and in-depth review.Pharmaceuticals. 2022;15(3):278.
Cancer Research UK.Black cohosh and cancer.U.S. Food and Drug Administration.Menopause and hormones: Common questions.
Cancer Research UK.Black cohosh and cancer.
U.S. Food and Drug Administration.Menopause and hormones: Common questions.
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