Table of ContentsView AllTable of ContentsUsesNutritionSide EffectsDosageSimilar Supplements
Table of ContentsView All
View All
Table of Contents
Uses
Nutrition
Side Effects
Dosage
Similar Supplements
Lecithin is a mixture of fats that have essential functions in human cells. It is found in various foods, including egg yolks, sunflower seeds, soybeans, and fish. Lecithin is sometimes added to skincare products, medications, andplacebosinrandomized controlled trials.
Lecithin benefits have been studied for treating and preventing certain health conditions, includingcognitive impairment,high cholesterol,menopause symptoms, andulcerative colitis. Although it has shown promise in some studies, more research is needed.
In the United States, the Food and Drug Administration (FDA) does not regulate supplements the way it regulates prescription drugs. That means some supplement products may not contain what the label says. Whenchoosing a supplement, look for independently tested products and consult a healthcare provider, registered dietitian nutritionist (RD or RDN), or pharmacist.
Function of Lecithin
Lecithin containsphospholipidslikephosphatidylcholine.Phospholipids are a type of fat combined withphosphate.Your body converts phosphatidylcholine intocholine. Choline supports cell structure in the following areas of your body:
Lecithin deficiency is rare and symptoms are most likely due to choline levels, not lecithin itself. These symptoms include:
The following highlights research conducted using lecithin for specific conditions. Keep in mind that no supplement is intended to treat, cure, or prevent disease. Don’t discontinue your prescription medication without first discussing with your healthcare provider how or when to use lecithin.
Dementia or Cognitive Impairment
Researchers have looked into lecithin’s effects on the following:
The results of the meta-analysis (collection of studies) suggested lecithin positively impacted self-reported memory issues. However, results for dementia treatment were unclear.
A review suggested that choline may be somewhat helpful for cognitive impairment from a head injury.The phosphatidylcholine in lecithin, in part, breaks down to choline. However, further research is warranted regarding lecithin’s specific effects.
High Cholesterol
Lecithin has been suggested to have anti-inflammatory andcardiovascular protective effects.
A small study found that 430 milligrams (mg) of soy lecithin daily significantly decreasedtotal cholesteroland triglycerides in adult male rats.Larger, well-designed studies are needed to confirm these results.
Mastitis
Mastitisis an inflammation of breast tissue. It can occur in breastfeeding people.Clogged milk ductscan lead to mastitis.
Some studies have found that lecithin may treat or prevent clogged milk ducts.One source recommended taking 5 to 10 grams (g) of soy or sunflower lecithin a day to reduce inflammation in the milk ducts.However, further study is needed.
Be sure to speak to a healthcare provider before using lecithin or other supplements during breastfeeding.
Menopausal Symptoms
Researchers used high (1,200 mg per day) or low doses (600 mg per day) of soy lecithin or placebo for eight weeks in people undergoing menopause.
The group taking the higher dosage reportedly experienced the following:
More research is needed to confirm these results.
Medication-Induced Tardive Dyskinesia
A number of older studies have examined the effects of lecithin on TD. However, there isn’t enough evidence to warrant further study of lecithin’s effectiveness against TD.
Digestion
Lecithin may stimulate mucus production in the intestine. This may aid digestion and help protect the lining of your gastrointestinal system.
Lecithin is sometimes suggested for people withirritable bowel syndrome (IBS). However, some limited research suggests that soy lecithin may increase the abundance of undesirable gut bacteria.
Larger, more well-designed studies are needed before lecithin can be recommended for digestion and IBS.
Ulcerative Colitis
Some individuals withulcerative colitishave low levels ofphosphatidylcholine(also found in lecithin). Ulcerative colitis is a type of inflammatory bowel disease (IBD) affecting the large intestine. Scientists have suggested phosphatidylcholine supplementation may protect the colon from “bad” bacteria and inflammation.A meta-analysis (collection of studies) suggested 30% phosphatidylcholine-containing lecithin improved outcomes in people with ulcerative colitis.While studies have suggested benefits, more research is needed to confirm these results.
Gallbladder Disease
Lecithin supplements are sometimes used to prevent and limitgallstones. Research among 148 people with gallbladder disease found 17% had used lecithin supplements, and 71% were open to using lecithin if a healthcare provider recommended it.
However, the research supporting this use is limited. More research must be done to understand if lecithin can help manage gallbladder disease.
Liver Disease
Research suggested phosphatidylcholine could help prevent or reducemetabolic dysfunction-associated steatotic liver disease(MASLD, formerly known as nonalcoholic fatty liver disease or NAFLD).
In MASLD, fat builds up in the liver. Over time, MASLD can lead to liver cirrhosis and liver failure.
Phosphatidylcholine is just one part of lecithin. And the research for phosphatidylcholine or lecithin in liver disease is very preliminary.More research is needed to confirm these results.
Wound Healing
Lecithin may help wounds heal faster. One animal study found that soy and egg lecithin’sfree radicalscavenging activities could help speed wound healing.
However, that evidence is insufficient as effects in animal studies don’t necessarily translate into effects in humans. Further research in humans is needed.
Lecithin is not a single substance. It’s a group of chemicals, includingphospholipids(fat plus phosphate).The fats are primarily linoleic acid n-6 (LA),polyunsaturated fatty acids (PUFAs), and monounsaturated fatty acids (MUFAs).
Two level tablespoons (15 g) of soya lecithin granules contained approximately the following nutrients:
Other lecithin products, like soybean lecithin oil, have a different nutrition profile. One tablespoon (13.6 g) of soybean lecithin oil contains the following:
Growing conditions can affect the amounts of a plant-derived product’s fatty acids and phospholipids.
Food Sources
Lecithin is found in foods that include:
Lecithin is used in cooking as an emulsifier; it helps stabilize ingredients that aren’t easily mixed, like oil and water. It’s also used in CBD edibles, typically as soy lecithin.
In most cases, lecithin supplements are safe for you to use. Side effects and possibly an allergic reaction can occur, though, so ask your healthcare provider before taking lecithin or any other supplement. This is especially important if you:
Side effects from lecithin have included the following:
Seek immediate medical attention if you believe you have a side effect from lecithin.
Is Lecithin Safe For You?Lecithin is generally considered safe at suggested doses. However, it is possible to experience side effects. Consult your healthcare provider before taking this or any supplement.
Is Lecithin Safe For You?
Lecithin is generally considered safe at suggested doses. However, it is possible to experience side effects. Consult your healthcare provider before taking this or any supplement.
Precautions
Keep the following precautions in mind when using lecithin:
Interactions
The following interactions may occur with lecithin:
It is essential to carefully read a supplement’s ingredients list and nutrition facts panel to know which ingredients are in the product and how much of each ingredient is included. Please review this supplement label with your healthcare provider to discuss potential interactions with foods, other supplements, and medications.
Dosage: How Much Lecithin Should I Take?
There is no specific dosage of lecithin that’s recommended and it may vary depending on the intended purpose. In studies, the following dosages were used for the following conditions:
Generally, never take more than the dose suggested on the label. Consult with your healthcare provider or pharmacist if you have any questions.
For choline, often in lecithin form, the tolerable upper limits for dosage are 3,500 mg in all adults, including pregnant people. Excessive amounts can cause sweating, vomiting, low blood pressure, and liver damage.
Supplements similar in action to lecithin include the following:
Lecithin is available as a capsule or pill, and also is sold as granules or powders.
Summary
Lecithin contains phospholipids. It may be found in specific foods or taken as a supplement. It is said to aid in the function of the brain, nerves, and other organs.
Lecithin has been studied for its use in preventing or treating various health conditions. However, the evidence supporting its use for these conditions is weak; more studies are needed.
Lecithin is thought to be safe. Still, check with your healthcare provider before taking any supplements. You may need to avoid it if you have chronic kidney disease due to potential phosphorous content.
23 Sources
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Bostock EL, Morse CI, Winwood K, et al.Omega-3 fatty acids and vitamin D in immobilisation: Part A- Modulation of appendicular mass content, composition and structure.J Nutr Health Aging. 2017;21(1):51-58. doi:10.1007/s12603-016-0710-5
Robert C, Couëdelo L, Vaysse C, et al.Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention.Biochimie. 2020;169:121-132. doi:10.1016/j.biochi.2019.11.017
Dai Y, Tang H, Pang S.The crucial roles of phospholipids in aging and lifespan regulation.Front Physiol. 2021;12:775648. doi:10.3389/fphys.2021.775648
University of Rochester Medical Center.Lecithin.
Javaid S, Farooq T, Rehman Z, et al.Dynamics of choline-containing phospholipids in traumatic brain injury and associated comorbidities.Int J Mol Sci. 2021;22(21):11313. doi:10.3390/ijms222111313
Drugs and Lactation Database (LactMed).Lecithin.
Mitchell KB, Johnson HM, Rodríguez JM, et al.Academy of Breastfeeding Medicine clinical protocol# 36: the mastitis spectrum, revised 2022.Breastfeed Med. 2022;17(5):360-76. doi:10.1089/bfm.2022.29207.kbm
Hirose A, Terauchi M, Osaka Y, et al.Effect of soy lecithin on fatigue and menopausal symptoms in middle-aged women: a randomized, double-blind, placebo-controlled study.Nutr J. 2018;17(1):4. doi:10.1186/s12937-018-0314-5
Tammenmaa-Aho I, Asher R, Soares-Weiser K, Bergman H.Cholinergic medication for antipsychotic-induced tardive dyskinesia.Cochrane Database Syst Rev. 2018;3(3):CD000207. doi:10.1002/14651858.CD000207.pub2
Stremmel W, Vural H, Evliyaoglu O, et al.Efficacy of enteric lecithin (phosphatidylcholine) in the treatment of ulcerative colitis: a meta-analysis.MMW Fortschritte der Medizin. 2022;164(Suppl 7):3-11. doi:10.1007/s15006-022-0832-0
Miclotte L, De Paepe E, Li Q, et al.Long term exposure of human gut microbiota with high and low emulsifier sensitivity to soy lecithin in M-SHIME model.bioRxiv. 2021:2021-12. doi:10.1101/2021.12.16.472798
Stremmel W, Vural H, Evliyaoglu O, Weiskirchen R.Delayed-release phosphatidylcholine is effective for treatment of ulcerative colitis: A meta-analysis.Dig Dis. 2021;39(5):508-515. doi:10.1159/000514355
Stremmel W, Vural H, Evliyaoglu O, et al.Delayed-release phosphatidylcholine is effective for treatment of ulcerative colitis: A meta-analysis.Dig Dis. 2021;39(5):508-515. doi:10.1159/000514355
Lois A, Droullard D, Lee J, Flum D.Patient decision-making in symptomatic gallbladder disease.Surg Endosc. 2022 Aug;36(8):6271-6277. doi:10.1007/s00464-022-09115-y
Maev IV, Samsonov AA, Palgova LK, et al.Effectiveness of phosphatidylcholine as adjunctive therapy in improving liver function tests in patients with non-alcoholic fatty liver disease and metabolic comorbidities: Real-life observational study from Russia.BMJ Open Gastroenterol. 2020;7(1):e000368. doi:10.1136/bmjgast-2019-000368
Nasab ME, Takzaree N, Saffari PM, Partoazar A.In vitroantioxidant activity andin vivowound-healing effect of lecithin liposomes: a comparative study.J Comp Eff Res. 2019;8(8):633-643. doi:10.2217/cer-2018-0128
USDA.FoodData Central.
NIH Office of Dietary Supplements.Vitamin K.
NIH Office of Dietary Supplements.Choline.
Tuominen M, Karp HJ, Itkonen ST.Phosphorus-containing food additives in the food supply-An audit of products on supermarket shelves.J Ren Nutr. 2022;32(1):30-38. doi:10.1053/j.jrn.2021.07.010
Lordan R, Tsoupras A, Zabetakis I.Phospholipids of animal and marine origin: Structure, function, and anti-inflammatory properties.Molecules. 2017; 22(11):1964. https://doi.org/10.3390/molecules22111964
Robert C, Couëdelo L, Vaysse C, Michalski MC.Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention.Biochimie. 2020 Feb;169:121-132. doi:10.1016/j.biochi.2019.11.017
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